2 270

Cited 0 times in

Multifocality in early gastric cancer does not increase the risk of lymph node metastasis in a single-center study

DC FieldValueLanguage
dc.contributor.author이용찬-
dc.contributor.author김충배-
dc.contributor.author조재희-
dc.contributor.author김현기-
dc.contributor.author형우진-
dc.contributor.author김희만-
dc.contributor.author노성훈-
dc.contributor.author박경호-
dc.contributor.author송시영-
dc.contributor.author윤영훈-
dc.contributor.author이상길-
dc.date.accessioned2014-12-19T16:26:50Z-
dc.date.available2014-12-19T16:26:50Z-
dc.date.issued2012-
dc.identifier.issn1068-9265-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89543-
dc.description.abstractBACKGROUND: The multifocality rate of EGC ranges from 4 to 20%, but there are few data regarding both lymph node metastasis and feasibility of the endoscopic treatment. We investigated the risk of lymph node metastasis with the purpose to evaluate the potential for endoscopic treatment in patients with multifocal EGC. METHODS: We retrospectively reviewed the medical records of patients who underwent radical gastrectomy to treat EGC between January 2001 and December 2007 at Severance Hospital, Seoul, Korea. Synchronous multifocal EGC was defined as EGC having two or more malignant foci, whereas solitary EGC was defined as EGC having single focus. RESULTS: Of 1,693 patients, 55 (3.2%) were diagnosed with synchronous multifocal EGC. The rates of lymph node metastasis were 12.7% in synchronous multifocal EGC and 10% in solitary EGC. In the multivariate analysis, synchronous multifocal EGC was not associated with lymph node metastasis (odds ratio, 1.1; 95% confidence interval, 0.4-2.7) compared with solitary EGC. In a subgroup analysis of 55 patients with synchronous multifocal EGC, older age (≥65 years) and lymphovascular invasion were associated with lymph node metastasis. In synchronous multifocal EGC, none of the cases had lymph node metastasis in major and minor lesions representing mucosal cancer without lymphovascular invasion. CONCLUSIONS: Synchronous multifocality of EGC does not increase the risk of lymph node metastasis compared with solitary EGC. Therefore, endoscopic treatment can be planned when major and minor lesions are predicted to represent mucosal cancer without lymphovascular invasion.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfANNALS OF SURGICAL ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/mortality-
dc.subject.MESHAdenocarcinoma/pathology-
dc.subject.MESHAdenocarcinoma/secondary*-
dc.subject.MESHCarcinoma, Signet Ring Cell/mortality-
dc.subject.MESHCarcinoma, Signet Ring Cell/pathology-
dc.subject.MESHCarcinoma, Signet Ring Cell/secondary*-
dc.subject.MESHFemale-
dc.subject.MESHGastrectomy-
dc.subject.MESHHumans-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHStomach Neoplasms/mortality-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHSurvival Rate-
dc.titleMultifocality in early gastric cancer does not increase the risk of lymph node metastasis in a single-center study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHee Man Kim-
dc.contributor.googleauthorHyun Ki Kim-
dc.contributor.googleauthorSang Kil Lee-
dc.contributor.googleauthorJae Hee Cho-
dc.contributor.googleauthorKyung Ho Pak-
dc.contributor.googleauthorWoo Jin Hyung-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorChoong Bai Kim-
dc.contributor.googleauthorYong Chan Lee-
dc.contributor.googleauthorSi Young Song-
dc.contributor.googleauthorYoung Hoon Youn-
dc.identifier.doi22006373-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02988-
dc.contributor.localIdA01063-
dc.contributor.localIdA03902-
dc.contributor.localIdA01108-
dc.contributor.localIdA04382-
dc.contributor.localIdA01210-
dc.contributor.localIdA01281-
dc.contributor.localIdA01426-
dc.contributor.localIdA02035-
dc.contributor.localIdA02583-
dc.contributor.localIdA02812-
dc.relation.journalcodeJ00179-
dc.identifier.eissn1534-4681-
dc.identifier.pmid22006373-
dc.identifier.urlhttp://link.springer.com/article/10.1245%2Fs10434-011-2083-7-
dc.subject.keywordEndoscopic Submucosal Dissection-
dc.subject.keywordEarly Gastric Cancer-
dc.subject.keywordEndoscopic Treatment-
dc.subject.keywordLymphovascular Invasion-
dc.subject.keywordSignet Ring Cell Carcinoma-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.alternativeNameKim, Choong Bai-
dc.contributor.alternativeNameCho, Jae Hee-
dc.contributor.alternativeNameKim, Hyun Ki-
dc.contributor.alternativeNameHyung, Woo Jin-
dc.contributor.alternativeNameKim, Hee Man-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNamePak, Kyung Ho-
dc.contributor.alternativeNameSong, Si Young-
dc.contributor.alternativeNameYoun, Young Hoon-
dc.contributor.alternativeNameLee, Sang Kil-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.contributor.affiliatedAuthorKim, Choong Bai-
dc.contributor.affiliatedAuthorCho, Jae Hee-
dc.contributor.affiliatedAuthorKim, Hyun Ki-
dc.contributor.affiliatedAuthorHyung, Woo Jin-
dc.contributor.affiliatedAuthorKim, Hee Man-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorPak, Kyung Ho-
dc.contributor.affiliatedAuthorSong, Si Young-
dc.contributor.affiliatedAuthorYoun, Young Hoon-
dc.contributor.affiliatedAuthorLee, Sang Kil-
dc.citation.volume19-
dc.citation.number4-
dc.citation.startPage1251-
dc.citation.endPage1256-
dc.identifier.bibliographicCitationANNALS OF SURGICAL ONCOLOGY, Vol.19(4) : 1251-1256, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.