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Treatment performance measures affect clinical outcomes in patients with acute systolic heart failure: report from the Korean Heart Failure Registry.

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dc.contributor.author강석민-
dc.date.accessioned2014-12-19T16:40:15Z-
dc.date.available2014-12-19T16:40:15Z-
dc.date.issued2012-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89968-
dc.description.abstractBACKGROUND: There is a paucity of data on the effects of adherence to treatment on outcomes for patients with acute heart failure (HF) in Korea. We used HF performance measures to evaluate overall adherence and whether this affects clinical outcomes. METHODS AND RESULTS: Among 3,466 patients in the Korean Heart Failure Registry, 1,527 patients with left ventricular systolic dysfunction (LVSD) who survived hospitalization were evaluated. Modified validated performance measures were defined as follows: use at discharge of angiotensin-converting enzyme inhibitor (ACEI), angiotensin-receptor II blocker (ARB), β-blocker or aldosterone receptor antagonist. Adherence to performance measures were as follows: ACEI or ARB at discharge, 68.0%; β-blocker at discharge, 40.9%; aldosterone receptor antagonist at discharge, 37.5%. On multivariate analysis, adherence to the measure of ACEI or ARB use at discharge was significantly associated with mortality (odds ratio (OR), 0.344; 95% confidence interval (CI), 0.123-0.964), readmission (OR, 0.180; 95%CI, 0.062-0.522) and mortality/readmission (OR, 0.297; 95%CI, 0.125-0.707) at 60 days and that for β-blocker with mortality (OR, 0.337; 95%CI, 0.147-0.774) at 1 year. CONCLUSIONS: For patients with LVSD in Korea, adherence to treatment performance measures, including prescription of an ACEI/ARB and β-blocker use at discharge, is associated with improved clinical outcomes.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcute Disease-
dc.subject.MESHAdrenergic beta-Antagonists/therapeutic use-
dc.subject.MESHAdvance Directive Adherence-
dc.subject.MESHAged-
dc.subject.MESHAngiotensin-Converting Enzyme Inhibitors/therapeutic use-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHeart Failure, Systolic/mortality*-
dc.subject.MESHHeart Failure, Systolic/therapy*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRegistries*-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTask Performance and Analysis-
dc.subject.MESHSubstances-
dc.titleTreatment performance measures affect clinical outcomes in patients with acute systolic heart failure: report from the Korean Heart Failure Registry.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorYoung Jin Youn-
dc.contributor.googleauthorByung-Su Yoo-
dc.contributor.googleauthorJun-Won Lee-
dc.contributor.googleauthorJang-Young Kim-
dc.contributor.googleauthorSeong Woo Han-
dc.contributor.googleauthorEun-Seok Jeon-
dc.contributor.googleauthorMyeong-Chan Cho-
dc.contributor.googleauthorJae-Joong Kim-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorShung Chull Chae-
dc.contributor.googleauthorByung-Hee Oh-
dc.contributor.googleauthorDong-Ju Choi-
dc.contributor.googleauthorMyung Mook Lee-
dc.contributor.googleauthorKyu-Hyung Ryu-
dc.identifier.doi22343195-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00037-
dc.relation.journalcodeJ00534-
dc.identifier.eissn1347-4820-
dc.identifier.pmid22343195-
dc.subject.keywordLeft ventricular systolic dysfunction-
dc.subject.keywordMortality-
dc.subject.keywordPerformance measures-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.citation.volume76-
dc.citation.number5-
dc.citation.startPage1151-
dc.citation.endPage1158-
dc.identifier.bibliographicCitationCIRCULATION JOURNAL, Vol.76(5) : 1151-1158, 2012-
dc.identifier.rimsid32007-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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