Cited 7 times in
Role of radiotherapy for pancreatobiliary neuroendocrine tumors
DC Field | Value | Language |
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dc.contributor.author | 최치환 | - |
dc.contributor.author | 성진실 | - |
dc.date.accessioned | 2014-12-18T09:52:44Z | - |
dc.date.available | 2014-12-18T09:52:44Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2234-1900 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88999 | - |
dc.description.abstract | PURPOSE: We investigated the role of radiotherapy (RT) for pancreatobiliary neuroendocrine tumors (PB-NETs). MATERIALS AND METHODS: We identified 9 patients with PB-NETs who received RT between January 2005 and March 2012. Of these 9 patients, 4 were diagnosed with NETs in the pancreas and 5 were diagnosed with NETs in the gallbladder. All patients received RT to the primary tumor or resection bed with a median total irradiation dose of 50.4 Gy, with or without chemotherapy. RESULTS: The tumor response rate and tumor control rate in the RT field were 60% and 100 %, respectively. All 4 patients who underwent surgery had no evidence of disease in the RT field. Of the 5 patients who received RT to the primary gross tumor, 1 had complete response, 2 had partial response, and 2 had stable disease in the RT field. The median time to progression was 11 months. Of the 9 patients, four patients had no progression, and 5 patients had progression of disease (locoregional, 2; distant, 2; locoregional/distant, 1). Of the 4 patients without progression, 3 were treated with RT in adjuvant or neoadjuvant setting, and one received RT to primary tumor. One patient experienced radiation-induced duodenitis at 3 months after concurrent chemoradiation without treatment-related mortality. CONCLUSION: RT can yield local control for advanced PB-NETs. RT should be considered an essential part of multimodality treatment in management of advanced PB-NETs. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | RADIATION ONCOLOGY JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Role of radiotherapy for pancreatobiliary neuroendocrine tumors | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학) | - |
dc.contributor.googleauthor | Jeongshim Lee | - |
dc.contributor.googleauthor | Jinhyun Choi | - |
dc.contributor.googleauthor | Chihwan Choi | - |
dc.contributor.googleauthor | Jinsil Seong | - |
dc.identifier.doi | 10.3857/roj.2013.31.3.125 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04203 | - |
dc.contributor.localId | A01956 | - |
dc.relation.journalcode | J02592 | - |
dc.identifier.eissn | 2234-3164 | - |
dc.identifier.pmid | 24137557 | - |
dc.subject.keyword | Neuroendocrine tumors | - |
dc.subject.keyword | Radiotherapy | - |
dc.subject.keyword | Treatment outcome | - |
dc.contributor.alternativeName | Choi, Chi Hwan | - |
dc.contributor.alternativeName | Seong, Jin Sil | - |
dc.contributor.affiliatedAuthor | Choi, Chi Hwan | - |
dc.contributor.affiliatedAuthor | Seong, Jin Sil | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 31 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 125 | - |
dc.citation.endPage | 130 | - |
dc.identifier.bibliographicCitation | RADIATION ONCOLOGY JOURNAL, Vol.31(3) : 125-130, 2013 | - |
dc.identifier.rimsid | 33732 | - |
dc.type.rims | ART | - |
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