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Second opinion in thyroid fine-needle aspiration biopsy by the Bethesda system.

 Jae Hyun Park  ;  Hyun Ki Kim  ;  Sang-Wook Kang  ;  Jong Ju Jeong  ;  Kee-Hyun Nam  ;  Woong-Youn Chung  ;  Cheong Soo Park 
 ENDOCRINE JOURNAL, Vol.59(3) : 205-212, 2012 
Journal Title
Issue Date
Adolescent ; Adult ; Aged ; Biopsy, Fine-Needle* ; Carcinoma, Medullary/diagnosis* ; Carcinoma, Medullary/surgery ; Carcinoma, Papillary/diagnosis* ; Carcinoma, Papillary/surgery ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Referral and Consultation* ; Retrospective Studies ; Thyroid Gland/pathology* ; Thyroid Gland/surgery ; Thyroid Neoplasms/diagnosis* ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/surgery ; Thyroid Nodule/diagnosis* ; Thyroid Nodule/pathology ; Thyroid Nodule/surgery ; Thyroidectomy
Second opinion ; Thyroid fine-needle aspiration biopsy ; Bethesda System
The present study was designed to determine the impact of secondary review of thyroid fine-needle aspiration (FNA) biopsy on surgical management. A retrospective review of patients referred to our institution with a thyroid FNA biopsy was conducted. Cytologic diagnoses from the report at our center and the referring institution were re-categorized by the Bethesda System for Reporting Thyroid Cytopathology. The rate of diagnostic disagreement was evaluated between Primary Diagnosis (PD) and Second Opinion Diagnosis (SOD), and the clinicopathologic correlations and the number of cases that prompted changes in treatment as a result of diagnostic disagreement were analyzed. 1499 patients meeting our study criteria were enrolled in this study. Diagnostic disagreement comprised 394 cases (26.3%). In the case of diagnostic disagreement, SOD was supported on clinicopathologic follow-up in 271 cases (68.8%), of which a change in management was made in 54 (13.7%) cases, and PD was supported in 93 (23.6%) cases, of which a change in management was made in 13 (3.3%) cases. By the second opinion, 65 (4.5%) patients received proper management, and 14 (1.0%) patients received superfluous management. Wide use of secondary cytopathologic review of thyroid FNA specimens from referring institutions was recommended.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Sang Wook(강상욱) ORCID logo https://orcid.org/0000-0001-5355-833X
Kim, Hyunki(김현기) ORCID logo https://orcid.org/0000-0003-2292-5584
Nam, Kee Hyun(남기현) ORCID logo https://orcid.org/0000-0002-6852-1190
Park, Jae Hyun(박재현)
Park, Cheong Soo(박정수)
Chung, Woong Youn(정웅윤)
Jeong, Jong Ju(정종주) ORCID logo https://orcid.org/0000-0002-4155-6035
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