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A Proposal to Prevent the "Mephisto Sign" Side Effect of Botulinum Toxin Type A Injection in Chronic Migraine

DC FieldValueLanguage
dc.contributor.author김성택-
dc.contributor.author조은애산드라-
dc.date.accessioned2014-12-18T09:23:20Z-
dc.date.available2014-12-18T09:23:20Z-
dc.date.issued2013-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/88078-
dc.description.abstractBotulinum toxin type A (BoNT-A) has been reported as an effective treatment for chronic migraine. When BoNT-A is injected on the frontalis muscle for chronic migraine, an unexpected clinical side effect called the "Mephisto sign" may occur. The aim of this article is to propose a method to eliminate or prevent the Mephisto sign side effect. A 25-year-old female patient visited the hospital and was diagnosed with chronic migraine. A total of 155 U of BoNT-A was injected into 31 sites. 2-weeks later, and the patient developed the Mephisto sign. An additional 2-U dose was administered bilaterally to the lateral-most point of the frontalis muscles, and the eyebrow morphology returned to normal within 2-3 weeks. We propose that the development of the Mephisto sign may be prevented with an additional BoNT-A injection of 2-4 U bilaterally to the lateral most point of the frontalis muscles during the primary injection process.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBotulinum Toxins, Type A/administration & dosage-
dc.subject.MESHBotulinum Toxins, Type A/adverse effects*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInjections-
dc.subject.MESHMigraine Disorders/drug therapy*-
dc.titleA Proposal to Prevent the "Mephisto Sign" Side Effect of Botulinum Toxin Type A Injection in Chronic Migraine-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Medicine (구강내과학)-
dc.contributor.googleauthorEunae S. Cho-
dc.contributor.googleauthorJae Young Hwang-
dc.contributor.googleauthorSeong Taek Kim-
dc.identifier.doi10.3349/ymj.2013.54.6.1542-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00588-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid24142664-
dc.subject.keywordMigraine disorders-
dc.subject.keywordbotulinum toxin type A-
dc.subject.keywordeyebrows-
dc.contributor.alternativeNameKim, Seong Taek-
dc.contributor.affiliatedAuthorKim, Seong Taek-
dc.rights.accessRightsfree-
dc.citation.volume54-
dc.citation.number6-
dc.citation.startPage1542-
dc.citation.endPage1544-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.54(6) : 1542-1544, 2013-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers

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