Cited 14 times in
A Proposal to Prevent the "Mephisto Sign" Side Effect of Botulinum Toxin Type A Injection in Chronic Migraine
DC Field | Value | Language |
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dc.contributor.author | 김성택 | - |
dc.contributor.author | 조은애산드라 | - |
dc.date.accessioned | 2014-12-18T09:23:20Z | - |
dc.date.available | 2014-12-18T09:23:20Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88078 | - |
dc.description.abstract | Botulinum toxin type A (BoNT-A) has been reported as an effective treatment for chronic migraine. When BoNT-A is injected on the frontalis muscle for chronic migraine, an unexpected clinical side effect called the "Mephisto sign" may occur. The aim of this article is to propose a method to eliminate or prevent the Mephisto sign side effect. A 25-year-old female patient visited the hospital and was diagnosed with chronic migraine. A total of 155 U of BoNT-A was injected into 31 sites. 2-weeks later, and the patient developed the Mephisto sign. An additional 2-U dose was administered bilaterally to the lateral-most point of the frontalis muscles, and the eyebrow morphology returned to normal within 2-3 weeks. We propose that the development of the Mephisto sign may be prevented with an additional BoNT-A injection of 2-4 U bilaterally to the lateral most point of the frontalis muscles during the primary injection process. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Botulinum Toxins, Type A/administration & dosage | - |
dc.subject.MESH | Botulinum Toxins, Type A/adverse effects* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Injections | - |
dc.subject.MESH | Migraine Disorders/drug therapy* | - |
dc.title | A Proposal to Prevent the "Mephisto Sign" Side Effect of Botulinum Toxin Type A Injection in Chronic Migraine | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Medicine (구강내과학) | - |
dc.contributor.googleauthor | Eunae S. Cho | - |
dc.contributor.googleauthor | Jae Young Hwang | - |
dc.contributor.googleauthor | Seong Taek Kim | - |
dc.identifier.doi | 10.3349/ymj.2013.54.6.1542 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00588 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 24142664 | - |
dc.subject.keyword | Migraine disorders | - |
dc.subject.keyword | botulinum toxin type A | - |
dc.subject.keyword | eyebrows | - |
dc.contributor.alternativeName | Kim, Seong Taek | - |
dc.contributor.affiliatedAuthor | Kim, Seong Taek | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 54 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1542 | - |
dc.citation.endPage | 1544 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.54(6) : 1542-1544, 2013 | - |
dc.identifier.rimsid | 32748 | - |
dc.type.rims | ART | - |
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