Cited 36 times in
Poor prediction of potentially drug-resistant pathogens using current criteria of health care-associated pneumonia
DC Field | Value | Language |
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dc.contributor.author | 박무석 | - |
dc.contributor.author | 박병훈 | - |
dc.contributor.author | 박선철 | - |
dc.contributor.author | 장준 | - |
dc.contributor.author | 정지예 | - |
dc.contributor.author | 강영애 | - |
dc.contributor.author | 김세규 | - |
dc.contributor.author | 김영삼 | - |
dc.contributor.author | 김은영 | - |
dc.date.accessioned | 2014-12-19T17:38:27Z | - |
dc.date.available | 2014-12-19T17:38:27Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91791 | - |
dc.description.abstract | BACKGROUND: Health care-associated pneumonia (HCAP) includes a broad range of patients having frequent or chronic contact with health care systems. However, the relationship between current defining criteria for HCAP and the risk of potentially drug-resistant (PDR) pathogens is controversial. METHODS: We retrospectively evaluated patients admitted to Severance Hospital in South Korea with culture-positive pneumonia from January 2008 to December 2009. We analyzed the associations between risk factors for HCAP and infection with PDR pathogens, and developed a new scoring system to predict infection with PDR pathogens. RESULTS: Among 339 patients, PDR pathogens were observed in 122 (36.0%). PDR pathogens were more common in HCAP than community-acquired pneumonia (CAP) (48.5% versus 23.8%, P<0.001). In a logistic regression, prior hospitalization within 90 days of pneumonia (OR=2.51, P=0.003), recent treatment with antimicrobials (OR=2.35, P=0.039), and nasogastric tube feeding (OR=15.28, P<0.001) were independently associated with PDR pathogens. For the prediction of PDR pathogens, the sensitivity and specificity of current HCAP criteria were 66.4% and 60.4%, respectively, and 68.0% and 67.3%, respectively, for the new scoring system. Moreover, the new scoring system showed better diagnostic accuracy than current HCAP criteria (area under curve=0.711 versus 0.634, P<0.001). CONCLUSIONS: The current HCAP criteria are poor predictors of PDR pathogens and all patients with HCAP should not be empirically treated for these pathogens. To avoid excessive antibiotic use, individual risk stratification approaches should be considered. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | RESPIRATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Bacterial Agents/therapeutic use | - |
dc.subject.MESH | Cross Infection/diagnosis* | - |
dc.subject.MESH | Cross Infection/drug therapy | - |
dc.subject.MESH | Cross Infection/microbiology | - |
dc.subject.MESH | Drug Resistance, Multiple, Bacterial* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/diagnosis* | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/drug therapy | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/microbiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pneumonia, Bacterial/diagnosis* | - |
dc.subject.MESH | Pneumonia, Bacterial/microbiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Young Adult | - |
dc.title | Poor prediction of potentially drug-resistant pathogens using current criteria of health care-associated pneumonia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Seon Cheol Park | - |
dc.contributor.googleauthor | Young Ae Kang | - |
dc.contributor.googleauthor | Byung Hoon Park | - |
dc.contributor.googleauthor | Eun Young Kim | - |
dc.contributor.googleauthor | Moo Suk Park | - |
dc.contributor.googleauthor | Young Sam Kim | - |
dc.contributor.googleauthor | Se Kyu Kim | - |
dc.contributor.googleauthor | Joon Chang | - |
dc.contributor.googleauthor | Ji Ye Jung | - |
dc.identifier.doi | 10.1016/j.rmed.2012.04.003 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01457 | - |
dc.contributor.localId | A01478 | - |
dc.contributor.localId | A01505 | - |
dc.contributor.localId | A03472 | - |
dc.contributor.localId | A03735 | - |
dc.contributor.localId | A00057 | - |
dc.contributor.localId | A00602 | - |
dc.contributor.localId | A00707 | - |
dc.contributor.localId | A00811 | - |
dc.relation.journalcode | J02615 | - |
dc.identifier.eissn | 1532-3064 | - |
dc.identifier.pmid | 22560114 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0954611112001552 | - |
dc.subject.keyword | Pneumonia | - |
dc.subject.keyword | Health care-associated | - |
dc.subject.keyword | Drug-resistant | - |
dc.contributor.alternativeName | Park, Moo Suk | - |
dc.contributor.alternativeName | Park, Byung Hoon | - |
dc.contributor.alternativeName | Park, Seon Cheol | - |
dc.contributor.alternativeName | Chang, Joon | - |
dc.contributor.alternativeName | Jung, Ji Ye | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.alternativeName | Kim, Se Kyu | - |
dc.contributor.alternativeName | Kim, Young Sam | - |
dc.contributor.alternativeName | Kim, Eun Young | - |
dc.contributor.affiliatedAuthor | Park, Moo Suk | - |
dc.contributor.affiliatedAuthor | Park, Byung Hoon | - |
dc.contributor.affiliatedAuthor | Park, Seon Cheol | - |
dc.contributor.affiliatedAuthor | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Jung, Ji Ye | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kim, Se Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Young Sam | - |
dc.contributor.affiliatedAuthor | Kim, Eun Young | - |
dc.citation.volume | 106 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1311 | - |
dc.citation.endPage | 1319 | - |
dc.identifier.bibliographicCitation | RESPIRATORY MEDICINE, Vol.106(9) : 1311-1319, 2012 | - |
dc.identifier.rimsid | 31193 | - |
dc.type.rims | ART | - |
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