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Application of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis in Korean patients with undifferentiated arthritis

Authors
 SJ Jung  ;  Y Kang  ;  YJ Ha  ;  KH Lee  ;  SW Lee  ;  S-K Lee  ;  Y-B Park 
Citation
 Scandinavian Journal of Rheumatology, Vol.41(3) : 192-195, 2012 
Journal Title
 Scandinavian Journal of Rheumatology 
ISSN
 0300-9742 
Issue Date
2012
MeSH
Adult ; Arthritis, Rheumatoid/blood ; Arthritis, Rheumatoid/classification* ; Arthritis, Rheumatoid/diagnosis ; C-Reactive Protein/analysis ; Cohort Studies ; Diagnostic Errors ; Enzyme-Linked Immunosorbent Assay ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Nephelometry and Turbidimetry ; Peptides, Cyclic/antagonists & inhibitors ; Peptides, Cyclic/blood* ; Republic of Korea ; Rheumatoid Factor/blood* ; Severity of Illness Index
Keywords
Adult ; Arthritis, Rheumatoid/blood ; Arthritis, Rheumatoid/classification* ; Arthritis, Rheumatoid/diagnosis ; C-Reactive Protein/analysis ; Cohort Studies ; Diagnostic Errors ; Enzyme-Linked Immunosorbent Assay ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Nephelometry and Turbidimetry ; Peptides, Cyclic/antagonists & inhibitors ; Peptides, Cyclic/blood* ; Republic of Korea ; Rheumatoid Factor/blood* ; Severity of Illness Index
Abstract
OBJECTIVE: The aim of this study was to determine how many patients with undifferentiated arthritis (UA) are classified as patients with rheumatoid arthritis (RA) by the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria for RA. METHODS: The 2010 ACR/EULAR criteria for RA were applied to 102 patients with UA. UA is defined as an inflammatory arthritis that does not meet any criteria for a definitive diagnosis. We analysed discrepancy in the classification between previous criteria and the 2010 criteria by identifying patients who were categorized as those with RA. RESULTS: The mean age of the patients was 46.8 ± 14.3 years. Rheumatoid factor (RF) was positive in 36 patients (35.2%), and 30 patients (29.5%) were positive for anti-cyclic citrullinated peptide antibody (anti-CCP). The 2010 ACR/EULAR criteria classified 33 patients (32.4%) as having RA, and 31 of them (93.9%) had the involvement of 1-3 small joints. All patients were seropositive, and 25 of them (75.8%) had high positive RF or anti-CCP. Seropositivity and small joint involvement was significantly different between patients who were classified with RA and those who were not (p < 0.001). CONCLUSION: Using the 2010 ACR/EULAR criteria, 32.4% of patients with UA were classified as having RA, and all were seropositive. Most of the UA patients with high positive RF or anti-CCP could be classified as having RA when we applied the 2010 ACR/EULAR criteria.
Full Text
http://informahealthcare.com/doi/abs/10.3109/03009742.2012.654816
DOI
22401568
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Yoon(강윤)
Park, Yong Beom(박용범)
Lee, Kwang Hoon(이광훈)
Lee, Sang Won(이상원) ORCID logo https://orcid.org/0000-0002-8038-3341
Lee, Soo Kon(이수곤)
Jung, Se Jin(정세진)
Ha, You Jung(하유정)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/91833
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