Cited 5 times in
Prolonged clinical benefit from the maintenance hormone therapy in patients with metastatic breast cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김주항 | - |
dc.contributor.author | 박병우 | - |
dc.contributor.author | 박세호 | - |
dc.contributor.author | 손주혁 | - |
dc.contributor.author | 이수현 | - |
dc.contributor.author | 임승택 | - |
dc.contributor.author | 최혜진 | - |
dc.contributor.author | 한정우 | - |
dc.contributor.author | 김승일 | - |
dc.date.accessioned | 2014-12-18T09:50:22Z | - |
dc.date.available | 2014-12-18T09:50:22Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0960-9776 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88927 | - |
dc.description.abstract | Objective We investigated the efficacy of maintenance hormone therapy (MHT), which was given to hormone positive metastatic breast cancer (MBC) patients in non-progression status to the previous chemotherapy. Methods This study retrospectively analyzed 76 MBC patients who had been treated with MHT from 2006 to 2010 at a single institute. Results For the 76 patients reviewed, the median progression free survival (PFS) to MHT was 14.4 months (95% CI, 11.6–17.3). Prolonged PFS was associated with less previous palliative chemotherapy, fewer metastatic sites, and the absence of visceral metastasis in univariate analysis. Multivariate analysis showed that only the number of previous palliative chemotherapy (HR 1.73, 95% CI, 1.00–2.98; P = 0.04) remained as a significant variable. MHT was generally well tolerated. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | BREAST | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antineoplastic Agents/adverse effects | - |
dc.subject.MESH | Antineoplastic Agents/therapeutic use* | - |
dc.subject.MESH | Aromatase Inhibitors/adverse effects | - |
dc.subject.MESH | Aromatase Inhibitors/therapeutic use* | - |
dc.subject.MESH | Breast Neoplasms/chemistry | - |
dc.subject.MESH | Breast Neoplasms/drug therapy* | - |
dc.subject.MESH | Breast Neoplasms/pathology | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Maintenance Chemotherapy* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Metastasis | - |
dc.subject.MESH | Palliative Care* | - |
dc.subject.MESH | Receptors, Estrogen/analysis | - |
dc.subject.MESH | Receptors, Progesterone/analysis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Selective Estrogen Receptor Modulators/adverse effects | - |
dc.subject.MESH | Selective Estrogen Receptor Modulators/therapeutic use* | - |
dc.title | Prolonged clinical benefit from the maintenance hormone therapy in patients with metastatic breast cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Seungtaek Lim | - |
dc.contributor.googleauthor | Soohyeon Lee | - |
dc.contributor.googleauthor | Jungwoo Han | - |
dc.contributor.googleauthor | Byeong-Woo Park | - |
dc.contributor.googleauthor | SeungIl Kim | - |
dc.contributor.googleauthor | Seho Park | - |
dc.contributor.googleauthor | Joo-Hang Kim | - |
dc.contributor.googleauthor | Hye Jin Choi | - |
dc.contributor.googleauthor | Joohyuk Sohn | - |
dc.identifier.doi | 10.1016/j.breast.2013.08.013 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00945 | - |
dc.contributor.localId | A01475 | - |
dc.contributor.localId | A01524 | - |
dc.contributor.localId | A01995 | - |
dc.contributor.localId | A03380 | - |
dc.contributor.localId | A04219 | - |
dc.contributor.localId | A00658 | - |
dc.contributor.localId | A04325 | - |
dc.contributor.localId | A02898 | - |
dc.relation.journalcode | J00400 | - |
dc.identifier.eissn | 1532-3080 | - |
dc.identifier.pmid | 24135766 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0960977613002476 | - |
dc.subject.keyword | Breast cancer | - |
dc.subject.keyword | ER | - |
dc.subject.keyword | Hormone therapy | - |
dc.subject.keyword | MBC | - |
dc.subject.keyword | MHT | - |
dc.subject.keyword | MPA | - |
dc.subject.keyword | Maintenance | - |
dc.subject.keyword | OS | - |
dc.subject.keyword | PFS | - |
dc.subject.keyword | PR | - |
dc.subject.keyword | RECIST | - |
dc.subject.keyword | estrogen receptor | - |
dc.subject.keyword | maintenance hormone therapy | - |
dc.subject.keyword | medroxyprogesteron acetate | - |
dc.subject.keyword | metastatic breast cancer | - |
dc.subject.keyword | overall survival | - |
dc.subject.keyword | progesterone receptor | - |
dc.subject.keyword | progression free survival | - |
dc.subject.keyword | response evaluation criteria in solid tumors | - |
dc.contributor.alternativeName | Kim, Joo Hang | - |
dc.contributor.alternativeName | Park, Byeong Woo | - |
dc.contributor.alternativeName | Park, Se Ho | - |
dc.contributor.alternativeName | Sohn, Joo Hyuk | - |
dc.contributor.alternativeName | Lee, Soo Hyeon | - |
dc.contributor.alternativeName | Lim, Seung Taek | - |
dc.contributor.alternativeName | Choi, Hye Jin | - |
dc.contributor.alternativeName | Han, Jung Woo | - |
dc.contributor.alternativeName | Kim, Seung Il | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hang | - |
dc.contributor.affiliatedAuthor | Park, Byeong Woo | - |
dc.contributor.affiliatedAuthor | Park, Se Ho | - |
dc.contributor.affiliatedAuthor | Sohn, Joo Hyuk | - |
dc.contributor.affiliatedAuthor | Lim, Seung Taek | - |
dc.contributor.affiliatedAuthor | Choi, Hye Jin | - |
dc.contributor.affiliatedAuthor | Kim, Seung Il | - |
dc.contributor.affiliatedAuthor | Han, Jung Woo | - |
dc.contributor.affiliatedAuthor | Lee, Soo Hyeon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 22 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1205 | - |
dc.citation.endPage | 1209 | - |
dc.identifier.bibliographicCitation | BREAST, Vol.22(6) : 1205-1209, 2013 | - |
dc.identifier.rimsid | 33914 | - |
dc.type.rims | ART | - |
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