Cited 28 times in
Hemoconcentration is a good prognostic predictor for clinical outcomes in acute heart failure: data from the Korean Heart Failure (KorHF) Registry
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.contributor.author | 오재원 | - |
dc.contributor.author | 윤종찬 | - |
dc.contributor.author | 홍남기 | - |
dc.date.accessioned | 2014-12-18T09:33:48Z | - |
dc.date.available | 2014-12-18T09:33:48Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0167-5273 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88403 | - |
dc.description.abstract | BACKGROUND: Hemoconcentration is a surrogate marker of effective decongestion and diuresis therapy. Recently, hemoconcentration has been associated with decreased mortality and rehospitalization in heart failure (HF) patients. However, the prognostic power of hemoconcentration in a large sample-sized HF cohort was limited until now. METHODS AND RESULTS: We analyzed data from hospitalized patients with acute heart failure (AHF) that were enrolled in the Korean Heart Failure Registry(n=2,357). The primary end point was a composite of all-cause mortality and HF rehospitalization during the follow-up period (median=347, interquartile range=78-744 days).Hemoconcentration, defined as an increased hemoglobin level between admission and discharge, was presented in 1,016 AHF patients (43.1%). In multivariable logistic regression, hemoglobin, total cholesterol, and serum glucose levels at admission, and ischemic HF, were significant determinants for hemoconcentration occurrence. The Kaplan-Meier curve showed that event-free survival was significantly higher in the hemoconcentration group compared to the non-hemoconcentration group (65.1% vs. 58.1%, log rank p<0.001). In multiple Cox proportional hazard analysis, hemoconcentration was an independent predictor of the primary end point after adjusting for other HF risk factors (hazard ratio=0.671, 95% confidence interval=0.564-0.798, p<0.001). CONCLUSIONS: Hemoconcentration during hospitalization was a prognostic marker of fewer clinical events in the AHF cohort. Therefore, this novel surrogate marker will help in the risk stratification of AHF patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acute Disease | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Biomarkers/blood* | - |
dc.subject.MESH | Cause of Death/trends | - |
dc.subject.MESH | Diuretics/therapeutic use* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Heart Failure/blood* | - |
dc.subject.MESH | Heart Failure/drug therapy | - |
dc.subject.MESH | Heart Failure/mortality | - |
dc.subject.MESH | Hematocrit | - |
dc.subject.MESH | Hemoglobins/metabolism* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Patient Readmission/trends | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Registries* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Survival Rate/trends | - |
dc.subject.MESH | Time Factors | - |
dc.title | Hemoconcentration is a good prognostic predictor for clinical outcomes in acute heart failure: data from the Korean Heart Failure (KorHF) Registry | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jaewon Oh | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Namki Hong | - |
dc.contributor.googleauthor | Jong-Chan Youn | - |
dc.contributor.googleauthor | Seongwoo Han | - |
dc.contributor.googleauthor | Eun-Seok Jeon | - |
dc.contributor.googleauthor | Myeong-Chan Cho | - |
dc.contributor.googleauthor | Jae-Joong Kim | - |
dc.contributor.googleauthor | Byung-Su Yoo | - |
dc.contributor.googleauthor | Shung Chull Chae | - |
dc.contributor.googleauthor | Byung-Hee Oh | - |
dc.contributor.googleauthor | Dong-Ju Choi | - |
dc.contributor.googleauthor | Myung-Mook Lee | - |
dc.contributor.googleauthor | Kyu-Hyung Ryu | - |
dc.identifier.doi | 10.1016/j.ijcard.2013.07.241 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A02600 | - |
dc.contributor.localId | A04388 | - |
dc.contributor.localId | A02395 | - |
dc.relation.journalcode | J01093 | - |
dc.identifier.eissn | 1874-1754 | - |
dc.identifier.pmid | 23958420 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0167527313014666 | - |
dc.subject.keyword | Acute heart failure | - |
dc.subject.keyword | Hemoconcentration | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.alternativeName | Oh, Jae Won | - |
dc.contributor.alternativeName | Youn, Jong Chan | - |
dc.contributor.alternativeName | Hong, Nam Ki | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Youn, Jong Chan | - |
dc.contributor.affiliatedAuthor | Hong, Namki | - |
dc.contributor.affiliatedAuthor | Oh, Jae Won | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 168 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 4739 | - |
dc.citation.endPage | 4743 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.168(5) : 4739-4743, 2013 | - |
dc.identifier.rimsid | 32490 | - |
dc.type.rims | ART | - |
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