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The Rebleeding Risk and Prognostic Factors of Acute Hemorrhagic Rectal Ulcer
DC Field | Value | Language |
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dc.contributor.author | 김번 | - |
dc.contributor.author | 한민석 | - |
dc.contributor.author | 김원호 | - |
dc.contributor.author | 홍성필 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 박수정 | - |
dc.contributor.author | 신혜선 | - |
dc.contributor.author | 이동준 | - |
dc.contributor.author | 조동후 | - |
dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2014-12-19T16:59:10Z | - |
dc.date.available | 2014-12-19T16:59:10Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1598-9100 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90565 | - |
dc.description.abstract | Background/Aims: Acute hemorrhagic rectal ulcer (AHRU) is an important etiology of lower gastrointestinal bleeding in intensive care unit patients and hospital inpatients. Moreover, with increasing elderly populations, and improved survival in critically ill patients, the incidence of AHRU has increased. The aim of this study is to determine rebleeding risk and prognostic factors of AHRU patients. Methods: We retrospectively reviewed 32 patients with AHRU in Severance Hospital from February 2006 to October 2010, collected clinical data, and analyzed their association with the recurrence of bleeding and mortality of patients. Results: The mean age of patients was 65.5 years, and 27 patients (84.4%) showed Eastern Cooperative Oncology Group performance status 3-4. Nineteen patients (59.4%) had recurrent bleeding. Hypoalbuminemia (≤2.5 g/dL) was a risk factor of rebleeding in univariate and multivariate analysis. For patients with chronic liver disease, hypoalbuminemia (≤2.5 g/dL), renal dysfunction (>2 mg/dL) and thrombocytopenia (<150,000/μL) showed relatively earlier rebleeding than those without (P=0.007, P=0.009, P=0.027 and P=0.043, respectively). The endoscopic hemostasis at the first bleeding event was associated with lower early rebleeding rate (P=0.048). In univariate analysis, chronic liver disease, hypoalbuminemia (≤2.5 g/dL) and the prolongation of activated partial thromboplastin time (>40 seconds) increased mortality (P=0.028, P=0.008 and P=0.027, respectively) and the patients with rebleeding showed a tendency toward higher mortality, compared to those without (57.9% vs. 23.1%, P=0.051). Conclusions: In AHRU patients, hypoalbuminemia was a risk factor of rebleeding, and chronic liver disease, hypoalbuminemia, renal dysfunction, thrombocytopenia and no endoscopic treatment at the first bleeding event was correlated with relatively earlier rebleeding. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 343~349 | - |
dc.relation.isPartOf | INTESTINAL RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The Rebleeding Risk and Prognostic Factors of Acute Hemorrhagic Rectal Ulcer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Bun Kim | - |
dc.contributor.googleauthor | Min Seok Han | - |
dc.contributor.googleauthor | Dong Hoo Joh | - |
dc.contributor.googleauthor | Dong Jun Lee | - |
dc.contributor.googleauthor | Hye Sun Shin | - |
dc.contributor.googleauthor | Soo Jung Park | - |
dc.contributor.googleauthor | Sung Pil Hong | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Tae Il Kim | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.identifier.doi | 10.5217/ir.2012.10.4.343 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00486 | - |
dc.contributor.localId | A04281 | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A04404 | - |
dc.contributor.localId | A01079 | - |
dc.contributor.localId | A02182 | - |
dc.contributor.localId | A02733 | - |
dc.contributor.localId | A03815 | - |
dc.contributor.localId | A01539 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J01182 | - |
dc.identifier.eissn | 1598-9100 | - |
dc.identifier.pmid | Rectum ; Ulcer ; Gastrointestinal Hemorrhage ; Prognosis | - |
dc.subject.keyword | Rectum | - |
dc.subject.keyword | Ulcer | - |
dc.subject.keyword | Gastrointestinal Hemorrhage | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Kim, Bun | - |
dc.contributor.alternativeName | Han, Min Seok | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.alternativeName | Hong, Sung Pil | - |
dc.contributor.alternativeName | Kim, Tae Il | - |
dc.contributor.alternativeName | Park, Soo Jung | - |
dc.contributor.alternativeName | Shin, Hye Sun | - |
dc.contributor.alternativeName | Lee, Dong Jun | - |
dc.contributor.alternativeName | Joh, Dong Hoo | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | Kim, Bun | - |
dc.contributor.affiliatedAuthor | Han, Min Seok | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Hong, Sung Pil | - |
dc.contributor.affiliatedAuthor | Kim, Tae Il | - |
dc.contributor.affiliatedAuthor | Shin, Hye Sun | - |
dc.contributor.affiliatedAuthor | Lee, Dong Jun | - |
dc.contributor.affiliatedAuthor | Joh, Dong Hoo | - |
dc.contributor.affiliatedAuthor | Park, Soo Jung | - |
dc.contributor.affiliatedAuthor | Cheon, Jae Hee | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 343 | - |
dc.citation.endPage | 349 | - |
dc.identifier.bibliographicCitation | INTESTINAL RESEARCH, Vol.10(4) : 343-349, 2012 | - |
dc.identifier.rimsid | 32837 | - |
dc.type.rims | ART | - |
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