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Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation.

DC Field Value Language
dc.contributor.author고영국-
dc.contributor.author김동민-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.date.accessioned2014-12-19T16:55:42Z-
dc.date.available2014-12-19T16:55:42Z-
dc.date.issued2012-
dc.identifier.issn1569-5794-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90455-
dc.description.abstractPrevious optical coherence tomography (OCT) studies in patients with drug-eluting stents (DESs)-related very late stent thrombosis (VLST) were scarce. Therefore, we investigated OCT findings of VLST after implantation of DESs. Using OCT, we analyzed the status of stent struts and neointimal characteristics in 18 patients who developed VLST after DES implantation. These results were compared to those in 57 patients with neointimal hyperplasia causing >40% diameter stenosis. Lipid-laden neointima was defined as a region with marked signal attenuation and a diffuse border. Four (22.2%) of 18 patients with VLST had ruptured and lipid-laden neointima inside DESs without uncovered or malapposed stent struts. In the remaining 14 patients who developed VLST without neointimal rupture, uncovered and malapposed struts were observed in nine and seven patients, respectively, and lipid-laden neointima in four patients. Lipid-laden neointima was more frequently observed in four patients with neointimal rupture than in 14 patients without neointimal rupture (100% vs. 28.6%, respectively, P = 0.023). Of 57 patients with neointimal hyperplasia, eight (14.0%) had lipid-laden neointima. Time to OCT study after DES implantation was significantly longer in the eight patients with lipid-laden neointima than in 49 patients without lipid-laden neointima (45.5 ± 17.7 months vs. 11.7 ± 7.2 months, respectively, P < 0.001). Lipid-laden neointima was detected in some patients with neointimal hyperplasia > 1 year after DES implantation. In addition to uncovered or malapposed struts, rupture of lipid-laden neointima inside DESs was identified in some patients with DES-related VLST.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAngioplasty, Balloon, Coronary/adverse effects-
dc.subject.MESHAngioplasty, Balloon, Coronary/instrumentation*-
dc.subject.MESHCardiovascular Agents/administration & dosage-
dc.subject.MESHChi-Square Distribution-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Artery Disease/metabolism-
dc.subject.MESHCoronary Artery Disease/pathology-
dc.subject.MESHCoronary Artery Disease/therapy*-
dc.subject.MESHCoronary Thrombosis/etiology-
dc.subject.MESHCoronary Thrombosis/metabolism-
dc.subject.MESHCoronary Thrombosis/pathology*-
dc.subject.MESHCoronary Vessels/metabolism-
dc.subject.MESHCoronary Vessels/pathology*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHEverolimus-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHyperplasia-
dc.subject.MESHLipid Metabolism-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeointima/metabolism-
dc.subject.MESHNeointima/pathology*-
dc.subject.MESHPaclitaxel/administration & dosage-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProsthesis Design-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Assessment-
dc.subject.MESHRisk Factors-
dc.subject.MESHSirolimus/administration & dosage-
dc.subject.MESHSirolimus/analogs & derivatives-
dc.subject.MESHTime Factors-
dc.subject.MESHTomography, Optical Coherence*-
dc.subject.MESHTreatment Outcome-
dc.titleOptical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDong-Min Kim-
dc.contributor.googleauthorJin Man Cho-
dc.contributor.googleauthorSo Yeon Choi-
dc.contributor.googleauthorJung Han Yoon-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.identifier.doi21656060-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00127-
dc.contributor.localIdA00401-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.relation.journalcodeJ01094-
dc.identifier.eissn1875-8312-
dc.identifier.pmid21656060-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10554-011-9905-3-
dc.subject.keywordOptical coherence tomography-
dc.subject.keywordStent-
dc.subject.keywordThrombosis-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Dong Min-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Dong Min-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.citation.volume28-
dc.citation.number4-
dc.citation.startPage715-
dc.citation.endPage723-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.28(4) : 715-723, 2012-
dc.identifier.rimsid32773-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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