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Serological investigation of Ureaplasma urealyticum in Korean preterm infants

DC Field Value Language
dc.contributor.author박국인-
dc.contributor.author박민수-
dc.contributor.author은호선-
dc.contributor.author이순민-
dc.contributor.author이철-
dc.contributor.author남궁란-
dc.date.accessioned2014-12-18T09:47:12Z-
dc.date.available2014-12-18T09:47:12Z-
dc.date.issued2013-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/88827-
dc.description.abstractPurpose: Ureaplasma colonization is related with perinatal complications in preterm infants. Little is known about the difference in virulence among various Ureaplasma urealyticum serovars. The aim of this study was to determine U. urealyticum serovars of preterm infants in order to assess whether any of the serovars were associated with bronchopulmonary dysplasia (BPD). Methods: Three hundred forty-four preterm infants with a gestational age less than 34 weeks admitted to Gangnam Severance Hospital neonatal intensive care unit from July 2011 to December 2012 were included in this study. Tracheal and gastric aspirations were conducted on infants to confirm Ureaplasma colonization. Ureaplasma colonization was confirmed in 9% of infants, of these, serovars were determined by real-time polymerase chain reaction. Results: A total of 31 infants (gestational age, 29.3±3.1 weeks; birth weight, 1,170±790 g) were U. urealyticum positive. The Ureaplasma positive group treated for more days with oxygen and ventilation than the negative group (P<0.05). Histologic chorioamnionitis and moderate to severe BPD were more frequent in the Ureaplasma positive group than in the negative group (P<0.05). U. urealyticum isolates were either found to be a mixture of multiple serovars (32%), serovar 9 alone or combined with other serovars (39%), serovar 11 (26%), 2 (13%), 8 (10%), 10 (13%), and 13 (25%). No individual serovars were significantly associated with moderate to severe BPD and chorioamnionitis. Conclusion: This is the first study to describe the distribution of U. urealyticum serovars from Korean preterm infants. Ureaplasma -colonized infants showed higher incidence of BPD and chorioamnionitis.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한소아과학회-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSerological investigation of Ureaplasma urealyticum in Korean preterm infants-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorHo Seon Eun-
dc.contributor.googleauthorSoon Min Lee-
dc.contributor.googleauthorMin Soo Park-
dc.contributor.googleauthorKook In Park-
dc.contributor.googleauthorRan Namgung-
dc.contributor.googleauthorChul Lee-
dc.identifier.doi10.3345/kjp.2013.56.11.477-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01438-
dc.contributor.localIdA01468-
dc.contributor.localIdA02635-
dc.contributor.localIdA02905-
dc.contributor.localIdA03253-
dc.contributor.localIdA01241-
dc.relation.journalcodeJ02100-
dc.identifier.eissn2092-7258-
dc.identifier.pmid24348660-
dc.subject.keywordBronchopulmonary dysplasia-
dc.subject.keywordSerovar-
dc.subject.keywordUreaplasma urealyticum-
dc.contributor.alternativeNamePark, Kook In-
dc.contributor.alternativeNamePark, Min Soo-
dc.contributor.alternativeNameEun, Ho Seon-
dc.contributor.alternativeNameLee, Soon Min-
dc.contributor.alternativeNameLee, Chul-
dc.contributor.alternativeNameNamgung, Ran-
dc.contributor.affiliatedAuthorPark, Kook In-
dc.contributor.affiliatedAuthorPark, Min Soo-
dc.contributor.affiliatedAuthorEun, Ho Seon-
dc.contributor.affiliatedAuthorLee, Soon Min-
dc.contributor.affiliatedAuthorLee, Chul-
dc.contributor.affiliatedAuthorNamgung, Ran-
dc.rights.accessRightsfree-
dc.citation.volume56-
dc.citation.number11-
dc.citation.startPage477-
dc.citation.endPage481-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.56(11) : 477-481, 2013-
dc.identifier.rimsid33646-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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