Cited 19 times in
Incidence and 30-day mortality of peptic ulcer bleeding in Korea
DC Field | Value | Language |
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dc.contributor.author | 김지현 | - |
dc.date.accessioned | 2014-12-19T16:47:25Z | - |
dc.date.available | 2014-12-19T16:47:25Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0954-691X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90198 | - |
dc.description.abstract | OBJECTIVES: To estimate the rates of peptic ulcer bleeding (PUB) incidence and the association of demographic factors with 30-day mortality after PUB. METHODS: Diagnostic algorithms for PUB were derived and validated on the basis of 115 true PUB patients at one tertiary hospital in 2005, followed by estimation of age-specific PUB incidence and 30-day mortality rates, using the Korean National Health Insurance claim database. A Cox proportional hazard model was used to determine the impact of demographic factors on the 30-day mortality rate ratio (MRR) after PUB. RESULTS: The diagnostic algorithm showed 89 and 88% positive predictive value and sensitivity, respectively. On the basis of this algorithm, the rate of PUB incidence was 22.1 per 100 000 during 2006-2007 and the age-specific incidence rate increased with advanced age. This incidence rate was more than three times higher among men than women. Among 21 107 PUB patients, the overall 30-day mortality rate was 2.15%, but it ranged from 0.83% for patients younger than 60 years to 7.65% for patients older than 80 years. The adjusted 30-day mortality rate ratio for patients older than 80 was 8.13 (95% confidence interval 6.10-10.8) compared with those younger than 60 and 7.09 (95% confidence interval 2.78-4.51) for patients with a high level of comorbidity compared with a low level of comorbidity. CONCLUSION: PUB incidence was higher among men and increased with advanced age. Increased 30-day mortality was observed in association with increasing age, after adjusting for comorbidity. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Distribution | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Algorithms | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospitalization/statistics & numerical data | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Peptic Ulcer Hemorrhage/diagnosis | - |
dc.subject.MESH | Peptic Ulcer Hemorrhage/epidemiology* | - |
dc.subject.MESH | Peptic Ulcer Hemorrhage/mortality | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sex Distribution | - |
dc.title | Incidence and 30-day mortality of peptic ulcer bleeding in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Bae, Seung Jin | - |
dc.contributor.googleauthor | Kim, Nayoung | - |
dc.contributor.googleauthor | Kang, Jung Mook | - |
dc.contributor.googleauthor | Kim, Dong-Sook | - |
dc.contributor.googleauthor | Kim, Kyoung-Min | - |
dc.contributor.googleauthor | Cho, Yu Kyung | - |
dc.contributor.googleauthor | Kim, Jie-Hyun | - |
dc.contributor.googleauthor | Jung, Sung Woo | - |
dc.contributor.googleauthor | Shim, Ki-Nam | - |
dc.identifier.doi | 10.1097/MEG.0b013e3283525a56 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00996 | - |
dc.relation.journalcode | J00821 | - |
dc.identifier.eissn | 1473-5687 | - |
dc.identifier.pmid | 22441511 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00042737-201206000-00010&LSLINK=80&D=ovft | - |
dc.subject.keyword | bleeding | - |
dc.subject.keyword | incidence | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | peptic ulcer | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.citation.volume | 24 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 675 | - |
dc.citation.endPage | 682 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol.24(6) : 675-682, 2012 | - |
dc.identifier.rimsid | 32421 | - |
dc.type.rims | ART | - |
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