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Current Understanding of Mycobacterium abscessus Infection

Authors
 Go-Eun Choi ; Youngsuk Jo ; Sung Jae Shin 
Citation
 Journal of Bacteriology and Virology, Vol.42(1) : 17~28, 2012 
Journal Title
 Journal of Bacteriology and Virology 
ISSN
 1598-2467 
Issue Date
2012
Abstract
Mycobacterium abscessus belongs to a group of rapidly growing mycobacteria (RGM) that cause a broad spectrum of infections in humans. In addition, the association of M. abscessus with the cause of community- and hospital-acquired infections has been recently reported. In fact, M. abscessus is known to be the most drug-resistant mycobacterium and naturally resistant to first-line anti-tuberculous drugs, resulting in the limited therapeutic options and a high failure rate of treatment response. Three closely related species; M. abscessus (sensu stricto), M. bolletii, and M. massiliense are currently identified however, consensus on the naming of M. abscessus-related species has not been made to date. We herein discuss the advanced understanding of the virulence potentials and pathophysiological features of M. abscessus to establish novel therapeutic strategies for M. abscessus infection.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/90621
DOI
10.4167/jbv.2012.42.1.17
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Microbiology
Yonsei Authors
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