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Major determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation.

DC FieldValueLanguage
dc.contributor.author홍명기-
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author오창명-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.date.accessioned2014-12-19T16:55:40Z-
dc.date.available2014-12-19T16:55:40Z-
dc.date.issued2012-
dc.identifier.issn1569-5794-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90454-
dc.description.abstractThere have been little data regarding major determinants for the uncovered stent struts after drug-eluting stent (DES) implantation on optical coherence tomography (OCT). We investigated the major determinants of incomplete neointimal coverage of DES struts on OCT after implantation in a large cohort of patients. A total of 261 patients with 279 lesions who were treated with various DESs were selected from the OCT registry database. The lesions were divided into two groups based on the ratio of uncovered struts to total struts in all OCT cross-sections; an uncovered group (highest quartile with % uncovered struts ≥5.4%, n = 70), and covered group (the remaining lower quartiles with % uncovered struts <5.4%, n = 209). The uncovered group was more likely to have complex lesions, smaller reference vessel and stent diameter, and longer stent, more use of sirolimus-eluting stents, and less use of zotarolimus-eluting stents compared with the covered group. Of these variables, the most significant determinant of uncovered stent struts was DES type (odds ratio [OR] = 2.75, 95% confidence interval [CI] = 1.94-3.89, P < 0.001). The use of sirolimus-eluting stents (OR = 2.44, 95% CI, 1.15-5.47, P = 0.023) and zotarolimus-eluting stents (OR = 0.02, 95% CI = 0.01-0.25, P = 0.002) were the only significant risk and protective factors for uncovered stent struts, respectively. This study demonstrated that DES type might be associated with the most important determinants of uncovered struts compared to any other clinical or angiographic factor.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAnalysis of Variance-
dc.subject.MESHAngioplasty, Balloon, Coronary/adverse effects-
dc.subject.MESHAngioplasty, Balloon, Coronary/instrumentation*-
dc.subject.MESHCardiovascular Agents/administration & dosage-
dc.subject.MESHCoronary Artery Disease/pathology-
dc.subject.MESHCoronary Artery Disease/therapy*-
dc.subject.MESHCoronary Restenosis/etiology-
dc.subject.MESHCoronary Restenosis/pathology-
dc.subject.MESHCoronary Restenosis/prevention & control-
dc.subject.MESHCoronary Thrombosis/etiology-
dc.subject.MESHCoronary Thrombosis/pathology-
dc.subject.MESHCoronary Thrombosis/prevention & control-
dc.subject.MESHCoronary Vessels/pathology*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHEverolimus-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOdds Ratio-
dc.subject.MESHPaclitaxel/administration & dosage-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHProsthesis Design-
dc.subject.MESHRegistries-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Assessment-
dc.subject.MESHRisk Factors-
dc.subject.MESHSirolimus/administration & dosage-
dc.subject.MESHSirolimus/analogs & derivatives-
dc.subject.MESHTime Factors-
dc.subject.MESHTomography, Optical Coherence*-
dc.subject.MESHTreatment Outcome-
dc.titleMajor determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorChangmyung Oh-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.identifier.doi21626042-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04391-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02405-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.relation.journalcodeJ01094-
dc.identifier.eissn1875-8312-
dc.identifier.pmid21626042-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10554-011-9896-0-
dc.subject.keywordOptical coherence tomography-
dc.subject.keywordStent-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameOh, Chang Myung-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorOh, Chang Myung-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.citation.volume28-
dc.citation.number4-
dc.citation.startPage705-
dc.citation.endPage714-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.28(4) : 705-714, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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