Cited 20 times in
Significant reduction of atrial defibrillation threshold and inducibility by catheter ablation of atrial fibrillation
DC Field | Value | Language |
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dc.contributor.author | 박준범 | - |
dc.contributor.author | 박희남 | - |
dc.contributor.author | 심재민 | - |
dc.contributor.author | 엄재선 | - |
dc.contributor.author | 이문형 | - |
dc.contributor.author | 정보영 | - |
dc.contributor.author | 황의석 | - |
dc.date.accessioned | 2014-12-19T17:33:18Z | - |
dc.date.available | 2014-12-19T17:33:18Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0147-8389 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91627 | - |
dc.description.abstract | Background: Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) has antiarrhythmic effects by multiple mechanisms. We hypothesized that RFCA curtails atrial defibrillation threshold (A-DFT) and postablation induction pacing cycle length (iPCL), making critical mass reduction one potential mechanism by which antiarrhythmic effect is achieved. Methods: We included 289 patients with AF (male 77.9%, 55.7 ± 10.8 years old; 197 paroxysmal AF: 92 persistent AF) who underwent RFCA. A-DFT (serial internal cardioversion 2, 3, 5, 7, and 10 J) and iPCL (serial 10 mA 10-second atrial pacing with pacing cycle length 250, 200, 190, 180, 170, 160, and 150 ms) were evaluated before and after RFCA. Results: (1) RFCA of AF reduced the A-DFT from 6.7 ± 3.7 J to 3.0 ± 3.0 J (P < 0.001). (2) AF ablation reduced AF inducibility from 95.4% before the procedure to 56.3% after the procedure (P < 0.001), and the iPCL from 194.8 ± 32.6 to 160.9 ± 26.2 ms (P < 0.001). (3) In patients who underwent a greater number of ablation lines, the post-RFCA A-DFT (P < 0.001) was lower, and %ΔA-DFT (P = 0.003) and proportion of atrial tachycardia (P = 0.022) were higher than those with a lower number of ablation lines. Conclusion: AF ablation significantly reduced A-DFT, AF inducibility, and iPCL, and the degree of their reduction was related to the number of ablation lines. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Atrial Fibrillation/physiopathology | - |
dc.subject.MESH | Atrial Fibrillation/surgery* | - |
dc.subject.MESH | Cardiac Pacing, Artificial* | - |
dc.subject.MESH | Catheter Ablation/methods* | - |
dc.subject.MESH | Chi-Square Distribution | - |
dc.subject.MESH | Electrophysiologic Techniques, Cardiac | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Significant reduction of atrial defibrillation threshold and inducibility by catheter ablation of atrial fibrillation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | EUI-SEOCK HWANG | - |
dc.contributor.googleauthor | GI BYUNG NAM | - |
dc.contributor.googleauthor | BOYOUNG JOUNG | - |
dc.contributor.googleauthor | JUNBEOM PARK | - |
dc.contributor.googleauthor | JIHEI SARA LEE | - |
dc.contributor.googleauthor | JAEMIN SHIM | - |
dc.contributor.googleauthor | JAE-SUN UHM | - |
dc.contributor.googleauthor | MOON HYOUNG LEE | - |
dc.contributor.googleauthor | HUI-NAM PAK | - |
dc.identifier.doi | 10.1111/j.1540-8159.2012.03517.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01670 | - |
dc.contributor.localId | A01776 | - |
dc.contributor.localId | A02206 | - |
dc.contributor.localId | A02337 | - |
dc.contributor.localId | A02766 | - |
dc.contributor.localId | A03609 | - |
dc.contributor.localId | A04480 | - |
dc.relation.journalcode | J02457 | - |
dc.identifier.eissn | 1540-8159 | - |
dc.identifier.pmid | 22978799 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1540-8159.2012.03517.x/abstract | - |
dc.subject.keyword | Adolescent | - |
dc.subject.keyword | Adult | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Aged, 80 and over | - |
dc.subject.keyword | Analysis of Variance | - |
dc.subject.keyword | Atrial Fibrillation/physiopathology | - |
dc.subject.keyword | Atrial Fibrillation/surgery* | - |
dc.subject.keyword | Cardiac Pacing, Artificial* | - |
dc.subject.keyword | Catheter Ablation/methods* | - |
dc.subject.keyword | Chi-Square Distribution | - |
dc.subject.keyword | Electrophysiologic Techniques, Cardiac | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Treatment Outcome | - |
dc.contributor.alternativeName | Park, Jun Beom | - |
dc.contributor.alternativeName | Pak, Hui Nam | - |
dc.contributor.alternativeName | Shim, Jae Min | - |
dc.contributor.alternativeName | Uhm, Jae Sun | - |
dc.contributor.alternativeName | Lee, Moon Hyoung | - |
dc.contributor.alternativeName | Joung, Bo Young | - |
dc.contributor.alternativeName | Hwang, Eui Seock | - |
dc.contributor.affiliatedAuthor | Park, Jun Beom | - |
dc.contributor.affiliatedAuthor | Pak, Hui Nam | - |
dc.contributor.affiliatedAuthor | Shim, Jae Min | - |
dc.contributor.affiliatedAuthor | Uhm, Jae Sun | - |
dc.contributor.affiliatedAuthor | Lee, Moon Hyoung | - |
dc.contributor.affiliatedAuthor | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Hwang, Eui Seock | - |
dc.citation.volume | 35 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1428 | - |
dc.citation.endPage | 1435 | - |
dc.identifier.bibliographicCitation | PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, Vol.35(12) : 1428-1435, 2012 | - |
dc.identifier.rimsid | 29521 | - |
dc.type.rims | ART | - |
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