Cited 13 times in
Combined bilateral anterior cingulotomy and ventral capsule/ventral striatum deep brain stimulation for refractory obsessive-compulsive disorder with major depression: Do combined procedures have a long-term benefit?
DC Field | Value | Language |
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dc.contributor.author | 김찬형 | - |
dc.contributor.author | 노대영 | - |
dc.contributor.author | 장원석 | - |
dc.contributor.author | 장진우 | - |
dc.date.accessioned | 2014-12-18T09:48:35Z | - |
dc.date.available | 2014-12-18T09:48:35Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0922-6028 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88871 | - |
dc.description.abstract | Background: The ventral capsule (VC), ventral striatum (VS), and the anterior cingulate gyrus are parts of the obsessive-compulsive disorder (OCD) and depression circuits. We assessed whether a combination of bilateral anterior cingulotomy and VC/VS deep brain stimulation (DBS) had an additive effect in patients with OCD and major depression. Methods: Three patients with refractory OCD underwent combined bilateral anterior cingulotomy and VC/VS DBS procedures. All patients met the inclusion criteria for the Korean guidelines of DBS for OCD. Baseline Yale-Brown Obsessive-Compulsive Disorder Scale (Y-BOCS) scores, Hamilton Depression Rating Scale scores, and global assessments of functioning were evaluated. These scores were also serially estimated for more than 24 months after surgery at 3-month intervals. Results: The mean value of the baseline Y-BOCS scores was 34.7 (range 30–38); the mean Y-BOCS value decreased significantly to 23.0 (range 20–25) 3 months after the surgery. This score was maintained 2 years after surgery with a mean value of 19.0 (range 18–20). Conclusions: The combination of the two therapies did not yield superior outcomes, as the clinical outcomes were comparable to those of previous reports for VC/VS DBS alone. Wide-area VC/VS DBS may be sufficient to control refractory OCD. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | RESTORATIVE NEUROLOGY AND NEUROSCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Basal Ganglia/physiology* | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Deep Brain Stimulation/adverse effects | - |
dc.subject.MESH | Deep Brain Stimulation/methods* | - |
dc.subject.MESH | Depressive Disorder, Major/complications | - |
dc.subject.MESH | Depressive Disorder, Major/psychology | - |
dc.subject.MESH | Depressive Disorder, Major/therapy* | - |
dc.subject.MESH | Diagnostic and Statistical Manual of Mental Disorders | - |
dc.subject.MESH | Electrodes, Implanted | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gyrus Cinguli/physiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neural Pathways/physiology | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/complications | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/psychology | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/therapy* | - |
dc.subject.MESH | Psychiatric Status Rating Scales | - |
dc.subject.MESH | Stereotaxic Techniques | - |
dc.subject.MESH | Thalamus/physiology | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Combined bilateral anterior cingulotomy and ventral capsule/ventral striatum deep brain stimulation for refractory obsessive-compulsive disorder with major depression: Do combined procedures have a long-term benefit? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | Won Seok Chang | - |
dc.contributor.googleauthor | Daeyoung Roh | - |
dc.contributor.googleauthor | Chan-Hyung Kim | - |
dc.contributor.googleauthor | Jin Woo Chang | - |
dc.identifier.doi | 10.3233/RNN-120290 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01036 | - |
dc.contributor.localId | A01276 | - |
dc.contributor.localId | A03484 | - |
dc.contributor.localId | A03454 | - |
dc.relation.journalcode | J02619 | - |
dc.identifier.eissn | 1878-3627 | - |
dc.identifier.pmid | 23979095 | - |
dc.identifier.url | http://iospress.metapress.com/content/08110v5654596615/?genre=article&issn=0922-6028&volume=31&issue=6&spage=723 | - |
dc.subject.keyword | Brain stimulation | - |
dc.subject.keyword | depression | - |
dc.subject.keyword | obsessive-compulsive disorder | - |
dc.subject.keyword | treatment resistant | - |
dc.contributor.alternativeName | Kim, Chan Hyung | - |
dc.contributor.alternativeName | Roh, Dae Young | - |
dc.contributor.alternativeName | Chang, Won Seok | - |
dc.contributor.alternativeName | Chang, Jin Woo | - |
dc.contributor.affiliatedAuthor | Kim, Chan Hyung | - |
dc.contributor.affiliatedAuthor | Roh, Dae Young | - |
dc.contributor.affiliatedAuthor | Chang, Jin Woo | - |
dc.contributor.affiliatedAuthor | Chang, Won Seok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 31 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 723 | - |
dc.citation.endPage | 732 | - |
dc.identifier.bibliographicCitation | RESTORATIVE NEUROLOGY AND NEUROSCIENCE, Vol.31(6) : 723-732, 2013 | - |
dc.identifier.rimsid | 33680 | - |
dc.type.rims | ART | - |
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