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External validation of nomogram for the prediction of recurrence after curative resection in early gastric cancer
DC Field | Value | Language |
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dc.contributor.author | 김기열 | - |
dc.contributor.author | 김주훈 | - |
dc.contributor.author | 김효송 | - |
dc.contributor.author | 남정모 | - |
dc.contributor.author | 라선영 | - |
dc.date.accessioned | 2014-12-19T16:26:20Z | - |
dc.date.available | 2014-12-19T16:26:20Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0923-7534 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89527 | - |
dc.description.abstract | BACKGROUND: Nomograms are statistics-based tools that provide the overall probability of a specific outcome. In our previous study, we developed a nomogram that predicts recurrence of early gastric cancer (EGC) after curative resection. We carried out this study to externally validate our EGC nomogram. PATIENTS AND METHODS: The EGC nomogram was established from a retrospective EGC database that included 2923 consecutive patients. This nomogram was independently externally validated for a cohort of 1058 consecutive patients. For the EGC nomogram validation, we assessed both discrimination and calibration. RESULTS: Within the follow-up period (median 37 months), a total of 11 patients (1.1%) experienced recurrence. The concordance index (c-index) was 0.7 (P = 0.02) and the result of the overall C index was 0.82 [P = 0.006, 95% confidence interval (CI) 0.59-1.00]. The goodness of fit test showed that the EGC nomogram had significantly good fit for 1- and 2-year survival intervals (P = 0.998 and 0.879, respectively). The actual and predicted survival outcomes showed good agreement, suggesting that the survival predictions from the nomogram are well calibrated externally. CONCLUSIONS: A preexisting nomogram for predicting disease-free survival (DFS) of EGC after surgery was externally validated. The nomogram is useful for accurate and individual prediction of DFS, patient prognostication, counseling, and follow-up planning. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | ANNALS OF ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/pathology | - |
dc.subject.MESH | Adenocarcinoma/surgery* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local* | - |
dc.subject.MESH | Nomograms* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Stomach Neoplasms/pathology | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.title | External validation of nomogram for the prediction of recurrence after curative resection in early gastric cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | J. H. Kim | - |
dc.contributor.googleauthor | H. S. Kim | - |
dc.contributor.googleauthor | W. Y. Seo | - |
dc.contributor.googleauthor | C. M. Nam | - |
dc.contributor.googleauthor | K. Y. Kim | - |
dc.contributor.googleauthor | H. C. Jeung | - |
dc.contributor.googleauthor | J. F. Lai | - |
dc.contributor.googleauthor | H. C. Chung | - |
dc.contributor.googleauthor | S. H. Noh | - |
dc.contributor.googleauthor | S. Y. Rha | - |
dc.identifier.doi | 21566150 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00337 | - |
dc.contributor.localId | A00949 | - |
dc.contributor.localId | A01202 | - |
dc.contributor.localId | A01264 | - |
dc.contributor.localId | A01316 | - |
dc.relation.journalcode | J00171 | - |
dc.identifier.eissn | 1569-8041 | - |
dc.identifier.pmid | 21566150 | - |
dc.subject.keyword | early gastric cancer | - |
dc.subject.keyword | external validation | - |
dc.subject.keyword | nomogram | - |
dc.contributor.alternativeName | Kim, Ki Yeol | - |
dc.contributor.alternativeName | Kim, Joo Hoon | - |
dc.contributor.alternativeName | Kim, Hyo Song | - |
dc.contributor.alternativeName | Nam, Jung Mo | - |
dc.contributor.alternativeName | Rha, Sun Young | - |
dc.contributor.affiliatedAuthor | Kim, Ki Yeol | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Hyo Song | - |
dc.contributor.affiliatedAuthor | Nam, Jung Mo | - |
dc.contributor.affiliatedAuthor | Rha, Sun Young | - |
dc.citation.volume | 23 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 361 | - |
dc.citation.endPage | 367 | - |
dc.identifier.bibliographicCitation | ANNALS OF ONCOLOGY, Vol.23(2) : 361-367, 2012 | - |
dc.identifier.rimsid | 31473 | - |
dc.type.rims | ART | - |
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