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High incidence of rickets in extremely low birth weight infants with severe parenteral nutrition-associated cholestasis and bronchopulmonary dysplasiabronchopulmonary dysplasia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남궁란 | - |
dc.contributor.author | 박국인 | - |
dc.contributor.author | 박민수 | - |
dc.contributor.author | 은호선 | - |
dc.contributor.author | 이순민 | - |
dc.contributor.author | 이철 | - |
dc.date.accessioned | 2014-12-19T17:10:39Z | - |
dc.date.available | 2014-12-19T17:10:39Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90918 | - |
dc.description.abstract | Risk factors for rickets of prematurity have not been re-examined since introduction of high mineral formula, particularly in ELBW infants. We analyzed the incidence and the risk factors of rickets in extremely low birth weight (ELBW) infants. As a retrospective case-control study from 2004 to 2008, risk factors were analyzed in 24 patients with rickets versus 31 patients without. The frequency of rickets in ELBW infants was 24/55 (44%). Infants with rickets were diagnosed at 48.2 ± 16.1 days of age, and improved by 85.3 ± 25.3 days. By radiologic evaluation, 29% were grade 1 rickets, 58% grade 2 and 13% grade 3. In univariate analysis, infants with rickets had significantly higher incidence of patent ductus arteriosus, parenteral nutrition associated cholestasis (PNAC), severe PNAC and moderate/severe bronchopulmonary dysplasia (BPD). In multiple regression analysis, after adjustment for gestation and birth weight, rickets significantly correlated with severe PNAC and with moderate/severe BPD. Serum peak alkaline phosphatase levels were significantly elevated in rickets (P < 0.001). In ELBW infants, the incidence of rickets of prematurity remains high and the incidence of severe PNAC and moderate/severe BPD was significantly increased 18 and 3 times, respectively. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Alkaline Phosphatase/blood | - |
dc.subject.MESH | Birth Weight | - |
dc.subject.MESH | Bronchopulmonary Dysplasia/etiology* | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Cholestasis/etiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gestational Age | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infant, Extremely Low Birth Weight | - |
dc.subject.MESH | Infant, Newborn | - |
dc.subject.MESH | Infant, Premature | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Parenteral Nutrition/adverse effects* | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Regression Analysis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Rickets/diagnostic imaging | - |
dc.subject.MESH | Rickets/enzymology | - |
dc.subject.MESH | Rickets/epidemiology* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.title | High incidence of rickets in extremely low birth weight infants with severe parenteral nutrition-associated cholestasis and bronchopulmonary dysplasiabronchopulmonary dysplasia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Soon Min Lee | - |
dc.contributor.googleauthor | Ran Namgung | - |
dc.contributor.googleauthor | Min Soo Park | - |
dc.contributor.googleauthor | Ho Sun Eun | - |
dc.contributor.googleauthor | Kook In Park | - |
dc.contributor.googleauthor | Chul Lee | - |
dc.identifier.doi | 10.3346/jkms.2012.27.12.1552 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01241 | - |
dc.contributor.localId | A01438 | - |
dc.contributor.localId | A01468 | - |
dc.contributor.localId | A02635 | - |
dc.contributor.localId | A02905 | - |
dc.contributor.localId | A03253 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 23255857 | - |
dc.subject.keyword | Bronchopulmonary Dysplasia | - |
dc.subject.keyword | Cholestasis | - |
dc.subject.keyword | Infant, Extremely Low Birth Weight | - |
dc.subject.keyword | Rickets | - |
dc.subject.keyword | Risk Factors | - |
dc.contributor.alternativeName | Namgung, Ran | - |
dc.contributor.alternativeName | Park, Kook In | - |
dc.contributor.alternativeName | Park, Min Soo | - |
dc.contributor.alternativeName | Eun, Ho Seon | - |
dc.contributor.alternativeName | Lee, Soon Min | - |
dc.contributor.alternativeName | Lee, Chul | - |
dc.contributor.affiliatedAuthor | Namgung, Ran | - |
dc.contributor.affiliatedAuthor | Park, Kook In | - |
dc.contributor.affiliatedAuthor | Park, Min Soo | - |
dc.contributor.affiliatedAuthor | Eun, Ho Seon | - |
dc.contributor.affiliatedAuthor | Lee, Soon Min | - |
dc.contributor.affiliatedAuthor | Lee, Chul | - |
dc.citation.volume | 27 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1552 | - |
dc.citation.endPage | 1555 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.27(12) : 1552-1555, 2012 | - |
dc.identifier.rimsid | 33213 | - |
dc.type.rims | ART | - |
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