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Prognostic Value of Model for End-Stage Liver Disease Scores in Patients with Fulminant Hepatic Failure

DC FieldValueLanguage
dc.contributor.author김도영-
dc.contributor.author김명수-
dc.contributor.author김순일-
dc.contributor.author박정엽-
dc.contributor.author안상훈-
dc.contributor.author이형순-
dc.contributor.author주동진-
dc.contributor.author최기홍-
dc.contributor.author최진섭-
dc.contributor.author한광협-
dc.date.accessioned2014-12-18T10:00:56Z-
dc.date.available2014-12-18T10:00:56Z-
dc.date.issued2013-
dc.identifier.issn0041-1345-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89255-
dc.description.abstractBACKGROUND: This study was undertaken to investigate risk factors of mortality in patients with fulminant hepatic failure (FHF). METHODS: Fifty-three patients with FHF treated from January 2006 to April 2011 were allocated to a spontaneous survival group (group 1), a death without liver transplantation (LT) group (group 2), and an LT group (group 3). To analyze risk factors associated with mortality in FHF, we excluded group 3 patients. Clinical features, Model for End-Stage Liver Disease (MELD) scores, and King's College Hospital criteria at the time of hepatic encephalopathy in group 2 were compared with those of group 1. RESULTS: The causes of FHF were acute viral infection (n = 29, hepatitis A:B, 28:1), drugs (n = 18; including 4 acetaminophen and 14 herbal medication), autoimmune (n = 4), and miscellaneous (n = 2). Of the 53 patients, 19 were allocated to group 1, 18 to group 2, and 16 to group 3. According to univariate analysis, risk factors for mortality in group 2 were acute renal failure requiring renal replacement therapy and a MELD score ≥30 at the time of hepatic encephalopathy. However, by multivariate analysis, a MELD score ≥30 was the only independent risk factor for mortality in group 2 (P = .042; hazard ratio, 4.500). CONCLUSIONS: A MELD score ≥30 was found to be the only independent risk factor of mortality in FHF patients without LT. Therefore, the findings of this study suggest that these patients may need emergent LT for survival.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfTRANSPLANTATION PROCEEDINGS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLiver Failure, Acute/etiology-
dc.subject.MESHLiver Failure, Acute/physiopathology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrognosis-
dc.subject.MESHRisk Factors-
dc.subject.MESHYoung Adult-
dc.titlePrognostic Value of Model for End-Stage Liver Disease Scores in Patients with Fulminant Hepatic Failure-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorH.S. Lee-
dc.contributor.googleauthorG.H. Choi-
dc.contributor.googleauthorD.J. Joo-
dc.contributor.googleauthorM.S. Kim-
dc.contributor.googleauthorS.I. Kim-
dc.contributor.googleauthorK.H. Han-
dc.contributor.googleauthorS.H. Ahn-
dc.contributor.googleauthorD.Y. Kim-
dc.contributor.googleauthorJ.Y. Park-
dc.contributor.googleauthorJ.S. Choi-
dc.identifier.doi10.1016/j.transproceed.2013.08.036-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00649-
dc.contributor.localIdA01647-
dc.contributor.localIdA02226-
dc.contributor.localIdA03304-
dc.contributor.localIdA03948-
dc.contributor.localIdA04046-
dc.contributor.localIdA04199-
dc.contributor.localIdA04268-
dc.contributor.localIdA00385-
dc.contributor.localIdA00424-
dc.relation.journalcodeJ02755-
dc.identifier.eissn1873-2623-
dc.identifier.pmid24157020-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0041134513007793-
dc.subject.keywordAdolescent-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordAged, 80 and over-
dc.subject.keywordFemale-
dc.subject.keywordHumans-
dc.subject.keywordLiver Failure, Acute/etiology-
dc.subject.keywordLiver Failure, Acute/physiopathology*-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPrognosis-
dc.subject.keywordRisk Factors-
dc.subject.keywordYoung Adult-
dc.contributor.alternativeNameKim, Do Young-
dc.contributor.alternativeNameKim, Myoung Soo-
dc.contributor.alternativeNameKim, Soon Il-
dc.contributor.alternativeNamePark, Jeong Youp-
dc.contributor.alternativeNameAhn, Sang Hoon-
dc.contributor.alternativeNameLee, Hyung Soon-
dc.contributor.alternativeNameJoo, Dong Jin-
dc.contributor.alternativeNameChoi, Gi Hong-
dc.contributor.alternativeNameChoi, Jin Sub-
dc.contributor.alternativeNameHan, Kwang Hyup-
dc.contributor.affiliatedAuthorKim, Soon Il-
dc.contributor.affiliatedAuthorPark, Jeong Youp-
dc.contributor.affiliatedAuthorAhn, Sang Hoon-
dc.contributor.affiliatedAuthorLee, Hyung Soon-
dc.contributor.affiliatedAuthorJoo, Dong Jin-
dc.contributor.affiliatedAuthorChoi, Gi Hong-
dc.contributor.affiliatedAuthorChoi, Jin Sub-
dc.contributor.affiliatedAuthorHan, Kwang Hyup-
dc.contributor.affiliatedAuthorKim, Do Young-
dc.contributor.affiliatedAuthorKim, Myoung Soo-
dc.rights.accessRightsnot free-
dc.citation.volume45-
dc.citation.number8-
dc.citation.startPage2992-
dc.citation.endPage2994-
dc.identifier.bibliographicCitationTRANSPLANTATION PROCEEDINGS, Vol.45(8) : 2992-2994, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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