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Optical coherence tomography evaluation of in-stent restenotic lesions with visible microvessels

DC FieldValueLanguage
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author신동호-
dc.contributor.author장양수-
dc.date.accessioned2014-12-19T17:08:54Z-
dc.date.available2014-12-19T17:08:54Z-
dc.date.issued2012-
dc.identifier.issn1042-3931-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90865-
dc.description.abstractOBJECTIVE: We sought to evaluate the characteristics of in-stent restenosis (ISR) lesions with microvessels, detected by an optical coherence tomography (OCT). BACKGROUND: No sufficient in vivo data exist regarding microvessel characteristics in ISR lesions. METHODS: Among 78 ISR lesions (drug-eluting stent, n = 72; bare-metal stent, n = 6) in our OCT registry database, visible microvessels were detected in 21 (27%). Microvessels were defined as low backscattering structures <200 μm in diameter on OCT. Clinical, angiographic, and OCT findings were compared between lesions with and without microvessels. RESULTS: Lesions with microvessels had a larger reference vessel diameter (2.90 ± 0.47 mm vs 2.58 ± 0.42 mm; P=.009) and post-stent minimum lumen diameter (2.76 ± 0.29 mm vs 2.54 ± 0.39 mm; P=.033) than those without microvessels. From OCT findings at the segment with minimal lumen cross-sectional area (CSA), neointimal hyperplasia (NIH) CSA (5.4 ± 1.7 mm² vs 4.2 ± 2.1 mm²; P=.024) and percent NIH CSA (NIH CSA x 100/stent CSA) were significantly greater in lesions with microvessels (79 ± 12% vs 67 ± 16%; P=.001). On multivariate analysis, reference vessel diameter (odds ratio [OR], 4.64; 95% confidence interval [CI], 1.05-20.4; P=.043) and percent NIH CSA at the segment with minimal lumen CSA (OR, 1.06; 95% CI, 1.01-1.12; P=.021) were independent predictors of microvessels. From receiver operating characteristic analysis, the cut-off values of reference vessel diameter and percent NIH CSA predicting the presence of microvessels were 3.1 mm and 74%, respectively. CONCLUSIONS: Visible microvessels in ISR lesions might be associated with increased vessel size and extent of NIH.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF INVASIVE CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAngioplasty, Balloon, Coronary-
dc.subject.MESHCoronary Restenosis/pathology*-
dc.subject.MESHCoronary Stenosis/therapy-
dc.subject.MESHCoronary Vessels/pathology*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMicrovessels/pathology*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeointima/pathology-
dc.subject.MESHROC Curve-
dc.subject.MESHStents*-
dc.subject.MESHTomography, Optical Coherence/methods*-
dc.titleOptical coherence tomography evaluation of in-stent restenotic lesions with visible microvessels-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorDong-Ho Shin-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.identifier.doi22388303-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02097-
dc.contributor.localIdA03448-
dc.relation.journalcodeJ01467-
dc.identifier.eissn1557-2501-
dc.identifier.pmid22388303-
dc.identifier.urlhttp://www.invasivecardiology.com/articles/optical-coherence-tomography-evaluation-stent-restenotic-lesions-visible-microvessels-
dc.subject.keywordoptical coherence tomography-
dc.subject.keywordrestenosis-
dc.subject.keywordstent-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameShin, Dong Ho-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorShin, Dong Ho-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.citation.volume24-
dc.citation.number3-
dc.citation.startPage116-
dc.citation.endPage120-
dc.identifier.bibliographicCitationJOURNAL OF INVASIVE CARDIOLOGY, Vol.24(3) : 116-120, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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