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Rosai-Dorfman Disease in the breast with increased IgG4 expressing plasma cells: a case report
DC Field | Value | Language |
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dc.contributor.author | 구자승 | - |
dc.contributor.author | 박세호 | - |
dc.contributor.author | 양우익 | - |
dc.date.accessioned | 2014-12-19T17:23:20Z | - |
dc.date.available | 2014-12-19T17:23:20Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1738-1843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91315 | - |
dc.description.abstract | Rosai-Dorfman disease (RDD) can present in any anatomic site, but breast involvement is rarely reported. Recently, a relationship between RDD and IgG4-related sclerosing disease has been suggested. Here we report another case of RDD with overlapping features of IgG4-related sclerosing disease occurring in a right breast of a 62-year-old female. On microscopic examination, the mass demonstrated a characteristic zonal pattern of proliferation of large polygonal histiocytes and lymphoplasma cells with stromal fibrosis. Emperipolesis was observed in histiocytes with abundant cytoplasm, which showed immunoreactivity for S-100 protein and CD68; the diagnosis of RDD was made. Sheets of plasma cells in the fibrotic stroma demonstrated positive reactions for IgG and IgG4. The mean count of IgG4-positive plasma cells was 100.2/high power field, and the ratio of IgG4/IgG was 56.7%. Additional findings of stromal fibrosis and obliteration of preexisting breast lobules suggested overlapping features with IgG4-related sclerosing disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | KOREAN JOURNAL OF PATHOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Rosai-Dorfman Disease in the breast with increased IgG4 expressing plasma cells: a case report | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Yoon Jin Cha | - |
dc.contributor.googleauthor | Woo Ick Yang | - |
dc.contributor.googleauthor | Se Ho Park | - |
dc.contributor.googleauthor | Ja Seung Koo | - |
dc.identifier.doi | 23136577 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00198 | - |
dc.contributor.localId | A01524 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A04001 | - |
dc.relation.journalcode | J02092 | - |
dc.identifier.eissn | 2092-8920 | - |
dc.identifier.pmid | 23136577 | - |
dc.subject.keyword | Breast | - |
dc.subject.keyword | Histiocytosis | - |
dc.subject.keyword | Histiocytosis, sinus | - |
dc.subject.keyword | Immunoglobulin G | - |
dc.contributor.alternativeName | Koo, Ja Seung | - |
dc.contributor.alternativeName | Park, Se Ho | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Koo, Ja Seung | - |
dc.contributor.affiliatedAuthor | Park, Se Ho | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | 구자승 | - |
dc.citation.volume | 46 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 489 | - |
dc.citation.endPage | 493 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF PATHOLOGY , Vol.46(5) : 489-493, 2012 | - |
dc.identifier.rimsid | 30101 | - |
dc.type.rims | ART | - |
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