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Visceral fat thickness is associated with carotid atherosclerosis in peritoneal dialysis patients
DC Field | Value | Language |
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dc.contributor.author | 오형중 | - |
dc.contributor.author | 유동은 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 이미정 | - |
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 최규헌 | - |
dc.contributor.author | 김승준 | - |
dc.contributor.author | 한승혁 | - |
dc.contributor.author | 박정탁 | - |
dc.date.accessioned | 2014-12-19T17:31:47Z | - |
dc.date.available | 2014-12-19T17:31:47Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1930-7381 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91580 | - |
dc.description.abstract | Visceral fat has been known to associate with atherosclerosis, inflammation, and insulin resistance. However, the influence of visceral fat on cardiovascular disease (CVD) in peritoneal dialysis (PD) patients has never been elucidated. We investigated whether visceral fat thickness (VFT) has a predictive role in carotid atherosclerosis determined by carotid intima-media thickness (cIMT) in PD patients. A cross-sectional study was undertaken in 88 prevalent PD patients. BMI and waist circumference (WC) were measured as anthropometric indexes of obesity. VFT and subcutaneous fat thickness (SFT) were determined by sonographic measurement of abdominal fat. Carotid atherosclerosis was defined as increased cIMT (>1.0 mm) or presence of plaque. Thirty-two (36.3%) patients had carotid atherosclerosis. Patients with carotid atherosclerosis showed significantly higher VFT, BMI, and WC. In univariate logistic analysis, BMI, WC, and VFT except SFT were significant risk factors of carotid atherosclerosis. However, multivariate analysis revealed VFT was an independent factor associated with carotid atherosclerosis after adjusting for demographic, biochemical parameters, and anthropometric indexes (per 1 mm increase, odds ratio (OR) = 2.294, 95% confidence interval: 1.048-5.021, P = 0.038). When the patients were divided into three groups according to VFT, log high sensitivity C-reactive protein (hs-CRP), and homeostasis model assessment-insulin resistance (HOMA(IR)) were both higher in the third tertile compared to other tertiles. In conclusion, VFT, not SFT, is independently associated with carotid atherosclerosis in PD patients. Therefore sonographic measurement of VFT could be useful to stratify the risk of cardiovascular disease in PD patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | OBESITY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Carotid Artery Diseases/diagnostic imaging | - |
dc.subject.MESH | Carotid Artery Diseases/etiology* | - |
dc.subject.MESH | Carotid Artery Diseases/physiopathology | - |
dc.subject.MESH | Carotid Intima-Media Thickness | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intra-Abdominal Fat/diagnostic imaging | - |
dc.subject.MESH | Intra-Abdominal Fat/pathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Peritoneal Dialysis* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Surveys and Questionnaires | - |
dc.subject.MESH | Waist Circumference* | - |
dc.title | Visceral fat thickness is associated with carotid atherosclerosis in peritoneal dialysis patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Mi Jung Lee | - |
dc.contributor.googleauthor | Dong Ho Shin | - |
dc.contributor.googleauthor | Seung Jun Kim | - |
dc.contributor.googleauthor | Hyung Jung Oh | - |
dc.contributor.googleauthor | Dong Eun Yoo | - |
dc.contributor.googleauthor | Jwa-Kyung Kim | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Kyu Hun Choi | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.identifier.doi | 21818151 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02417 | - |
dc.contributor.localId | A02461 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A04043 | - |
dc.contributor.localId | A04304 | - |
dc.contributor.localId | A00931 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02097 | - |
dc.contributor.localId | A00659 | - |
dc.contributor.localId | A02773 | - |
dc.relation.journalcode | J02404 | - |
dc.identifier.eissn | 1930-739X | - |
dc.identifier.pmid | 21818151 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1038/oby.2011.245/abstract | - |
dc.subject.keyword | Body Mass Index | - |
dc.subject.keyword | C-Reactive Protein/metabolism | - |
dc.subject.keyword | Carotid Artery Diseases/diagnostic imaging | - |
dc.subject.keyword | Carotid Artery Diseases/etiology* | - |
dc.subject.keyword | Carotid Artery Diseases/physiopathology | - |
dc.subject.keyword | Carotid Intima-Media Thickness | - |
dc.subject.keyword | Cross-Sectional Studies | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Intra-Abdominal Fat/diagnostic imaging | - |
dc.subject.keyword | Intra-Abdominal Fat/pathology* | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Peritoneal Dialysis* | - |
dc.subject.keyword | Risk Factors | - |
dc.subject.keyword | Surveys and Questionnaires | - |
dc.subject.keyword | Waist Circumference* | - |
dc.contributor.alternativeName | Oh, Hyung Jung | - |
dc.contributor.alternativeName | Yoo, Dong Eun | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.alternativeName | Lee, Mi Jung | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.alternativeName | Choi, Kyu Hun | - |
dc.contributor.alternativeName | Kim, Seung Jun | - |
dc.contributor.alternativeName | Han, Seung Hyeok | - |
dc.contributor.alternativeName | Park, Jung Tak | - |
dc.contributor.alternativeName | Shin, Dong Ho | - |
dc.contributor.affiliatedAuthor | Oh, Hyung Jung | - |
dc.contributor.affiliatedAuthor | Yoo, Dong Eun | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Choi, Kyu Hun | - |
dc.contributor.affiliatedAuthor | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | Park, Jung Tak | - |
dc.contributor.affiliatedAuthor | Shin, Dong Ho | - |
dc.contributor.affiliatedAuthor | Kim, Seung Jun | - |
dc.contributor.affiliatedAuthor | Lee, Mi Jung | - |
dc.citation.volume | 20 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1301 | - |
dc.citation.endPage | 1307 | - |
dc.identifier.bibliographicCitation | OBESITY, Vol.20(6) : 1301-1307, 2012 | - |
dc.identifier.rimsid | 29318 | - |
dc.type.rims | ART | - |
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