Cited 2 times in
Effect of a single dose of esmolol on the bispectral index to endotracheal intubation during desflurane anesthesia
DC Field | Value | Language |
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dc.contributor.author | 민경태 | - |
dc.contributor.author | 이정림 | - |
dc.contributor.author | 최승호 | - |
dc.date.accessioned | 2014-12-18T09:15:23Z | - |
dc.date.available | 2014-12-18T09:15:23Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/87827 | - |
dc.description.abstract | BACKGROUND: In this prospective, randomized, double-blind, placebo-controlled trial, we investigated the effect of a single dose of esmolol on the bispectral index (BIS) to endotracheal intubation during desflurane anesthesia. METHODS: After induction of anesthesia, 60 patients were mask-ventilated with desflurane (end-tidal 1 minimum alveolar concentration) for 5 min and then received either normal saline, esmolol 0.5 or 1 mg/kg, 1 min prior to intubation (control, esmolol-0.5 and esmolol-1 groups, n = 20/group). BIS, mean arterial pressure, and heart rate were measured prior to anesthesia induction and esmolol administration, immediately preceding intubation (time point 0), and every minute for 5 min after intubation (time point 1 to 5). At time point 0, 1 and 5, 5 ml of arterial blood was taken to measure plasma concentrations of norepinephrine and epinephrine. RESULTS: BIS increased significantly at 1 min after intubation when compared with pre-intubation values in all groups. Both mean arterial pressure and heart rate increased significantly 1 min after intubation when compared with preintubation values for all groups. Plasma epinephrine concentrations did not increase significantly after tracheal intubation in any of the groups. Norepinephrine increased at 1 min after intubation when compared with the preintubation values in the esmolol groups (P < 0.05). CONCLUSIONS: A single bolus of esmolol was unable to blunt the increase in BIS to endotracheal intubation during desflurane anesthesia. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effect of a single dose of esmolol on the bispectral index to endotracheal intubation during desflurane anesthesia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | Eun Mi Choi | - |
dc.contributor.googleauthor | Kyeong Tae Min | - |
dc.contributor.googleauthor | Jeong Rim Lee | - |
dc.contributor.googleauthor | Tai Kyung Lee | - |
dc.contributor.googleauthor | Seung Ho Choi | - |
dc.identifier.doi | 10.4097/kjae.2013.64.5.420 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01400 | - |
dc.contributor.localId | A03098 | - |
dc.contributor.localId | A04101 | - |
dc.relation.journalcode | J01963 | - |
dc.identifier.eissn | 2005-7563 | - |
dc.identifier.pmid | 23741564 | - |
dc.subject.keyword | Bispectral index | - |
dc.subject.keyword | Desflurane | - |
dc.subject.keyword | Esmolol | - |
dc.subject.keyword | Intubation | - |
dc.subject.keyword | Norepinephrine | - |
dc.contributor.alternativeName | Min, Kyeong Tae | - |
dc.contributor.alternativeName | Lee, Jeong Rim | - |
dc.contributor.alternativeName | Choi, Seung Ho | - |
dc.contributor.affiliatedAuthor | Min, Kyeong Tae | - |
dc.contributor.affiliatedAuthor | Lee, Jeong Rim | - |
dc.contributor.affiliatedAuthor | Choi, Seung Ho | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 64 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 420 | - |
dc.citation.endPage | 425 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.64(5) : 420-425, 2013 | - |
dc.identifier.rimsid | 32292 | - |
dc.type.rims | ART | - |
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