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Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in the lateral decubitus position
DC Field | Value | Language |
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dc.contributor.author | 김신형 | - |
dc.contributor.author | 오영준 | - |
dc.contributor.author | 이진구 | - |
dc.contributor.author | 최용선 | - |
dc.date.accessioned | 2014-12-19T16:24:29Z | - |
dc.date.available | 2014-12-19T16:24:29Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0310-057X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89468 | - |
dc.description.abstract | Prolonged inspiratory to expiratory (I:E) ratio ventilation may have both positive and negative effects on respiratory mechanics and oxygenation during one-lung ventilation (OLV), but definitive information is currently lacking. We therefore compared the effects of volume-controlled ventilation with I:E ratios of 1:1 and 1:2 on respiratory mechanics and oxygenation during OLV. Fifty-six patients undergoing thoracoscopic lobectomy were randomly assigned volume-controlled ventilation with an I:E ratio of 1:1 (group 1:1, n=28) or 1:2 (group 1:2, n=28) during OLV. Arterial and central venous blood gas analyses and respiratory variables were recorded 15 minutes into two-lung ventilation, at 30 and 60 minutes during OLV, and 15 minutes after two-lung ventilation was re-initiated. Peak and plateau airway pressures in cmH2O [standard deviation] during OLV were significantly lower in group 1:1 than in group 1:2 (P <0.01) (19 [3] and 23 [4]; 16 [3] and 19 [5], respectively). The arterial to end-tidal carbon dioxide tension difference was significantly lower in group 1:1 than in group 1:2 (P <0.01), (0.5 [0.3] and 1.1 [0.5]). There were no significant differences in PaO2 during OLV between the two groups (OLV30, P=0.856; OLV60, P=0.473). In summary, volume-controlled ventilation with an I:E ratio of 1:1 reduced peak and plateau airway pressures improved dynamic compliance and efficiency of alveolar ventilation, but it did not improve arterial oxygenation in a substantial manner. Furthermore, the associated increase in mean airway pressure might have reduced cardiac output, resulting in a lower central venous oxygen saturation. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | ANAESTHESIA AND INTENSIVE CARE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Blood Gas Analysis | - |
dc.subject.MESH | Carbon Dioxide/metabolism | - |
dc.subject.MESH | Cardiac Output | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Oxygen Consumption* | - |
dc.subject.MESH | Posture* | - |
dc.subject.MESH | Respiration, Artificial/methods* | - |
dc.subject.MESH | Respiratory Mechanics/physiology* | - |
dc.subject.MESH | Thoracoscopy/methods | - |
dc.subject.MESH | Time Factors | - |
dc.title | Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in the lateral decubitus position | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | SH Kim | - |
dc.contributor.googleauthor | YS Choi | - |
dc.contributor.googleauthor | JG Lee | - |
dc.contributor.googleauthor | IH Park | - |
dc.contributor.googleauthor | YJ Oh | - |
dc.identifier.doi | 23194211 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00676 | - |
dc.contributor.localId | A02389 | - |
dc.contributor.localId | A03225 | - |
dc.contributor.localId | A04119 | - |
dc.relation.journalcode | J00129 | - |
dc.identifier.eissn | 1448-0271 | - |
dc.identifier.pmid | 23194211 | - |
dc.identifier.url | http://www.aaic.net.au/Document/?D=20120194 | - |
dc.subject.keyword | one-lung ventilation: inspiratory-expiratory ratio | - |
dc.subject.keyword | oxygenation | - |
dc.subject.keyword | respiratory mechanics | - |
dc.contributor.alternativeName | Kim, Shin Hyung | - |
dc.contributor.alternativeName | Oh, Young Jun | - |
dc.contributor.alternativeName | Lee, Jin Gu | - |
dc.contributor.alternativeName | Choi, Yong Seon | - |
dc.contributor.affiliatedAuthor | Kim, Shin Hyung | - |
dc.contributor.affiliatedAuthor | Oh, Young Jun | - |
dc.contributor.affiliatedAuthor | Lee, Jin Gu | - |
dc.contributor.affiliatedAuthor | Choi, Yong Seon | - |
dc.citation.volume | 40 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1016 | - |
dc.citation.endPage | 1022 | - |
dc.identifier.bibliographicCitation | ANAESTHESIA AND INTENSIVE CARE, Vol.40(6) : 1016-1022, 2012 | - |
dc.identifier.rimsid | 31791 | - |
dc.type.rims | ART | - |
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