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Bioactivity and mechanical properties of collagen composite membranes reinforced by chitosan and β-tricalcium phosphate

DC FieldValueLanguage
dc.contributor.author권재성-
dc.contributor.author김경남-
dc.contributor.author김광만-
dc.contributor.author이용근-
dc.date.accessioned2014-12-19T17:01:18Z-
dc.date.available2014-12-19T17:01:18Z-
dc.date.issued2012-
dc.identifier.issn1552-4973-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90630-
dc.description.abstractIn this study, we analyzed the effects of varying concentrations of chitosan (CS) and β-tricalcium phosphate [β-TCP, Ca(3)(PO(4))(2)] on the mechanical and cell-adhesion properties of a collagen (CG) matrix for use in guided bone regeneration (GBR). Three different CS concentrations (0.5, 1, and 2%) and five different contents of β-TCP (0, 17, 29, 38, and 44%) were investigated. The composite membranes were analyzed by scanning electron microscopy and cell-adhesion, flexural-strength, and tear-strength assays. The results show that the cell-adhesion and mechanical properties of the composite membranes improved with increasing β-TCP and CS contents, yielding suitable levels of the adhesion of cells and adequate mechanical stability to ensure successful GBR. The CS adhered to the microsized β-TCP, which was distributed uniformly in the composite membranes. The β-TCP and CS have no negative effect on the cell morphology, viability, and proliferation and possess good biocompatibility. This study demonstrates that β-TCP/CS/CG composite membranes are good candidates for GBR membranes in future applications.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleBioactivity and mechanical properties of collagen composite membranes reinforced by chitosan and β-tricalcium phosphate-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Dental Engineering (치과생체재료공학)-
dc.contributor.googleauthorSang-Bae Lee-
dc.contributor.googleauthorJae-Sung Kwon-
dc.contributor.googleauthorYong-Keun Lee-
dc.contributor.googleauthorKwang-Mahn Kim-
dc.contributor.googleauthorKyoung-Nam Kim-
dc.identifier.doi10.1002/jbm.b.32760-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00247-
dc.contributor.localIdA00292-
dc.contributor.localIdA00312-
dc.contributor.localIdA02976-
dc.relation.journalcodeJ01267-
dc.identifier.eissn1552-4981-
dc.identifier.pmidcollagen ; chitosan ; b-tricalcium phosphate ; GBR ; periodontal therapy-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/jbm.b.32760/abstract-
dc.subject.keywordcollagen-
dc.subject.keywordchitosan-
dc.subject.keywordb-tricalcium phosphate-
dc.subject.keywordGBR-
dc.subject.keywordperiodontal therapy-
dc.contributor.alternativeNameKwon, Jae Sung-
dc.contributor.alternativeNameKim, Kyoung Nam-
dc.contributor.alternativeNameKim, Kwang Mahn-
dc.contributor.alternativeNameLee, Yong Keun-
dc.contributor.affiliatedAuthorKwon, Jae Sung-
dc.contributor.affiliatedAuthorKim, Kyoung Nam-
dc.contributor.affiliatedAuthorKim, Kwang Mahn-
dc.contributor.affiliatedAuthorLee, Yong Keun-
dc.citation.volume100-
dc.citation.number7-
dc.citation.startPage1935-
dc.citation.endPage1942-
dc.identifier.bibliographicCitationJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol.100(7) : 1935-1942, 2012-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers

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