Cited 1 times in
Clinical features of supervoiders who suffer from lower urinary tract symptoms: a propensity score-matching study
DC Field | Value | Language |
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dc.contributor.author | 방우진 | - |
dc.contributor.author | 이승욱 | - |
dc.contributor.author | 이주용 | - |
dc.contributor.author | 조강수 | - |
dc.contributor.author | 함원식 | - |
dc.date.accessioned | 2014-12-18T09:39:43Z | - |
dc.date.available | 2014-12-18T09:39:43Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0724-4983 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88590 | - |
dc.description.abstract | BACKGROUND: Systematic nodal dissection (SND) is regarded as a core component of lung cancer surgery. However, there has been a concern on the increased morbidity associated with SND. This study was performed to investigate whether or not SND induces significant immune response. METHODS: Sixteen dogs were divided into two groups; group 1 (n = 8) underwent thoracotomy only, and group 2 (n = 8) underwent SND after thoracotomy. We compared interleukin-6 (IL-6) levels in serum, pleural lavage fluid and lung supernatant at the time of thoracotomy (T0) and at 2 h(T1) after thoracotomy (group 1) or SND (group 2). Severity of inflammation and IL-6 expression in lung tissue were evaluated in a semi-quantitative manner. RESULTS: The operative results were comparable. IL-6 was not detected in serum in either group. IL-6 in pleural lavage fluid marginally increased from 4.75 ± 3.74 pg/mL at T0 to 19.75 ± 8.67 pg/mL at T1 in group 1 (P = 0.112), and from 7.75 ± 5.35 pg/mL to 17.72 ± 8.58 pg/mL in group 2 (P = 0.068). IL-6 in lung supernatant increased from 0.36 ± 0.14 pg/mL/mg to 1.15 ± 0.17 pg/mL/mg in group 1 (P = 0.003), and from 0.25 ± 0.08 pg/mL/mg to 0.82 ± 0.17 pg/mL/mg in group 2 (P = 0.001). However, the degree of increase in IL-6 in pleural lavage fluid and lung supernatant were not different between two groups (P = 0.421 and P = 0.448). There was no difference in severity of inflammation and IL-6 expression between groups. CONCLUSIONS: SND did not increase IL-6 in pleural lavage fluid and lung supernatant. This result suggests that SND could be routinely performed in lung cancer surgery without increasing the significant inflammatory response. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | WORLD JOURNAL OF UROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Comorbidity | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Lower Urinary Tract Symptoms/epidemiology | - |
dc.subject.MESH | Lower Urinary Tract Symptoms/physiopathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prostatic Hyperplasia/epidemiology | - |
dc.subject.MESH | Prostatic Hyperplasia/physiopathology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Urinary Bladder, Overactive/epidemiology | - |
dc.subject.MESH | Urinary Bladder, Overactive/physiopathology* | - |
dc.subject.MESH | Urination Disorders/epidemiology | - |
dc.subject.MESH | Urination Disorders/physiopathology* | - |
dc.title | Clinical features of supervoiders who suffer from lower urinary tract symptoms: a propensity score-matching study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨기과학) | - |
dc.contributor.googleauthor | Joo Yong Lee | - |
dc.contributor.googleauthor | Yoon Soo Hah | - |
dc.contributor.googleauthor | Dae Hun Lee | - |
dc.contributor.googleauthor | Woo Jin Bang | - |
dc.contributor.googleauthor | Won Sik Ham | - |
dc.contributor.googleauthor | Seung Wook Lee | - |
dc.contributor.googleauthor | Kang Su Cho | - |
dc.identifier.doi | 10.1007/s00345-013-1081-8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01788 | - |
dc.contributor.localId | A02921 | - |
dc.contributor.localId | A03161 | - |
dc.contributor.localId | A03801 | - |
dc.contributor.localId | A04337 | - |
dc.relation.journalcode | J02805 | - |
dc.identifier.eissn | 1433-8726 | - |
dc.identifier.pmid | 23624717 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00345-013-1081-8 | - |
dc.subject.keyword | Lower urinary tract symptoms | - |
dc.subject.keyword | Urinary bladder | - |
dc.subject.keyword | Overactive | - |
dc.subject.keyword | Urinary incontinence | - |
dc.subject.keyword | Urge | - |
dc.contributor.alternativeName | Bang, Woo Jin | - |
dc.contributor.alternativeName | Lee, Seung Wook | - |
dc.contributor.alternativeName | Lee, Joo Yong | - |
dc.contributor.alternativeName | Cho, Kang Su | - |
dc.contributor.alternativeName | Ham, Won Sik | - |
dc.contributor.affiliatedAuthor | Bang, Woo Jin | - |
dc.contributor.affiliatedAuthor | Lee, Seung Wook | - |
dc.contributor.affiliatedAuthor | Lee, Joo Yong | - |
dc.contributor.affiliatedAuthor | Cho, Kang Su | - |
dc.contributor.affiliatedAuthor | Ham, Won Sik | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 31 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1463 | - |
dc.citation.endPage | 1468 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF UROLOGY, Vol.31(6) : 1463-1468, 2013 | - |
dc.identifier.rimsid | 34407 | - |
dc.type.rims | ART | - |
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