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Hypodipsic hypernatremia leading to reversible renal failure following surgery for craniopharyngioma
DC Field | Value | Language |
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dc.contributor.author | 권아름 | - |
dc.contributor.author | 김호성 | - |
dc.contributor.author | 신재일 | - |
dc.contributor.author | 채현욱 | - |
dc.date.accessioned | 2014-12-19T17:14:11Z | - |
dc.date.available | 2014-12-19T17:14:11Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0334-018X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91033 | - |
dc.description.abstract | Thirst is stimulated by increases in effective plasma osmolality that are detected by cerebral osmoreceptors located in the vascular organ of the lamina terminalis. However, surgical destruction or organic lesions of the lamina terminalis decrease the sensation of thirst in response to increased plasma osmolality. A 17-year-old boy who was diagnosed with craniopharyngioma at the age of 10 years and underwent tumor resection and gamma knife surgery was admitted for non-symptomatic severe hypernatremia. Although the sodium level was 173 mmol/L and serum osmolality was also high (371 mOsm/kg), the patient did not report increased thirst. Laboratory analysis revealed hypertonic dehydration and acute non-oliguric renal failure due to dehydration. Treatment was based on correction of hypernatremia with hydration and education about regular, periodic water ingestion. The patient's hypernatremia and acute non-oliguric renal failure resolved with controlled daily fluid intake. To our knowledge, this is the first report of decreased thirst sensation secondary to craniopharyngioma and tumor resection leading to severe hypernatremia and non-oliguric renal failure in an adolescent. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acute Kidney Injury/etiology* | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Craniopharyngioma/complications | - |
dc.subject.MESH | Craniopharyngioma/surgery* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypernatremia/complications* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Pituitary Neoplasms/complications | - |
dc.subject.MESH | Pituitary Neoplasms/surgery* | - |
dc.subject.MESH | Thirst/physiology* | - |
dc.title | Hypodipsic hypernatremia leading to reversible renal failure following surgery for craniopharyngioma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Ah Reum Kwon | - |
dc.contributor.googleauthor | Jung-Min Ann | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Hyun Wook Chae | - |
dc.contributor.googleauthor | Ho-Seong Kim | - |
dc.identifier.doi | 23426838 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00228 | - |
dc.contributor.localId | A01184 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A04026 | - |
dc.relation.journalcode | J01681 | - |
dc.identifier.eissn | 2191-0251 | - |
dc.identifier.pmid | 23426838 | - |
dc.identifier.url | http://www.degruyter.com/doi/10.1515/jpem-2012-0176 | - |
dc.subject.keyword | craniopharyngioma | - |
dc.subject.keyword | hypernatremia | - |
dc.subject.keyword | hypodipsia | - |
dc.subject.keyword | renal failure | - |
dc.contributor.alternativeName | Kwon, Ah Reum | - |
dc.contributor.alternativeName | Kim, Ho Seong | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.alternativeName | Chae, Hyun Wook | - |
dc.contributor.affiliatedAuthor | Kwon, Ah Reum | - |
dc.contributor.affiliatedAuthor | Kim, Ho Seong | - |
dc.contributor.affiliatedAuthor | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | Chae, Hyun Wook | - |
dc.citation.volume | 25 | - |
dc.citation.number | 9-10 | - |
dc.citation.startPage | 1027 | - |
dc.citation.endPage | 1030 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, Vol.25(9-10) : 1027-1030, 2012 | - |
dc.identifier.rimsid | 33290 | - |
dc.type.rims | ART | - |
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