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HIV antiretroviral resistance mutations among antiretroviral treatment-naive and -experienced patients in South Korea

DC Field Value Language
dc.contributor.author김재경-
dc.contributor.author김준명-
dc.contributor.author송영구-
dc.contributor.author송제은-
dc.contributor.author안진영-
dc.contributor.author안혜원-
dc.contributor.author오동현-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.contributor.author최흔-
dc.contributor.author한상훈-
dc.contributor.author구남수-
dc.contributor.author김민형-
dc.contributor.author김선빈-
dc.contributor.author김용찬-
dc.date.accessioned2014-12-18T09:42:01Z-
dc.date.available2014-12-18T09:42:01Z-
dc.date.issued2013-
dc.identifier.issn0889-2229-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/88661-
dc.description.abstractThe purpose of this study was to assess the prevalence and characteristics of HIV drug resistance mutations among antiretroviral therapy (ART)-naive and ART-experienced patients in South Korea. A total of 50 ART-naive and 34 ART-experienced Korean HIV-1-infected patients who visited an urban hospital from February 2007 to March 2011 were included. Most patients (86.9%) were infected with clade B HIV-1. Six (12%) ART-naive and 22 (64.7%) ART-experienced patients had HIV strains with resistance mutations. Among ART-naive patients, V179D was the most common mutation, being found in five ART-naive patients. Among ART-experienced patients, M184V was the most common mutation. Eight of 34 ART-experienced patients had thymidine analogue mutations (TAMs). The prevalence of drug-resistant HIV-1 in ART-naive patients was higher than in previous reports, and 50% of patients with virologic failure harbored strains with multiple resistance mutations. HIV drug resistance testing should be recommended to guide therapy of ART-naive patients in South Korea-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfAIDS RESEARCH AND HUMAN RETROVIRUSES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAnti-HIV Agents/therapeutic use*-
dc.subject.MESHDrug Resistance, Viral/genetics*-
dc.subject.MESHFemale-
dc.subject.MESHHIV Infections/drug therapy*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMutation*-
dc.subject.MESHRepublic of Korea-
dc.titleHIV antiretroviral resistance mutations among antiretroviral treatment-naive and -experienced patients in South Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorMin Hyung Kim-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorYong Chan Kim-
dc.contributor.googleauthorDong Hyun Oh-
dc.contributor.googleauthorHeun Choi-
dc.contributor.googleauthorHea Won Ann-
dc.contributor.googleauthorJae Kyoung Kim-
dc.contributor.googleauthorSun Bean Kim-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorJune Myung Kim-
dc.contributor.googleauthorJun Yong Choi-
dc.identifier.doi10.1089/aid.2013.0184-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00856-
dc.contributor.localIdA00953-
dc.contributor.localIdA02037-
dc.contributor.localIdA02059-
dc.contributor.localIdA02267-
dc.contributor.localIdA02275-
dc.contributor.localIdA02361-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.contributor.localIdA04227-
dc.contributor.localIdA04286-
dc.contributor.localIdA00189-
dc.contributor.localIdA00480-
dc.contributor.localIdA00547-
dc.contributor.localIdA00752-
dc.relation.journalcodeJ00055-
dc.identifier.eissn1931-8405-
dc.identifier.pmid23952717-
dc.identifier.urlhttp://online.liebertpub.com/doi/abs/10.1089/aid.2013.0184-
dc.subject.keywordAdult-
dc.subject.keywordAnti-HIV Agents/therapeutic use*-
dc.subject.keywordDrug Resistance, Viral/genetics*-
dc.subject.keywordFemale-
dc.subject.keywordHIV Infections/drug therapy*-
dc.subject.keywordHumans-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordMutation*-
dc.subject.keywordRepublic of Korea-
dc.contributor.alternativeNameKim, Jae Kyoung-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameAnn, Hea Won-
dc.contributor.alternativeNameOh, Dong Hyun-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameChoi, Heun-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameKim, Min Hyung-
dc.contributor.alternativeNameKim, Sun Bean-
dc.contributor.alternativeNameKim, Yong Chan-
dc.contributor.affiliatedAuthorKim, Jae Kyoung-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorSong, Je Eun-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorAnn, Hea Won-
dc.contributor.affiliatedAuthorOh, Dong Hyun-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorChoi, Heun-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.contributor.affiliatedAuthorKim, Min Hyung-
dc.contributor.affiliatedAuthorKim, Sun Bean-
dc.contributor.affiliatedAuthorKim, Yong Chan-
dc.rights.accessRightsnot free-
dc.citation.volume29-
dc.citation.number12-
dc.citation.startPage1617-
dc.citation.endPage1620-
dc.identifier.bibliographicCitationAIDS RESEARCH AND HUMAN RETROVIRUSES, Vol.29(12) : 1617-1620, 2013-
dc.identifier.rimsid33390-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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