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Hemoconcentration is a good prognostic predictor for clinical outcomes in acute heart failure: data from the Korean Heart Failure (KorHF) Registry

DC FieldValueLanguage
dc.contributor.author강석민-
dc.contributor.author오재원-
dc.contributor.author윤종찬-
dc.contributor.author홍남기-
dc.date.accessioned2014-12-18T09:33:48Z-
dc.date.available2014-12-18T09:33:48Z-
dc.date.issued2013-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/88403-
dc.description.abstractBACKGROUND: Hemoconcentration is a surrogate marker of effective decongestion and diuresis therapy. Recently, hemoconcentration has been associated with decreased mortality and rehospitalization in heart failure (HF) patients. However, the prognostic power of hemoconcentration in a large sample-sized HF cohort was limited until now. METHODS AND RESULTS: We analyzed data from hospitalized patients with acute heart failure (AHF) that were enrolled in the Korean Heart Failure Registry(n=2,357). The primary end point was a composite of all-cause mortality and HF rehospitalization during the follow-up period (median=347, interquartile range=78-744 days).Hemoconcentration, defined as an increased hemoglobin level between admission and discharge, was presented in 1,016 AHF patients (43.1%). In multivariable logistic regression, hemoglobin, total cholesterol, and serum glucose levels at admission, and ischemic HF, were significant determinants for hemoconcentration occurrence. The Kaplan-Meier curve showed that event-free survival was significantly higher in the hemoconcentration group compared to the non-hemoconcentration group (65.1% vs. 58.1%, log rank p<0.001). In multiple Cox proportional hazard analysis, hemoconcentration was an independent predictor of the primary end point after adjusting for other HF risk factors (hazard ratio=0.671, 95% confidence interval=0.564-0.798, p<0.001). CONCLUSIONS: Hemoconcentration during hospitalization was a prognostic marker of fewer clinical events in the AHF cohort. Therefore, this novel surrogate marker will help in the risk stratification of AHF patients.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfInternational Journal of Cardiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleHemoconcentration is a good prognostic predictor for clinical outcomes in acute heart failure: data from the Korean Heart Failure (KorHF) Registry-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJaewon Oh-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorNamki Hong-
dc.contributor.googleauthorJong-Chan Youn-
dc.contributor.googleauthorSeongwoo Han-
dc.contributor.googleauthorEun-Seok Jeon-
dc.contributor.googleauthorMyeong-Chan Cho-
dc.contributor.googleauthorJae-Joong Kim-
dc.contributor.googleauthorByung-Su Yoo-
dc.contributor.googleauthorShung Chull Chae-
dc.contributor.googleauthorByung-Hee Oh-
dc.contributor.googleauthorDong-Ju Choi-
dc.contributor.googleauthorMyung-Mook Lee-
dc.contributor.googleauthorKyu-Hyung Ryu-
dc.identifier.doi10.1016/j.ijcard.2013.07.241-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00037-
dc.contributor.localIdA02600-
dc.contributor.localIdA04388-
dc.contributor.localIdA02395-
dc.relation.journalcodeJ01093-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0167527313014666-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.alternativeNameOh, Jae Won-
dc.contributor.alternativeNameYoun, Jong Chan-
dc.contributor.alternativeNameHong, Nam Ki-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.contributor.affiliatedAuthorYoun, Jong Chan-
dc.contributor.affiliatedAuthorHong, Namki-
dc.contributor.affiliatedAuthorOh, Jae Won-
dc.rights.accessRightsnot free-
dc.citation.volume168-
dc.citation.number5-
dc.citation.startPage4739-
dc.citation.endPage4743-
dc.identifier.bibliographicCitationInternational Journal of Cardiology, Vol.168(5) : 4739-4743, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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