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Anticancer Effect of Phellinus linteus; Potential Clinical Application in Treating Pancreatic Ductal Adenocarcinoma

DC Field Value Language
dc.contributor.author강창무-
dc.contributor.author이우정-
dc.contributor.author최성훈-
dc.contributor.author한대훈-
dc.contributor.author황호경-
dc.date.accessioned2014-12-18T09:58:46Z-
dc.date.available2014-12-18T09:58:46Z-
dc.date.issued2013-
dc.identifier.issn2157-2518-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89190-
dc.description.abstractPancreatic cancer (ductal adenocarcinoma) is one of the most lethal malignancies in gastrointestinal system. Till now, only margin-negative pancreatectomy is known to be the best treatment option for long-term survival. However, the resection rate is reported to be less than 20%. Even in cases of curative resection, most patients generally experience disease recurrence and ultimately die of metastatic disease. Therefore, surgery alone is not enough and adjuvant systemic chemotherapy should be considered for proper management of pancreatic cancer. But, its related toxicity and insufficient oncologic effect requires development of less toxic and more effective alternative treatments for pancreatic cancer. Phellinus linteus (PL), a basidiomycete, is a species of mushroom, which is reported to have the most potent antitumor effect of the basidiomycetes. Recently, there are accumulating researches discovering biologic mechanisms of PL in antitumor effect. However, very few studies were done in pancreatic cancer treatment. In this review, literatures demonstrating the anticancer effects of PL were summarized and some encouraging research data suggesting mushroom component can be alternative approach even in treating pancreatic cancer were reviewed, including our preliminary data suggesting the potential clinical application of PL in treating pancreatic cancer.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJournal of Carcinogenesis & Mutagenesis-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAnticancer Effect of Phellinus linteus; Potential Clinical Application in Treating Pancreatic Ductal Adenocarcinoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorChang Moo Kang-
dc.contributor.googleauthorDai Hoon Han-
dc.contributor.googleauthorHo Kyoung Hwnag-
dc.contributor.googleauthorSung Hoon Choi-
dc.contributor.googleauthorWoo Jung Lee-
dc.identifier.doi10.4172/2157-2518.S9-001-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04085-
dc.contributor.localIdA02993-
dc.contributor.localIdA00088-
dc.contributor.localIdA04273-
dc.contributor.localIdA04497-
dc.relation.journalcodeJ01284-
dc.identifier.pmidPancreatic cancer ; Phellinus linteus ; Basidiomycete ; Adjuvant chemotherapy-
dc.subject.keywordPancreatic cancer-
dc.subject.keywordPhellinus linteus-
dc.subject.keywordBasidiomycete-
dc.subject.keywordAdjuvant chemotherapy-
dc.contributor.alternativeNameKang, Chang Moo-
dc.contributor.alternativeNameLee, Woo Jung-
dc.contributor.alternativeNameChoi, Sung Hoon-
dc.contributor.alternativeNameHan, Dai Hoon-
dc.contributor.alternativeNameHwang, Ho Kyoung-
dc.contributor.affiliatedAuthorChoi, Sung Hoon-
dc.contributor.affiliatedAuthorLee, Woo Jung-
dc.contributor.affiliatedAuthorKang, Chang Moo-
dc.contributor.affiliatedAuthorHan, Dai Hoon-
dc.contributor.affiliatedAuthorHwang, Ho Kyoung-
dc.rights.accessRightsfree-
dc.citation.volumeS9-
dc.citation.number001-
dc.citation.startPage1-
dc.citation.endPage8-
dc.identifier.bibliographicCitationJournal of Carcinogenesis & Mutagenesis, Vol.S9(001) : 1-8, 2013-
dc.identifier.rimsid34436-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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