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A comparison of the predicted risk for cardiovascular disease between HIV-infected and uninfected persons in Korea.

DC Field Value Language
dc.contributor.author구남수-
dc.contributor.author김민형-
dc.contributor.author김선빈-
dc.contributor.author김용찬-
dc.contributor.author김준명-
dc.contributor.author김혜원-
dc.contributor.author송영구-
dc.contributor.author송제은-
dc.contributor.author안진영-
dc.contributor.author오동현-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.contributor.author한상훈-
dc.date.accessioned2014-12-18T09:29:26Z-
dc.date.available2014-12-18T09:29:26Z-
dc.date.issued2013-
dc.identifier.issn0036-5548-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/88266-
dc.description.abstractBackground: The introduction of highly active antiretroviral therapy (HAART) has extended the life expectancy of persons infected with the human immunodeficiency virus type 1 (HIV-1). However, cardiovascular disease (CVD) is currently an increasing concern for HIV-infected persons. Methods: We conducted a cross-sectional case–control study to evaluate and compare the 10-y cardiovascular risk of HIV-infected Koreans who had been receiving HAART for over 6 months and age- and sex-matched uninfected persons who visited a health promotion center, by calculating Framingham risk scores (FRS). Results: The average 10-y risk for cardiovascular events (FRS) was 7.07% (2–45) in the HIV group and 6.87% (1–37) in the control group (p = 0.77), corresponding to the very low risk group. Among HIV patients, the FRS was above 10% (low to moderate cardiovascular risk) in 19.9% of the patients, and above 20% (high risk) in 1.7% of the patients. In the healthy control group, the FRS was above 10% in 16.8% and above 20% in 2.7% (p = 0.57). The FRS was not significantly different for HIV-infected patients treated with protease inhibitor (PI)-based HAART and those treated with non-nucleoside reverse transcriptase inhibitor (NNRTI)-based HAART (7.26 ± 6.3 and 6.81 ± 4.4, respectively, p = 0.69). Conclusions: The predicted cardiovascular risk of HIV-infected Koreans on HAART by FRS equation was low and similar to that of age- and sex-matched healthy control persons. However, the possibility remains that actual cardiovascular events could be underestimated. The next step for predicting the cardiovascular risk is to calculate the Data Collection of Adverse Events of Anti-HIV Drugs (D:A:D) equation risks.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfSCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAntiretroviral Therapy, Highly Active-
dc.subject.MESHCardiovascular Diseases/epidemiology*-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHIV Infections/complications*-
dc.subject.MESHHIV Infections/drug therapy-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Assessment-
dc.titleA comparison of the predicted risk for cardiovascular disease between HIV-infected and uninfected persons in Korea.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSun Bean Kim-
dc.contributor.googleauthorYong Chan Kim-
dc.contributor.googleauthorMin Hyung Kim-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorDong Hyun Oh-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorHye-won Kim-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorJune Myung Kim-
dc.identifier.doi10.3109/00365548.2013.813064-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00189-
dc.contributor.localIdA00480-
dc.contributor.localIdA00547-
dc.contributor.localIdA00752-
dc.contributor.localIdA00953-
dc.contributor.localIdA01176-
dc.contributor.localIdA02037-
dc.contributor.localIdA02059-
dc.contributor.localIdA02267-
dc.contributor.localIdA02361-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.contributor.localIdA04286-
dc.relation.journalcodeJ02634-
dc.identifier.eissn1651-1980-
dc.identifier.pmid23968223-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/00365548.2013.813064-
dc.subject.keywordFramingham risk score-
dc.subject.keywordHIV-
dc.subject.keywordHAART-
dc.subject.keywordhealthy control group-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameKim, Min Hyung-
dc.contributor.alternativeNameKim, Sun Bean-
dc.contributor.alternativeNameKim, Yong Chan-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Hye Won-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameOh, Dong Hyun-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.contributor.affiliatedAuthorKim, Min Hyung-
dc.contributor.affiliatedAuthorKim, Sun Bean-
dc.contributor.affiliatedAuthorKim, Yong Chan-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorKim, Hye Won-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorSong, Je Eun-
dc.contributor.affiliatedAuthorAhn, Jin Young-
dc.contributor.affiliatedAuthorOh, Dong Hyun-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.rights.accessRightsnot free-
dc.citation.volume45-
dc.citation.number11-
dc.citation.startPage855-
dc.citation.endPage862-
dc.identifier.bibliographicCitationSCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, Vol.45(11) : 855-862, 2013-
dc.identifier.rimsid33168-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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