Cited 66 times in
Overexpression of Glucose Transporter-1 (GLUT-1) Predicts Poor Prognosis in Epithelial Ovarian Cancer.
DC Field | Value | Language |
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dc.contributor.author | 김재훈 | - |
dc.contributor.author | 조한별 | - |
dc.date.accessioned | 2014-12-18T09:34:55Z | - |
dc.date.available | 2014-12-18T09:34:55Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0735-7907 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88439 | - |
dc.description.abstract | Illumina microarray was used to identify differentially expressed genes in three epithelial ovarian cancer (EOC) cells. To validate the microarray data, mRNA and protein level of glucose transporter-1 (GLUT-1) was examined. GLUT-1 had an EOC/normal cells ratio of 5.51 based on microarray. Real-time PCR and immunohistochemistry demonstrated that GLUT-1 expression was significantly increased in EOC (p = .029 and p < .001, respectively). On survival analysis, GLUT-1 overexpression (HR = 4.80, p = .027) and lymph node metastases (HR = 8.35, p = .016) conferred a significantly worse overall survival. In conclusion, GLUT-1 expression is remarkably upregulated in EOC and predicts a poor overall survival. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | CANCER INVESTIGATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Overexpression of Glucose Transporter-1 (GLUT-1) Predicts Poor Prognosis in Epithelial Ovarian Cancer. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | Hanbyoul Cho | - |
dc.contributor.googleauthor | You Sun Lee | - |
dc.contributor.googleauthor | Julie Kim | - |
dc.contributor.googleauthor | Joon-Yong Chung | - |
dc.contributor.googleauthor | Jae-Hoon Kim | - |
dc.identifier.doi | 10.3109/07357907.2013.849722 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00876 | - |
dc.contributor.localId | A03921 | - |
dc.relation.journalcode | J00446 | - |
dc.identifier.eissn | 1532-4192 | - |
dc.identifier.pmid | GLUT-1 ; Ovarian cancer ; Microarray ; Biomarker ; Immunohistochemistry | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.3109/07357907.2013.849722 | - |
dc.subject.keyword | GLUT-1 | - |
dc.subject.keyword | Ovarian cancer | - |
dc.subject.keyword | Microarray | - |
dc.subject.keyword | Biomarker | - |
dc.subject.keyword | Immunohistochemistry | - |
dc.contributor.alternativeName | Kim, Jae Hoon | - |
dc.contributor.alternativeName | Cho, Han Byoul | - |
dc.contributor.affiliatedAuthor | Kim, Jae Hoon | - |
dc.contributor.affiliatedAuthor | Cho, Han Byoul | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 31 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 607 | - |
dc.citation.endPage | 615 | - |
dc.identifier.bibliographicCitation | CANCER INVESTIGATION, Vol.31(9) : 607-615, 2013 | - |
dc.identifier.rimsid | 34035 | - |
dc.type.rims | ART | - |
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