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ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT).

DC FieldValueLanguage
dc.contributor.author홍명기-
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author신동호-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.date.accessioned2014-12-19T16:22:28Z-
dc.date.available2014-12-19T16:22:28Z-
dc.date.issued2012-
dc.identifier.issn0002-8703-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89406-
dc.description.abstractBACKGROUND: Data on strut surface coverage of second-generation drug-eluting stents (DES) are limited. We investigated stent strut coverage of resolute zotarolimus-eluting stent (ZES-R) or everolimus-eluting stent (EES) at 9 months after implantation using optical coherence tomography (OCT). METHODS: ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT) is a prospective, randomized, multicenter trial comparing ZES-R to EES using OCT at 9 months after stent implantation. The primary end point was the rate of stent strut coverage at 9 months. RESULTS: A total of 51 patients were randomized to receive either ZES-R (ZES-R group) or EES (EES group), and 47 stents (24 ZES-R and 23 EES) in 44 of 51 patients were evaluated by OCT both immediately after stent implantation and at 9 months. The neointimal thickness was not significantly different between the 2 groups at 9 months (ZES-R vs EES: 139 ± 58 vs 124 ± 42 μm, P = .31). The mean percentages of uncovered stent struts were 3.3% for ZES-R versus 3.4% for EES at 9 months (P = .51). The proportions of malapposed struts immediately after stent implantation (P = .89) and at 9-month follow-up (P = .34) were 0.8% and 0.7% for ZES-R versus 1.0% and 0.1% for EES, respectively. Thrombi were documented in 1 stent (1 [4.2%] in ZES-R vs 0 [0%] in EES). CONCLUSION: According to the sequential OCT evaluation, ZES-R and EES showed comparable neointimal thickness and the rate of uncovered stent strut at 9 months after stent implantation.-
dc.description.statementOfResponsibilityopen-
dc.format.extent601~607-
dc.relation.isPartOfAMERICAN HEART JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHEverolimus-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImage Processing, Computer-Assisted-
dc.subject.MESHImmunosuppressive Agents/administration & dosage*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHProspective Studies-
dc.subject.MESHSirolimus/administration & dosage-
dc.subject.MESHSirolimus/analogs & derivatives*-
dc.subject.MESHTomography, Optical Coherence*-
dc.titleComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT).-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Kuk Kim-
dc.contributor.googleauthorIk-Kyung Jang-
dc.contributor.googleauthorDong-Ho Shin-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorYun-Kyeong Cho-
dc.contributor.googleauthorChang-Wook Nam-
dc.contributor.googleauthorSeung-Ho Hur-
dc.contributor.googleauthorJin-Ho Choi-
dc.contributor.googleauthorYoung Bin Song-
dc.contributor.googleauthorJoo Yong Hahn-
dc.contributor.googleauthorSeung Hyuk Choi-
dc.contributor.googleauthorHyeon Cheol Gwon-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi22520526-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04391-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02097-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.relation.journalcodeJ00069-
dc.identifier.eissn1097-6744-
dc.identifier.pmid22520526-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0002870311007769-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordCoronary Angiography-
dc.subject.keywordDrug-Eluting Stents*-
dc.subject.keywordEverolimus-
dc.subject.keywordFemale-
dc.subject.keywordHumans-
dc.subject.keywordImage Processing, Computer-Assisted-
dc.subject.keywordImmunosuppressive Agents/administration & dosage*-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordProspective Studies-
dc.subject.keywordSirolimus/administration & dosage-
dc.subject.keywordSirolimus/analogs & derivatives*-
dc.subject.keywordTomography, Optical Coherence*-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameShin, Dong Ho-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorShin, Dong Ho-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.citation.volume163-
dc.citation.number4-
dc.citation.startPage601-
dc.citation.endPage607-
dc.identifier.bibliographicCitationAMERICAN HEART JOURNAL, Vol.163(4) : 601-607, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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