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Increasing prevalence of bla(OXA-23)-carrying Acinetobacter baumannii and the emergence of bla(OXA-182)-carrying Acinetobacter nosocomialis in Korea

DC FieldValueLanguage
dc.contributor.author정석훈-
dc.contributor.author정윤섭-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author이양순-
dc.date.accessioned2014-12-18T09:12:22Z-
dc.date.available2014-12-18T09:12:22Z-
dc.date.issued2013-
dc.identifier.issn0732-8893-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87731-
dc.description.abstractCarbapenem-resistant Acinetobacter spp. have been increasingly reported worldwide with the production of OXA-type carbapenemases as the main mechanism of carbapenem resistance. The prevalent bla(OXA) genes are known to vary significantly depending on time and place of isolation. We investigated the prevalence of bla(OXA) genes by PCR in Acinetobacter spp. isolated in Korea. Among a total of 336 isolates collected from Hospital A from 2002 to 2011, the overall proportion of bla(OXA)-23-like, ISAba1-associated bla(OXA-51)-like, and bla(OXA-182) genes were 44.0%, 49.7%, and 5.1%, respectively. The bla(OXA-58)-like gene was detected in only 1 isolate. A drastic increase in Acinetobacter isolates with bla(OXA-23)-like genes and a decrease in isolates harboring ISAba1-associated bla(OXA-51)-like genes have been observed since the mid-2000s. The bla(OXA-23)-like genes were detected in all carbapenem-nonsusceptible isolates collected in 2011 from 9 hospitals. The OXA-182, which belongs to the fifth group of OXA-type carbapenemase, was detected in Acinetobacter baumannii isolates recovered as early as 2002. It is worrisome results that bla(OXA-182)-carrying Acinetobacter nosocomialis has emerged and caused outbreaks of infection.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfDIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcinetobacter Infections/epidemiology-
dc.subject.MESHAcinetobacter Infections/microbiology*-
dc.subject.MESHAcinetobacter baumannii/drug effects-
dc.subject.MESHAcinetobacter baumannii/enzymology*-
dc.subject.MESHAcinetobacter baumannii/genetics-
dc.subject.MESHAcinetobacter baumannii/isolation & purification-
dc.subject.MESHAnti-Bacterial Agents/pharmacology-
dc.subject.MESHBacterial Proteins/biosynthesis-
dc.subject.MESHBacterial Proteins/genetics-
dc.subject.MESHCross Infection/epidemiology-
dc.subject.MESHCross Infection/microbiology*-
dc.subject.MESHHumans-
dc.subject.MESHMicrobial Sensitivity Tests-
dc.subject.MESHPhylogeny-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHbeta-Lactam Resistance/genetics-
dc.subject.MESHbeta-Lactamases/biosynthesis*-
dc.subject.MESHbeta-Lactamases/genetics-
dc.titleIncreasing prevalence of bla(OXA-23)-carrying Acinetobacter baumannii and the emergence of bla(OXA-182)-carrying Acinetobacter nosocomialis in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorYangsoon Lee-
dc.contributor.googleauthorYoung-Ree Kim-
dc.contributor.googleauthorJayoung Kim-
dc.contributor.googleauthorYeon-Joon Park-
dc.contributor.googleauthorWonkeun Song-
dc.contributor.googleauthorJong-Hee Shin-
dc.contributor.googleauthorYoung Uh-
dc.contributor.googleauthorKyutaeg Lee-
dc.contributor.googleauthorSeong Hee Lee-
dc.contributor.googleauthorJi Hyun Cho-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorSeok Hoon Jeong-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorYunsop Chong-
dc.identifier.doi10.1016/j.diagmicrobio.2013.06.009-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03619-
dc.contributor.localIdA03679-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA02947-
dc.relation.journalcodeJ00731-
dc.identifier.eissn1879-0070-
dc.identifier.pmid23891219-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0732889313003416-
dc.subject.keywordAcinetobacter baumannii-
dc.subject.keywordAcinetobacter nosocomialis-
dc.subject.keywordbla(OXA-182)-
dc.subject.keywordbla(OXA-23)-
dc.contributor.alternativeNameJeong, Seok Hoon-
dc.contributor.alternativeNameChong, Yun Sop-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameLee, Yang Soon-
dc.contributor.affiliatedAuthorJeong, Seok Hoon-
dc.contributor.affiliatedAuthorChong, Yun Sop-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorLee, Yang Soon-
dc.rights.accessRightsnot free-
dc.citation.volume77-
dc.citation.number2-
dc.citation.startPage160-
dc.citation.endPage163-
dc.identifier.bibliographicCitationDIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.77(2) : 160-163, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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