Cited 0 times in
Localization of ictal onset zones in Lennox-Gastaut syndrome (LGS) based on information theoretical time delay analysis of intracranial electroencephalography (iEEG).
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강훈철 | - |
dc.contributor.author | 김흥동 | - |
dc.date.accessioned | 2014-12-19T16:46:41Z | - |
dc.date.available | 2014-12-19T16:46:41Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0920-1211 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90175 | - |
dc.description.abstract | Precise localization of ictal onset zones is of great clinical importance for successful surgery in patients with intractable drug-resistant epilepsy. Time delay analysis has been one of the most reliable and most widely used computational electroencephalogram (EEG) analysis methods for localizing ictal onset zones. However, the majority of previous studies have only been applied to the localization of ictal onset zones in focal epilepsy. In the present study, we analyzed intracranial EEG (iEEG) recordings acquired from patients with Lennox-Gaustaut syndrome (LGS), which is a type of intractable, pediatric, secondary generalized epilepsies with bilaterally synchronous ictal epileptiform discharges. To estimate the ictal onset zones from ictal iEEG recordings, we estimated time delays among iEEG signals based on the information theoretical approach. The results of the time delay analysis applied to the iEEG data of four successfully treated LGS patients corresponded well with the surgical resection areas identified by experienced epileptologists and multiple neuroimaging modalities, suggesting that the time delay analysis may provide useful information on the precise locations of ictal onset zones prior to epilepsy surgery in LGS patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | EPILEPSY RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Electroencephalography/methods* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intellectual Disability/diagnosis* | - |
dc.subject.MESH | Intellectual Disability/physiopathology* | - |
dc.subject.MESH | Intellectual Disability/surgery | - |
dc.subject.MESH | Lennox Gastaut Syndrome | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Spasms, Infantile/diagnosis* | - |
dc.subject.MESH | Spasms, Infantile/physiopathology* | - |
dc.subject.MESH | Spasms, Infantile/surgery | - |
dc.subject.MESH | Time Factors | - |
dc.title | Localization of ictal onset zones in Lennox-Gastaut syndrome (LGS) based on information theoretical time delay analysis of intracranial electroencephalography (iEEG). | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Jae-Hyun Cho | - |
dc.contributor.googleauthor | Hoon-Chul Kang | - |
dc.contributor.googleauthor | Young-Jin Jung | - |
dc.contributor.googleauthor | Yong-Ho Lee | - |
dc.contributor.googleauthor | Ki-Young Jung | - |
dc.contributor.googleauthor | Heung Dong Kim | - |
dc.contributor.googleauthor | Chang-Hwan Im | - |
dc.identifier.doi | 22071552 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00102 | - |
dc.contributor.localId | A01208 | - |
dc.relation.journalcode | J00796 | - |
dc.identifier.eissn | 1872-6844 | - |
dc.identifier.pmid | 22071552 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0920121111003329 | - |
dc.subject.keyword | Ictal onset zones | - |
dc.subject.keyword | Intracranial electroencephalography (iEEG) | - |
dc.subject.keyword | Lennox–Gastaut syndrome (LGS) | - |
dc.subject.keyword | Mutual information | - |
dc.subject.keyword | Secondary generalized epilepsy | - |
dc.subject.keyword | Time delay estimation | - |
dc.contributor.alternativeName | Kang, Hoon Chul | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Kang, Hoon Chul | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.citation.volume | 99 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 78 | - |
dc.citation.endPage | 86 | - |
dc.identifier.bibliographicCitation | EPILEPSY RESEARCH, Vol.99(1-2) : 78-86, 2012 | - |
dc.identifier.rimsid | 32408 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.