Cited 8 times in
Prognostic Value of Metabolic Activity Measured by 18F-FDG PET/CT in Patients with Advanced Endometrial Cancer
DC Field | Value | Language |
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dc.contributor.author | 강원준 | - |
dc.contributor.author | 김영태 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 이재훈 | - |
dc.contributor.author | 이종두 | - |
dc.contributor.author | 조응혁 | - |
dc.date.accessioned | 2014-12-18T09:47:55Z | - |
dc.date.available | 2014-12-18T09:47:55Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1869-3474 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88850 | - |
dc.description.abstract | Purpose We evaluated the potential prognostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with stage IIIC/IV endometrial cancer. Methods Patients with stage IIIC/IV endometrial cancer who had undergone FDG PET/CT workup for staging were enrolled. Maximum standardized uptake values (SUVmax) measured from regions of interest (ROIs) of the primary tumor (SUVt) and lymph nodes (SUVn) were correlated with overall survival (OS). The SUVn was defined as the highest SUVmax of the metastatic lymph nodes. Survival probability was assessed using the Kaplan-Meier method. Results A total of 42 patients with a median age of 55.5 years (range 32–76 years) were included. Twenty-nine percent (n = 12) of patients were premenopausal and 71 % (n = 30) were postmenopausal. The average SUVt was 12.9 (range 1.8–36.5), and the average SUVn was 7.3 (range 2.0–22.5). Median follow-up time was 25.9 months (range 1–84 months). Using a SUVt of 9.5 as a cutoff value, two groups with different rates were determined (P = 0.026). In addition, patients with a low SUVn had significantly better OS than those with a high SUVn (P = 0.003). Patients in the International Federation of Obstetrics and Gynecology (FIGO) stage IV group with SUVt ≥ 9.5 or SUVn ≥ 7.3 showed a significantly longer OS than the other groups. Conclusions FDG uptake of primary endometrial cancer and lymph nodes might be a prognostic factor in advanced endometrial cancer. More aggressive therapy could be considered in patients with stage IV endometrial cancer and high SUVt and/or high SUVn. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | NUCLEAR MEDICINE AND MOLECULAR IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Prognostic Value of Metabolic Activity Measured by 18F-FDG PET/CT in Patients with Advanced Endometrial Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | Hyun Jeong Kim | - |
dc.contributor.googleauthor | Jiyoun Choi | - |
dc.contributor.googleauthor | Yong Hyu Jeong | - |
dc.contributor.googleauthor | Kwan Hyeong Jo | - |
dc.contributor.googleauthor | Jae-Hoon Lee | - |
dc.contributor.googleauthor | Arthur Cho | - |
dc.contributor.googleauthor | Mijin Yun | - |
dc.contributor.googleauthor | Jong Doo Lee | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Won Jun Kang | - |
dc.identifier.doi | 10.1007/s13139-013-0228-2 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A03093 | - |
dc.contributor.localId | A00062 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A03138 | - |
dc.contributor.localId | A03887 | - |
dc.contributor.localId | A05554 | - |
dc.relation.journalcode | J02383 | - |
dc.identifier.eissn | 1869-3482 | - |
dc.identifier.pmid | 24900121 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs13139-013-0228-2 | - |
dc.subject.keyword | Endometrial cancer | - |
dc.subject.keyword | Fluorodeoxyglucose | - |
dc.subject.keyword | PET | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Kang, Won Jun | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.alternativeName | Yun, Mi Jin | - |
dc.contributor.alternativeName | Lee, Jae Hoon | - |
dc.contributor.alternativeName | Lee, Jong Doo | - |
dc.contributor.alternativeName | Cho, Arthur Eung Hyuck | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Lee, Jae Hoon | - |
dc.contributor.affiliatedAuthor | Kang, Won Jun | - |
dc.contributor.affiliatedAuthor | Yun, Mi Jin | - |
dc.contributor.affiliatedAuthor | Lee, Jong Doo | - |
dc.contributor.affiliatedAuthor | Cho, Arthur Eung Hyuck | - |
dc.contributor.affiliatedAuthor | Jeong, Yong Hyu | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 47 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 257 | - |
dc.citation.endPage | 262 | - |
dc.identifier.bibliographicCitation | NUCLEAR MEDICINE AND MOLECULAR IMAGING, Vol.47(4) : 257-262, 2013 | - |
dc.identifier.rimsid | 33664 | - |
dc.type.rims | ART | - |
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