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Viral shedding of 2009 pandemic H1N1 and evaluation of quarantine recommendations

DC FieldValueLanguage
dc.contributor.author김창오-
dc.contributor.author최준용-
dc.contributor.author백지현-
dc.contributor.author최희경-
dc.contributor.author송영구-
dc.contributor.author한상훈-
dc.contributor.author신소연-
dc.contributor.author정석훈-
dc.contributor.author진범식-
dc.contributor.author진성준-
dc.contributor.author채윤태-
dc.contributor.author김준명-
dc.date.accessioned2014-12-19T17:00:11Z-
dc.date.available2014-12-19T17:00:11Z-
dc.date.issued2012-
dc.identifier.issn1344-6304-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90596-
dc.description.abstractPublic health authorities recommend that isolation precautions for influenza should be continued for 7 days after illness onset or until 24 h after the resolution of symptoms, whichever event lasts longer. However, little data are available regarding the duration of isolation for patients with 2009 pandemic H1N1 (pH1N1). We recruited patients with confirmed pH1N1 virus infection at a 2,000-bed tertiary care center. Influenza viral loads from oropharyngeal swab specimens were serially determined by reverse transcriptase quantitative polymerase chain reaction every other day, and the risk factors for prolonged viral shedding were investigated. To evaluate the current recommendations for isolation precautions, we measured the intervals between symptom onset and the last viral RNA detection, and that between the last viral RNA detection and the point at which the patient was symptom-free for 24 h. From November 2009 to January 2010, 26 patients were enrolled, and viral RNA was detected in more than half of the eligible patients (10 of 19, 52.6%) for ≥7 days after symptom onset. While evaluating the policy for lifting quarantine, we found that viral RNA was detected in 4 of 15 patients (26.7%) beyond the recommended duration of isolation. In conclusion, viral RNA was detected in a substantial proportion of hospitalized patients even when they fulfilled the recommended conditions for lifting quarantine, and we believe that more prudence is required in this aspect.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJAPANESE JOURNAL OF INFECTIOUS DISEASES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfluenza A Virus, H1N1 Subtype/isolation & purification*-
dc.subject.MESHInfluenza, Human/pathology-
dc.subject.MESHInfluenza, Human/virology*-
dc.subject.MESHLongitudinal Studies-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOropharynx/virology-
dc.subject.MESHQuarantine/methods*-
dc.subject.MESHReal-Time Polymerase Chain Reaction-
dc.subject.MESHTime Factors-
dc.subject.MESHViral Load-
dc.subject.MESHVirus Shedding*-
dc.titleViral shedding of 2009 pandemic H1N1 and evaluation of quarantine recommendations-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorBum Sik Chin-
dc.contributor.googleauthorYun Tae Chae-
dc.contributor.googleauthorHee Kyung Choi-
dc.contributor.googleauthorJi-Hyeon Baek-
dc.contributor.googleauthorSung Joon Jin-
dc.contributor.googleauthorSo Youn Shin-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorChan Oh Kim-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorSeok Hoon Jeong-
dc.contributor.googleauthorJune Myung Kim-
dc.identifier.doi22446115-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01044-
dc.contributor.localIdA04191-
dc.contributor.localIdA01839-
dc.contributor.localIdA04228-
dc.contributor.localIdA02037-
dc.contributor.localIdA04286-
dc.contributor.localIdA02116-
dc.contributor.localIdA03619-
dc.contributor.localIdA03981-
dc.contributor.localIdA03983-
dc.contributor.localIdA04022-
dc.contributor.localIdA00953-
dc.relation.journalcodeJ01208-
dc.identifier.eissn1884-2836-
dc.identifier.pmid22446115-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordAged, 80 and over-
dc.subject.keywordFemale-
dc.subject.keywordHumans-
dc.subject.keywordInfluenza A Virus, H1N1 Subtype/isolation & purification*-
dc.subject.keywordInfluenza, Human/pathology-
dc.subject.keywordInfluenza, Human/virology*-
dc.subject.keywordLongitudinal Studies-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordOropharynx/virology-
dc.subject.keywordQuarantine/methods*-
dc.subject.keywordReal-Time Polymerase Chain Reaction-
dc.subject.keywordTime Factors-
dc.subject.keywordViral Load-
dc.subject.keywordVirus Shedding*-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameBaek, Ji Hyeon-
dc.contributor.alternativeNameChoi, Hee Kyoung-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.alternativeNameShin, So Youn-
dc.contributor.alternativeNameJeong, Seok Hoon-
dc.contributor.alternativeNameChin, Bum Sik-
dc.contributor.alternativeNameJin, Sung Joon-
dc.contributor.alternativeNameChae, Yun Tae-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorBaek, Ji Hyeon-
dc.contributor.affiliatedAuthorChoi, Hee Kyoung-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorShin, So Youn-
dc.contributor.affiliatedAuthorJeong, Seok Hoon-
dc.contributor.affiliatedAuthorChin, Bum Sik-
dc.contributor.affiliatedAuthorJin, Sung Joon-
dc.contributor.affiliatedAuthorChae, Yun Tae-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.citation.volume65-
dc.citation.number2-
dc.citation.startPage105-
dc.citation.endPage110-
dc.identifier.bibliographicCitationJAPANESE JOURNAL OF INFECTIOUS DISEASES, Vol.65(2) : 105-110, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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