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QTc Prolongation after Ventricular Septal Defect Repair in Infants

DC Field Value Language
dc.contributor.author신홍주-
dc.contributor.author우샛별-
dc.contributor.author정조원-
dc.contributor.author최재영-
dc.contributor.author김남균-
dc.contributor.author박영환-
dc.contributor.author박한기-
dc.date.accessioned2014-12-18T09:56:24Z-
dc.date.available2014-12-18T09:56:24Z-
dc.date.issued2013-
dc.identifier.issn1738-5520-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89115-
dc.description.abstractBACKGROUND AND OBJECTIVES: Prolonging of the corrected QT interval (QTc) has been reported after cardiac surgery in some studies. However, there have not been many studies on infant open cardiac surgery for ventricular septal defect (VSD) repair. This study was performed to define the changes in QTc and to find related post-surgery factors in this patient group. SUBJECTS AND METHODS: From 2008 to 2012, 154 infants underwent VSD repair at the Severance Cardiovascular Hospital. This study includes 105 of these cases. QTc was measured in these patients retrospectively. Demographic data and peri-procedural data, such as Aristotle score, cross-clamp time and bypass time, were analyzed. The exclusion criteria included multiple and small VSDs that underwent direct closure. RESULTS: Mean post-operative QTc was increased compared to the pre-operative measurements (from 413.6±2.3 to 444.9±2.5, p<0.001). In multiple linear regression, the comprehensive Aristotle score was associated with increasing QTc (p=0.047). The incidence of transient arrhythmia, such as atrial tachycardia, junctional ectopic tachycardia, premature atrial contraction, or premature ventricular contraction, was associated with QTc prolongation (p=0.005). Prolonged QTc was also associated with cross-clamp time (p=0.008) and low weight (p=0.042). Total length of stay at the intensive care unit and intubation time after surgery were not associated with QTc prolongation. CONCLUSION: Prolonged QTc could be seen after VSD repair in infants. This phenomenon was associated with peri-procedural factors such as the Aristotle score and cross-clamp time. Patients with QTc prolongation after cardiac surgery had an increased tendency towards arrhythmogenicity in the post-operative period.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfKOREAN CIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleQTc Prolongation after Ventricular Septal Defect Repair in Infants-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery (흉부외과학)-
dc.contributor.googleauthorChang Woo Han-
dc.contributor.googleauthorSaet Byul Woo-
dc.contributor.googleauthorJae Young Choi-
dc.contributor.googleauthorJo Won Jung-
dc.contributor.googleauthorYong Hwan Park-
dc.contributor.googleauthorHan Ki Park-
dc.contributor.googleauthorHong Ju Shin-
dc.contributor.googleauthorNam Kyun Kim-
dc.identifier.doi10.4070/kcj.2013.43.12.825-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04174-
dc.contributor.localIdA02185-
dc.contributor.localIdA02425-
dc.contributor.localIdA03720-
dc.contributor.localIdA00355-
dc.contributor.localIdA01574-
dc.contributor.localIdA01729-
dc.relation.journalcodeJ01952-
dc.identifier.eissn1738-5555-
dc.identifier.pmid24385994-
dc.subject.keywordElectrocardiography-
dc.subject.keywordInfant-
dc.subject.keywordVentricular septal defect-
dc.contributor.alternativeNameShin, Hong Ju-
dc.contributor.alternativeNameWoo, Saet Byul-
dc.contributor.alternativeNameJung, Jo Won-
dc.contributor.alternativeNameChoi, Jae Young-
dc.contributor.alternativeNameKim, Nam Kyun-
dc.contributor.alternativeNamePark, Young Hwan-
dc.contributor.alternativeNamePark, Han Ki-
dc.contributor.affiliatedAuthorChoi, Jae Young-
dc.contributor.affiliatedAuthorShin, Hong Ju-
dc.contributor.affiliatedAuthorWoo, Saet Byul-
dc.contributor.affiliatedAuthorJung, Jo Won-
dc.contributor.affiliatedAuthorKim, Nam Kyun-
dc.contributor.affiliatedAuthorPark, Young Hwan-
dc.contributor.affiliatedAuthorPark, Han Ki-
dc.rights.accessRightsfree-
dc.citation.volume43-
dc.citation.number12-
dc.citation.startPage825-
dc.citation.endPage829-
dc.identifier.bibliographicCitationKOREAN CIRCULATION JOURNAL, Vol.43(12) : 825-829, 2013-
dc.identifier.rimsid33811-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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