Cited 18 times in
HIV antiretroviral resistance mutations among antiretroviral treatment-naive and -experienced patients in South Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김재경 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 송제은 | - |
dc.contributor.author | 안진영 | - |
dc.contributor.author | 안혜원 | - |
dc.contributor.author | 오동현 | - |
dc.contributor.author | 정수진 | - |
dc.contributor.author | 최준용 | - |
dc.contributor.author | 최흔 | - |
dc.contributor.author | 한상훈 | - |
dc.contributor.author | 구남수 | - |
dc.contributor.author | 김민형 | - |
dc.contributor.author | 김선빈 | - |
dc.contributor.author | 김용찬 | - |
dc.date.accessioned | 2014-12-18T09:42:01Z | - |
dc.date.available | 2014-12-18T09:42:01Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0889-2229 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88661 | - |
dc.description.abstract | The purpose of this study was to assess the prevalence and characteristics of HIV drug resistance mutations among antiretroviral therapy (ART)-naive and ART-experienced patients in South Korea. A total of 50 ART-naive and 34 ART-experienced Korean HIV-1-infected patients who visited an urban hospital from February 2007 to March 2011 were included. Most patients (86.9%) were infected with clade B HIV-1. Six (12%) ART-naive and 22 (64.7%) ART-experienced patients had HIV strains with resistance mutations. Among ART-naive patients, V179D was the most common mutation, being found in five ART-naive patients. Among ART-experienced patients, M184V was the most common mutation. Eight of 34 ART-experienced patients had thymidine analogue mutations (TAMs). The prevalence of drug-resistant HIV-1 in ART-naive patients was higher than in previous reports, and 50% of patients with virologic failure harbored strains with multiple resistance mutations. HIV drug resistance testing should be recommended to guide therapy of ART-naive patients in South Korea | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | AIDS RESEARCH AND HUMAN RETROVIRUSES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anti-HIV Agents/therapeutic use* | - |
dc.subject.MESH | Drug Resistance, Viral/genetics* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | HIV Infections/drug therapy* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Mutation* | - |
dc.subject.MESH | Republic of Korea | - |
dc.title | HIV antiretroviral resistance mutations among antiretroviral treatment-naive and -experienced patients in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Min Hyung Kim | - |
dc.contributor.googleauthor | Je Eun Song | - |
dc.contributor.googleauthor | Jin Young Ahn | - |
dc.contributor.googleauthor | Yong Chan Kim | - |
dc.contributor.googleauthor | Dong Hyun Oh | - |
dc.contributor.googleauthor | Heun Choi | - |
dc.contributor.googleauthor | Hea Won Ann | - |
dc.contributor.googleauthor | Jae Kyoung Kim | - |
dc.contributor.googleauthor | Sun Bean Kim | - |
dc.contributor.googleauthor | Su Jin Jeong | - |
dc.contributor.googleauthor | Nam Su Ku | - |
dc.contributor.googleauthor | Sang Hoon Han | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.identifier.doi | 10.1089/aid.2013.0184 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00856 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A02059 | - |
dc.contributor.localId | A02267 | - |
dc.contributor.localId | A02275 | - |
dc.contributor.localId | A02361 | - |
dc.contributor.localId | A03638 | - |
dc.contributor.localId | A04191 | - |
dc.contributor.localId | A04227 | - |
dc.contributor.localId | A04286 | - |
dc.contributor.localId | A00189 | - |
dc.contributor.localId | A00480 | - |
dc.contributor.localId | A00547 | - |
dc.contributor.localId | A00752 | - |
dc.relation.journalcode | J00055 | - |
dc.identifier.eissn | 1931-8405 | - |
dc.identifier.pmid | 23952717 | - |
dc.identifier.url | http://online.liebertpub.com/doi/abs/10.1089/aid.2013.0184 | - |
dc.subject.keyword | Adult | - |
dc.subject.keyword | Anti-HIV Agents/therapeutic use* | - |
dc.subject.keyword | Drug Resistance, Viral/genetics* | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | HIV Infections/drug therapy* | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Mutation* | - |
dc.subject.keyword | Republic of Korea | - |
dc.contributor.alternativeName | Kim, Jae Kyoung | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Song, Young Goo | - |
dc.contributor.alternativeName | Song, Je Eun | - |
dc.contributor.alternativeName | Ahn, Jin Young | - |
dc.contributor.alternativeName | Ann, Hea Won | - |
dc.contributor.alternativeName | Oh, Dong Hyun | - |
dc.contributor.alternativeName | Jeong, Su Jin | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.alternativeName | Choi, Heun | - |
dc.contributor.alternativeName | Han, Sang Hoon | - |
dc.contributor.alternativeName | Ku, Nam Su | - |
dc.contributor.alternativeName | Kim, Min Hyung | - |
dc.contributor.alternativeName | Kim, Sun Bean | - |
dc.contributor.alternativeName | Kim, Yong Chan | - |
dc.contributor.affiliatedAuthor | Kim, Jae Kyoung | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Song, Young Goo | - |
dc.contributor.affiliatedAuthor | Song, Je Eun | - |
dc.contributor.affiliatedAuthor | Ahn, Jin Young | - |
dc.contributor.affiliatedAuthor | Ann, Hea Won | - |
dc.contributor.affiliatedAuthor | Oh, Dong Hyun | - |
dc.contributor.affiliatedAuthor | Jeong, Su Jin | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Choi, Heun | - |
dc.contributor.affiliatedAuthor | Han, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Ku, Nam Su | - |
dc.contributor.affiliatedAuthor | Kim, Min Hyung | - |
dc.contributor.affiliatedAuthor | Kim, Sun Bean | - |
dc.contributor.affiliatedAuthor | Kim, Yong Chan | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 29 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1617 | - |
dc.citation.endPage | 1620 | - |
dc.identifier.bibliographicCitation | AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol.29(12) : 1617-1620, 2013 | - |
dc.identifier.rimsid | 33390 | - |
dc.type.rims | ART | - |
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