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Efficacy of drug-eluting stents for treating in-stent restenosis of drug-eluting stents (from the Korean DES ISR multicenter registry study [KISS]).

DC FieldValueLanguage
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author장양수-
dc.date.accessioned2014-12-19T16:22:32Z-
dc.date.available2014-12-19T16:22:32Z-
dc.date.issued2012-
dc.identifier.issn0002-9149-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89408-
dc.description.abstractThere is currently no established standard treatment for in-stent restenosis (ISR) after the implantation of a drug-eluting stent (DES). The aim of this study was to investigate the efficacy of DES versus balloon angioplasty (BA) for the treatment of DES ISR in a multicenter registry cohort. After matching propensity scores of 805 patients with DES ISR treated with either DES (n = 422) or BA (n = 383), 268 matched pairs were selected and analyzed for major adverse cardiac events, a composite of death, myocardial infarction, and target-vessel revascularization, as the primary end point. Baseline clinical and lesion characteristics of the matched pairs were similar. Survival free of major adverse cardiac events at 2 years was higher with DES compared to BA (88.9% vs 78.7%, p <0.001), mainly because of higher TVR-free survival (92.4% vs 81.0%, p <0.001). Among various baseline variables, BA (hazard ratio 2.546, 95% confidence interval 1.412 to 4.593, p = 0.002) was the most important independent risk factor for recurrent target vessel revascularization, followed by acute coronary syndromes as the clinical presentation of DES ISR, and previous implantation of a sirolimus-eluting stent. Survival free of death, myocardial infarction, or stent thrombosis did not differ between the 2 groups. Whereas there was no significant difference in survival free of target vessel revascularization between DES and BA for focal ISR lesions, DES was superior to BA in diffuse ISR lesions (94.3% vs 75.2% at 2 years, p <0.001). In conclusion, compared to BA, the implantation of DES was safe and more effective in the treatment of DES ISR.-
dc.description.statementOfResponsibilityopen-
dc.format.extent607~613-
dc.relation.isPartOfAMERICAN JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAngioplasty, Balloon, Coronary/methods*-
dc.subject.MESHCause of Death/trends-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Restenosis/diagnostic imaging-
dc.subject.MESHCoronary Restenosis/epidemiology-
dc.subject.MESHCoronary Restenosis/surgery*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHElectrocardiography*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction/diagnosis-
dc.subject.MESHMyocardial Infarction/epidemiology*-
dc.subject.MESHMyocardial Infarction/etiology-
dc.subject.MESHPrognosis-
dc.subject.MESHPropensity Score-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRegistries*-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHTreatment Failure-
dc.subject.MESHTreatment Outcome-
dc.titleEfficacy of drug-eluting stents for treating in-stent restenosis of drug-eluting stents (from the Korean DES ISR multicenter registry study [KISS]).-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorDong Woon Jeon-
dc.contributor.googleauthorJoo-Young Yang-
dc.contributor.googleauthorYoung Keun Ahn-
dc.contributor.googleauthorMyung Ho Jeong-
dc.contributor.googleauthorCheol Woong Yu-
dc.contributor.googleauthorKyeong-Ho Yun-
dc.contributor.googleauthorDo-Sun Lim-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi22172241-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA03448-
dc.relation.journalcodeJ00071-
dc.identifier.eissn1879-1913 -
dc.identifier.pmid22172241-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0002914911031882-
dc.subject.keywordAngioplasty, Balloon, Coronary/methods*-
dc.subject.keywordCause of Death/trends-
dc.subject.keywordCoronary Angiography-
dc.subject.keywordCoronary Restenosis/diagnostic imaging-
dc.subject.keywordCoronary Restenosis/epidemiology-
dc.subject.keywordCoronary Restenosis/surgery*-
dc.subject.keywordDrug-Eluting Stents*-
dc.subject.keywordElectrocardiography*-
dc.subject.keywordFemale-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordIncidence-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordMyocardial Infarction/diagnosis-
dc.subject.keywordMyocardial Infarction/epidemiology*-
dc.subject.keywordMyocardial Infarction/etiology-
dc.subject.keywordPrognosis-
dc.subject.keywordPropensity Score-
dc.subject.keywordProportional Hazards Models-
dc.subject.keywordRegistries*-
dc.subject.keywordRepublic of Korea/epidemiology-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordRisk Factors-
dc.subject.keywordSurvival Rate/trends-
dc.subject.keywordTreatment Failure-
dc.subject.keywordTreatment Outcome-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.citation.volume109-
dc.citation.number5-
dc.citation.startPage607-
dc.citation.endPage613-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF CARDIOLOGY, Vol.109(5) : 607-613, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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