6 332

Cited 0 times in

Red blood cell distribution width is an independent predictor of mortality in patients with gram-negative bacteremia

DC FieldValueLanguage
dc.contributor.author김혜원-
dc.contributor.author한상훈-
dc.contributor.author송영구-
dc.contributor.author구남수-
dc.contributor.author송제은-
dc.contributor.author김민형-
dc.contributor.author안진영-
dc.contributor.author김선빈-
dc.contributor.author오동현-
dc.contributor.author김용찬-
dc.contributor.author오형중-
dc.contributor.author김준명-
dc.contributor.author정수진-
dc.contributor.author김창오-
dc.contributor.author최준용-
dc.date.accessioned2014-12-19T17:40:15Z-
dc.date.available2014-12-19T17:40:15Z-
dc.date.issued2012-
dc.identifier.issn1073-2322-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91849-
dc.description.abstractRed blood cell distribution width (RDW) is known to be a predictor of severe morbidity and mortality in some chronic diseases such as congestive heart failure. However, to our knowledge, little is known about RDW as a predictor of mortality in patients with Gram-negative bacteremia, a major nosocomial cause of intra-abdominal infections, urinary tract infections, and primary bacteremia. Therefore, we investigated whether RDW is an independent predictor of mortality in patients with Gram-negative bacteremia. Clinical characteristics, laboratory parameters, and outcomes of 161 patients with Gram-negative bacteremia from November 2010 to March 2011 diagnosed at Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, were retrospectively analyzed. The main outcome measure was 28-day all-cause mortality. The 28-day mortality rate was significantly higher in the increased RDW group compared with the normal RDW group (P < 0.001). According to multivariate Cox proportional hazard analysis, RDW levels at the onset of bacteremia (per 1% increase, P = 0.036), the Charlson index (per 1-point increase, P < 0.001), and the Sequential Organ Failure Assessment score (per 1-point increase, P = 0.001) were independent risk factors for 28-day mortality. Moreover, the nonsurvivor group had significantly higher RDW levels 72 h after the onset of bacteremia than did the survivor group (P = 0.001). In addition, the area under the curve of RDW at the onset of bacteremia, the 72-h RDW, and the Sequential Organ Failure Assessment score for 28-day mortality were 0.764 (P = 0.001), 0.802 (P < 0.001), and 0.703 (P = 0.008), respectively. Red blood cell distribution width at the onset of bacteremia was an independent predictor of mortality in patients with Gram-negative bacteremia. Also, 72-h RDW could be a predictor for all-cause mortality in patients with Gram-negative bacteremia.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfSHOCK-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBacteremia/blood-
dc.subject.MESHBacteremia/mortality*-
dc.subject.MESHCause of Death-
dc.subject.MESHErythrocytes, Abnormal/microbiology-
dc.subject.MESHErythrocytes, Abnormal/pathology*-
dc.subject.MESHFemale-
dc.subject.MESHGram-Negative Bacterial Infections/blood-
dc.subject.MESHGram-Negative Bacterial Infections/mortality*-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHROC Curve-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.titleRed blood cell distribution width is an independent predictor of mortality in patients with gram-negative bacteremia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorKu, Nam Su-
dc.contributor.googleauthorKim, Hye-won-
dc.contributor.googleauthorOh, Hyung Jung-
dc.contributor.googleauthorKim, Yong Chan-
dc.contributor.googleauthorKim, Min Hyung-
dc.contributor.googleauthorSong, Je Eun-
dc.contributor.googleauthorOh, Dong Hyun-
dc.contributor.googleauthorAhn, Jin Young-
dc.contributor.googleauthorKim, Sun Bean-
dc.contributor.googleauthorJeong, Su Jin-
dc.contributor.googleauthorHan, Sang Hoon-
dc.contributor.googleauthorKim, Chang Oh-
dc.contributor.googleauthorSong, Young Goo-
dc.contributor.googleauthorKim, June Myung-
dc.contributor.googleauthorChoi, Jun Yong-
dc.identifier.doi22683729-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01176-
dc.contributor.localIdA04286-
dc.contributor.localIdA02037-
dc.contributor.localIdA00189-
dc.contributor.localIdA02059-
dc.contributor.localIdA00480-
dc.contributor.localIdA02267-
dc.contributor.localIdA00547-
dc.contributor.localIdA02361-
dc.contributor.localIdA00752-
dc.contributor.localIdA02417-
dc.contributor.localIdA00953-
dc.contributor.localIdA03638-
dc.contributor.localIdA01044-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ02658-
dc.identifier.eissn1540-0514-
dc.identifier.pmid22683729-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00024382-201208000-00002&LSLINK=80&D=ovft-
dc.subject.keywordRDW-
dc.subject.keywordpredictor-
dc.subject.keywordmortality-
dc.subject.keywordGram-negative bacteremia-
dc.contributor.alternativeNameKim, Hye Won-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameKim, Min Hyung-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameKim, Sun Bean-
dc.contributor.alternativeNameOh, Dong Hyun-
dc.contributor.alternativeNameKim, Yong Chan-
dc.contributor.alternativeNameOh, Hyung Jung-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.affiliatedAuthorKim, Hye Won-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.contributor.affiliatedAuthorSong, Je Eun-
dc.contributor.affiliatedAuthorKim, Min Hyung-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorKim, Sun Bean-
dc.contributor.affiliatedAuthorOh, Dong Hyun-
dc.contributor.affiliatedAuthorKim, Yong Chan-
dc.contributor.affiliatedAuthorOh, Hyung Jung-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.citation.volume38-
dc.citation.number2-
dc.citation.startPage123-
dc.citation.endPage127-
dc.identifier.bibliographicCitationSHOCK, Vol.38(2) : 123-127, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.