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Comparison of vascular remodeling in patients treated with sirolimus-versus zotarolimus-eluting stent following acute myocardial infarction.

DC FieldValueLanguage
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author신동호-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author강기운-
dc.contributor.author고영국-
dc.date.accessioned2014-12-19T16:41:37Z-
dc.date.available2014-12-19T16:41:37Z-
dc.date.issued2012-
dc.identifier.issn0160-9289-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90012-
dc.description.abstractBACKGROUND: The differences in the vascular response to stent implantation or in the incidence of late acquired stent malapposition among different types of drug-eluting stents are not well known in patients with acute myocardial infarction (MI). HYPOTHESIS: The pattern of vascular remodeling and degree of neointimal proliferation were different depending on the different types of drug-eluting stents. METHODS: This study used intravascular ultrasound (IVUS) to investigate vascular remodeling in patients treated with implantation of sirolimus-eluting stents (SESs) vs zotarolimus-eluting stents (ZESs) following acute MI. The study population consisted of 100 patients with acute MI who were treated either with SES (n = 41) or ZES (n = 59) and underwent both poststenting and 9-month follow-up IVUS examination. Serial vascular changes surrounding stented segments were compared between SES- and ZES-treated lesions. RESULTS: Percentage of neointimal volume obstruction at follow-up was significantly smaller in SES-treated compared to ZES-treated lesions (2.8 ± 7.1% vs 18.1 ± 15.7%, respectively; P < 0.001). However, positive vascular remodeling, which was defined as greater than 10% increase in external elastic membrane volume index (31.7% vs 10.2%, respectively, P = 0.007), and late acquired stent malapposition (12.0% vs 0%, respectively, P = 0.006 ) occurred more frequently in SES-treated than in ZES-treated lesions. CONCLUSIONS: The pattern of vascular remodeling, including positive remodeling, late acquired stent malapposition, and degree of neointimal proliferation might be different depending on the different types of drug-eluting stents in patients with acute MI.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCLINICAL CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAngioplasty, Balloon, Coronary-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Vessels/pathology*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMyocardial Infarction/pathology-
dc.subject.MESHMyocardial Infarction/therapy*-
dc.subject.MESHNeointima/pathology*-
dc.subject.MESHSirolimus/analogs & derivatives*-
dc.subject.MESHSirolimus/therapeutic use*-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUltrasonography, Interventional-
dc.titleComparison of vascular remodeling in patients treated with sirolimus-versus zotarolimus-eluting stent following acute myocardial infarction.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorKi-Woon Kang-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDong-Ho Shin-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.identifier.doi22161864-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02097-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA00007-
dc.contributor.localIdA00127-
dc.relation.journalcodeJ00565-
dc.identifier.eissn1932-8737-
dc.identifier.pmid22161864-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/clc.20988/abstract-
dc.subject.keywordAngioplasty, Balloon, Coronary-
dc.subject.keywordCoronary Angiography-
dc.subject.keywordCoronary Vessels/pathology*-
dc.subject.keywordDrug-Eluting Stents*-
dc.subject.keywordFemale-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordMale-
dc.subject.keywordMyocardial Infarction/pathology-
dc.subject.keywordMyocardial Infarction/therapy*-
dc.subject.keywordNeointima/pathology*-
dc.subject.keywordSirolimus/analogs & derivatives*-
dc.subject.keywordSirolimus/therapeutic use*-
dc.subject.keywordTreatment Outcome-
dc.subject.keywordUltrasonography, Interventional-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameShin, Dong Ho-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameKang, Ki Woon-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorShin, Dong Ho-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKang, Ki Woon-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.citation.volume35-
dc.citation.number1-
dc.citation.startPage49-
dc.citation.endPage54-
dc.identifier.bibliographicCitationCLINICAL CARDIOLOGY, Vol.35(1) : 49-54, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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