Cited 36 times in
Red blood cell distribution width predicts early mortality in patients with acute dyspnea
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 오재원 | - |
dc.contributor.author | 원호연 | - |
dc.contributor.author | 윤종찬 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 김수영 | - |
dc.date.accessioned | 2014-12-19T16:40:38Z | - |
dc.date.available | 2014-12-19T16:40:38Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89980 | - |
dc.description.abstract | BACKGROUND: Red blood cell distribution width (RDW) has been shown to predict clinical outcomes in cardiovascular diseases. We studied whether RDW is useful to predict early mortality in patients with acute dyspnea at an emergency department (ED). METHODS: We retrospectively analyzed 907 patients with acute dyspnea who visited the ED from January 2009 to May 2009. Primary outcome was 30-day mortality. RESULTS: Acute decompensated heart failure (29.9%) was the most common adjudicated discharge diagnosis followed by cancer (14.8%) and pneumonia (12.5%). There was a stepwise increase of 30-day mortality risk from lowest (RDW<12.9%) to highest (RDW>14.3%) RDW tertiles (1.4% vs. 8.3% vs. 18.3%; log-rank P<0.001). In multivariate Cox hazard analysis, RDW was an independent predictor of 30-day mortality after adjusting for other risk factors (HR 1.23; 95% CI 1.11-1.36; P<0.001). Adding RDW to conventional clinical predictors significantly improved prediction for 30-day mortality as measured by the area under the ROC curve (AUC, from 0.873 to 0.885; P=0.023) and the net reclassification improvement (NRI=14.1%; P<0.001)/integrated discrimination improvement (IDI=0.038; P=0.006). CONCLUSIONS: Our findings suggest that RDW measured at ED is an independent and additive predictor of early mortality in patients with acute dyspnea. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acute Disease | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Dyspnea/blood* | - |
dc.subject.MESH | Dyspnea/mortality* | - |
dc.subject.MESH | Erythrocyte Indices* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Failure/mortality | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasms/diagnosis | - |
dc.subject.MESH | Pneumonia/diagnosis | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Time Factors | - |
dc.title | Red blood cell distribution width predicts early mortality in patients with acute dyspnea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Namki Hong | - |
dc.contributor.googleauthor | Jaewon Oh | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Soo-Young Kim | - |
dc.contributor.googleauthor | Hoyoun Won | - |
dc.contributor.googleauthor | Jong Chan Youn | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1016/j.cca.2012.02.024 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A02448 | - |
dc.contributor.localId | A02600 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A02395 | - |
dc.contributor.localId | A04388 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 22406179 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009898112001064 | - |
dc.subject.keyword | Dyspnea | - |
dc.subject.keyword | Mortality | - |
dc.subject.keyword | Red blood cell distribution width | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Oh, Jae Won | - |
dc.contributor.alternativeName | Won, Ho Youn | - |
dc.contributor.alternativeName | Youn, Jong Chan | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Won, Ho Youn | - |
dc.contributor.affiliatedAuthor | Youn, Jong Chan | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Oh, Jae Won | - |
dc.contributor.affiliatedAuthor | Hong, Namki | - |
dc.citation.volume | 413 | - |
dc.citation.number | 11-12 | - |
dc.citation.startPage | 992 | - |
dc.citation.endPage | 997 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.413(11-12) : 992-997, 2012 | - |
dc.identifier.rimsid | 32015 | - |
dc.type.rims | ART | - |
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