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Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in the lateral decubitus position

DC FieldValueLanguage
dc.contributor.author김신형-
dc.contributor.author오영준-
dc.contributor.author이진구-
dc.contributor.author최용선-
dc.date.accessioned2014-12-19T16:24:29Z-
dc.date.available2014-12-19T16:24:29Z-
dc.date.issued2012-
dc.identifier.issn0310-057X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89468-
dc.description.abstractProlonged inspiratory to expiratory (I:E) ratio ventilation may have both positive and negative effects on respiratory mechanics and oxygenation during one-lung ventilation (OLV), but definitive information is currently lacking. We therefore compared the effects of volume-controlled ventilation with I:E ratios of 1:1 and 1:2 on respiratory mechanics and oxygenation during OLV. Fifty-six patients undergoing thoracoscopic lobectomy were randomly assigned volume-controlled ventilation with an I:E ratio of 1:1 (group 1:1, n=28) or 1:2 (group 1:2, n=28) during OLV. Arterial and central venous blood gas analyses and respiratory variables were recorded 15 minutes into two-lung ventilation, at 30 and 60 minutes during OLV, and 15 minutes after two-lung ventilation was re-initiated. Peak and plateau airway pressures in cmH2O [standard deviation] during OLV were significantly lower in group 1:1 than in group 1:2 (P <0.01) (19 [3] and 23 [4]; 16 [3] and 19 [5], respectively). The arterial to end-tidal carbon dioxide tension difference was significantly lower in group 1:1 than in group 1:2 (P <0.01), (0.5 [0.3] and 1.1 [0.5]). There were no significant differences in PaO2 during OLV between the two groups (OLV30, P=0.856; OLV60, P=0.473). In summary, volume-controlled ventilation with an I:E ratio of 1:1 reduced peak and plateau airway pressures improved dynamic compliance and efficiency of alveolar ventilation, but it did not improve arterial oxygenation in a substantial manner. Furthermore, the associated increase in mean airway pressure might have reduced cardiac output, resulting in a lower central venous oxygen saturation.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfANAESTHESIA AND INTENSIVE CARE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBlood Gas Analysis-
dc.subject.MESHCarbon Dioxide/metabolism-
dc.subject.MESHCardiac Output-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOxygen Consumption*-
dc.subject.MESHPosture*-
dc.subject.MESHRespiration, Artificial/methods*-
dc.subject.MESHRespiratory Mechanics/physiology*-
dc.subject.MESHThoracoscopy/methods-
dc.subject.MESHTime Factors-
dc.titleEffects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in the lateral decubitus position-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorSH Kim-
dc.contributor.googleauthorYS Choi-
dc.contributor.googleauthorJG Lee-
dc.contributor.googleauthorIH Park-
dc.contributor.googleauthorYJ Oh-
dc.identifier.doi23194211-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00676-
dc.contributor.localIdA02389-
dc.contributor.localIdA03225-
dc.contributor.localIdA04119-
dc.relation.journalcodeJ00129-
dc.identifier.eissn1448-0271-
dc.identifier.pmid23194211-
dc.identifier.urlhttp://www.aaic.net.au/Document/?D=20120194-
dc.subject.keywordone-lung ventilation: inspiratory-expiratory ratio-
dc.subject.keywordoxygenation-
dc.subject.keywordrespiratory mechanics-
dc.contributor.alternativeNameKim, Shin Hyung-
dc.contributor.alternativeNameOh, Young Jun-
dc.contributor.alternativeNameLee, Jin Gu-
dc.contributor.alternativeNameChoi, Yong Seon-
dc.contributor.affiliatedAuthorKim, Shin Hyung-
dc.contributor.affiliatedAuthorOh, Young Jun-
dc.contributor.affiliatedAuthorLee, Jin Gu-
dc.contributor.affiliatedAuthorChoi, Yong Seon-
dc.citation.volume40-
dc.citation.number6-
dc.citation.startPage1016-
dc.citation.endPage1022-
dc.identifier.bibliographicCitationANAESTHESIA AND INTENSIVE CARE, Vol.40(6) : 1016-1022, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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