2 231

Cited 75 times in

Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy

DC FieldValueLanguage
dc.contributor.author김좌경-
dc.contributor.author유태현-
dc.contributor.author최규헌-
dc.contributor.author한승혁-
dc.contributor.author박정탁-
dc.contributor.author강신욱-
dc.contributor.author오형중-
dc.contributor.author김승준-
dc.contributor.author유동은-
dc.date.accessioned2014-12-19T17:29:45Z-
dc.date.available2014-12-19T17:29:45Z-
dc.date.issued2012-
dc.identifier.issn0931-0509-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91515-
dc.description.abstractBACKGROUND: A potential independent association was recently demonstrated between high red blood cell distribution width (RDW) and the risk of all-cause mortality in patients with cardiovascular disease, although the mechanism remains unclear. However, there have been no reports on the relationship between RDW and mortality in acute kidney injury (AKI) patients treated with continuous renal replacement therapy (CRRT). In this study, we assessed whether RDW was associated with mortality in AKI patients on CRRT treatment in the intensive care unit (ICU). METHODS: We enrolled 470 patients with AKI who were treated with CRRT at the Yonsei University Medical Center ICU from August 2007 to September 2009 in this study. We performed a retrospective analysis of demographic, biochemical parameters and patient outcomes. Following CRRT treatment, 28-day all-cause mortality was evaluated. RESULTS: At the initiation of CRRT treatment, RDW level was significantly correlated with white blood cell count, hemoglobin (Hb) and total cholesterol. Patients with high RDW levels exhibited significantly higher 28-day mortality rates than patients with low RDW levels (P < 0.01). Baseline RDW level, Sequential Organ Failure Assessment (SOFA) score, low mean arterial pressure (MAP) and low cholesterol levels were independent risk factors for mortality. In multivariate Cox proportional hazard analyses, RDW at CRRT initiation was an independent predictor for 28-day all-cause mortality after adjusting for age, gender, MAP, Hb, albumin, total cholesterol, C-reactive protein and SOFA score. CONCLUSION: Our study demonstrates that RDW could be an additive predictor for all-cause mortality in AKI patients on CRRT treatment in the ICU.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfNephrology Dialysis Transplantation-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRed blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHyung Jung Oh-
dc.contributor.googleauthorJung Tak Park-
dc.contributor.googleauthorJwa-Kyung Kim-
dc.contributor.googleauthorDong Eun Yoo-
dc.contributor.googleauthorSeung Jun Kim-
dc.contributor.googleauthorSeung Hyeok Han-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorKyu Hun Choi-
dc.contributor.googleauthorTae-Hyun Yoo-
dc.identifier.doi10.1093/ndt/gfr307-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00931-
dc.contributor.localIdA02526-
dc.contributor.localIdA04043-
dc.contributor.localIdA04304-
dc.contributor.localIdA01654-
dc.contributor.localIdA00053-
dc.contributor.localIdA02417-
dc.contributor.localIdA02461-
dc.contributor.localIdA00659-
dc.relation.journalcodeJ02316-
dc.identifier.urlhttp://ndt.oxfordjournals.org/content/27/2/589.long-
dc.contributor.alternativeNameKim, Jwa Kyung-
dc.contributor.alternativeNameYoo, Tae Hyun-
dc.contributor.alternativeNameChoi, Kyu Hun-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.alternativeNamePark, Jung Tak-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameOh, Hyung Jung-
dc.contributor.alternativeNameKim, Seung Jun-
dc.contributor.alternativeNameYoo, Dong Eun-
dc.contributor.affiliatedAuthorKim, Jwa Kyung-
dc.contributor.affiliatedAuthorYoo, Tae Hyun-
dc.contributor.affiliatedAuthorChoi, Kyu Hun-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.contributor.affiliatedAuthorPark, Jung Tak-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorOh, Hyung Jung-
dc.contributor.affiliatedAuthorYoo, Dong Eun-
dc.contributor.affiliatedAuthorKim, Seung Jun-
dc.citation.volume27-
dc.citation.number2-
dc.citation.startPage589-
dc.citation.endPage594-
dc.identifier.bibliographicCitationNephrology Dialysis Transplantation, Vol.27(2) : 589-594, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.