Cited 5 times in
Predictive value of the smell identification test for nigrostriatal dopaminergic depletion in Korean tremor patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 홍진용 | - |
dc.contributor.author | 선우문경 | - |
dc.contributor.author | 손영호 | - |
dc.contributor.author | 이지은 | - |
dc.contributor.author | 이필휴 | - |
dc.contributor.author | 정석종 | - |
dc.date.accessioned | 2014-12-18T09:50:08Z | - |
dc.date.available | 2014-12-18T09:50:08Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1353-8020 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88920 | - |
dc.description.abstract | BACKGROUND: The predictive value of Cross-Cultural Smell Identification Test for nigrostriatal dopaminergic depletion in Korean tremor patients has yet to be assessed. METHODS: Three hundred nineteen drug-naive patients who visited our clinic for the diagnosis of their tremor, and took both Cross-Cultural Smell Identification Test and dopamine transporter PET were included in the data analysis. Visual grading of each PET image was performed by two independent neurologists. RESULTS: Smell test scores were significantly correlated to the striatal dopaminergic activity (Kendall's τb = -0.291, p < 0.001). However, smell test score alone appeared to have relatively weak power for predicting dopaminergic depletion (area under the curve = 0.693). Multivariate logistic regression model with inclusion of the patient's age and symptom duration as independent variables enhanced predictive power for dopaminergic depletion (area under the curve = 0.812). CONCLUSIONS: These results demonstrated that Cross-Cultural Smell Identification Test measurements alone may be insufficient to predict striatal dopaminergic depletion in Korean tremor patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | PARKINSONISM & RELATED DISORDERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Corpus Striatum/diagnostic imaging | - |
dc.subject.MESH | Corpus Striatum/metabolism* | - |
dc.subject.MESH | Cross-Cultural Comparison* | - |
dc.subject.MESH | Dopamine/metabolism* | - |
dc.subject.MESH | Dopamine Plasma Membrane Transport Proteins/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Positron-Emission Tomography/methods | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Republic of Korea/ethnology | - |
dc.subject.MESH | Single-Blind Method | - |
dc.subject.MESH | Smell/physiology* | - |
dc.subject.MESH | Substantia Nigra/diagnostic imaging | - |
dc.subject.MESH | Substantia Nigra/metabolism* | - |
dc.subject.MESH | Tremor/diagnosis* | - |
dc.subject.MESH | Tremor/ethnology* | - |
dc.title | Predictive value of the smell identification test for nigrostriatal dopaminergic depletion in Korean tremor patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Jin Yong Hong | - |
dc.contributor.googleauthor | Seok Jong Chung | - |
dc.contributor.googleauthor | Ji E. Lee | - |
dc.contributor.googleauthor | Mun Kyung Sunwoo | - |
dc.contributor.googleauthor | Phil Hyu Lee | - |
dc.contributor.googleauthor | Young H. Sohn | - |
dc.identifier.doi | 10.1016/j.parkreldis.2013.07.008 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04442 | - |
dc.contributor.localId | A01935 | - |
dc.contributor.localId | A01982 | - |
dc.contributor.localId | A03270 | - |
dc.contributor.localId | A03210 | - |
dc.relation.journalcode | J02468 | - |
dc.identifier.eissn | 1873-5126 | - |
dc.identifier.pmid | 23920135 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1353802013002629 | - |
dc.subject.keyword | Cross-Cultural Smell Identification Test | - |
dc.subject.keyword | Dopamine transporter | - |
dc.subject.keyword | FP-CIT | - |
dc.subject.keyword | Hyposmia | - |
dc.subject.keyword | Parkinson's disease | - |
dc.contributor.alternativeName | Hong, Jin Yong | - |
dc.contributor.alternativeName | Sunwoo, Mun Kyung | - |
dc.contributor.alternativeName | Sohn, Young Ho | - |
dc.contributor.alternativeName | Lee, Ji Eun | - |
dc.contributor.alternativeName | Lee, Phil Hyu | - |
dc.contributor.affiliatedAuthor | Hong, Jin Yong | - |
dc.contributor.affiliatedAuthor | Sunwoo, Mun Kyung | - |
dc.contributor.affiliatedAuthor | Sohn, Young Ho | - |
dc.contributor.affiliatedAuthor | Lee, Phil Hyu | - |
dc.contributor.affiliatedAuthor | Lee, Ji Eun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 19 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1018 | - |
dc.citation.endPage | 1021 | - |
dc.identifier.bibliographicCitation | PARKINSONISM & RELATED DISORDERS, Vol.19(11) : 1018-1021, 2013 | - |
dc.identifier.rimsid | 33910 | - |
dc.type.rims | ART | - |
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