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Comparison of the Effects of Normal Saline Versus Plasmalyte on Acid-Base Balance During Living Donor Kidney Transplantation Using the Stewart and Base Excess Methods

DC FieldValueLanguage
dc.contributor.author김소연-
dc.contributor.author김신형-
dc.contributor.author이정림-
dc.contributor.author최용선-
dc.contributor.author허규하-
dc.contributor.author정승호-
dc.date.accessioned2014-12-18T09:10:37Z-
dc.date.available2014-12-18T09:10:37Z-
dc.date.issued2013-
dc.identifier.issn0041-1345-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87676-
dc.description.abstractBACKGROUND: Ischemia-reperfusion injury is an inevitable consequence of kidney transplantation, leading to metabolic acidosis. This study compared the effects of normal saline (NS) and Plasmalyte on acid-base balance and electrolytes during living donor kidney transplantation using the Stewart and base excess (BE) methods. METHODS: Patients were randomized to an NS group (n = 30) or a Plasmalyte group (n = 30). Arterial blood samples were collected for acid-base analysis after induction of anesthesia (T0), prior to clamping the iliac vein (T1), 10 minutes after reperfusion of the donated kidney (T2), and at the end of surgery (T3). In addition serum creatinine and 24-hour urine output were recorded on postoperative days 1,2, and 7. Over the first postoperative 7 days we recorded episodes of graft failure requiring dialysis. RESULTS: Compared with the Plasmalyte group, the NS group showed significantly lower values of pH, BE, and effective strong ion differences during the postreperfusion period (T2 and T3). Chloride-related values (chloride [Cl(-)], free-water corrected Cl(-), BEcl) were significantly higher at T1, T2, and T3, indicating hyperchloremic rather than dilutional metabolic acidosis. Early postoperative graft functions in terms of serum creatinine, urine output, and graft failure requiring dialysis were not significantly different between the groups. CONCLUSIONS: Both NS and Plamalyte can be used safely during uncomplicated living donor kidney transplantation. However, Plasmalyte more stably maintains acid-base and electrolyte balance compared with NS especially during the postreperfusion period.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfTRANSPLANTATION PROCEEDINGS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcid-Base Equilibrium/drug effects*-
dc.subject.MESHAcidosis/blood-
dc.subject.MESHAcidosis/etiology-
dc.subject.MESHAcidosis/physiopathology-
dc.subject.MESHAcidosis/prevention & control*-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCreatinine/blood-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHElectrolytes/administration & dosage*-
dc.subject.MESHElectrolytes/adverse effects-
dc.subject.MESHFemale-
dc.subject.MESHFluid Therapy/adverse effects-
dc.subject.MESHFluid Therapy/methods*-
dc.subject.MESHGraft Survival/drug effects-
dc.subject.MESHHumans-
dc.subject.MESHHydrogen-Ion Concentration-
dc.subject.MESHKidney Transplantation/adverse effects-
dc.subject.MESHKidney Transplantation/methods*-
dc.subject.MESHLiving Donors*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPlasma Substitutes/administration & dosage*-
dc.subject.MESHPlasma Substitutes/adverse effects-
dc.subject.MESHRenal Dialysis-
dc.subject.MESHReperfusion Injury/blood-
dc.subject.MESHReperfusion Injury/etiology-
dc.subject.MESHReperfusion Injury/physiopathology-
dc.subject.MESHReperfusion Injury/prevention & control*-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHSodium Chloride/administration & dosage*-
dc.subject.MESHSodium Chloride/adverse effects-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUrination-
dc.subject.MESHYoung Adult-
dc.titleComparison of the Effects of Normal Saline Versus Plasmalyte on Acid-Base Balance During Living Donor Kidney Transplantation Using the Stewart and Base Excess Methods-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorS.Y. Kim-
dc.contributor.googleauthorK.H. Huh-
dc.contributor.googleauthorJ.R. Lee-
dc.contributor.googleauthorS.H. Kim-
dc.contributor.googleauthorS.H. Jeong-
dc.contributor.googleauthorY.S. Choi-
dc.identifier.doi10.1016/j.transproceed.2013.02.124-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00676-
dc.contributor.localIdA03098-
dc.contributor.localIdA04119-
dc.contributor.localIdA04344-
dc.contributor.localIdA00616-
dc.relation.journalcodeJ02755-
dc.identifier.eissn1873-2623-
dc.identifier.pmid23953528-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0041134513004995-
dc.subject.keywordAcid-Base Equilibrium/drug effects*-
dc.subject.keywordAcidosis/blood-
dc.subject.keywordAcidosis/etiology-
dc.subject.keywordAcidosis/physiopathology-
dc.subject.keywordAcidosis/prevention & control*-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordBiomarkers/blood-
dc.subject.keywordCreatinine/blood-
dc.subject.keywordDouble-Blind Method-
dc.subject.keywordElectrolytes/administration & dosage*-
dc.subject.keywordElectrolytes/adverse effects-
dc.subject.keywordFemale-
dc.subject.keywordFluid Therapy/adverse effects-
dc.subject.keywordFluid Therapy/methods*-
dc.subject.keywordGraft Survival/drug effects-
dc.subject.keywordHumans-
dc.subject.keywordHydrogen-Ion Concentration-
dc.subject.keywordKidney Transplantation/adverse effects-
dc.subject.keywordKidney Transplantation/methods*-
dc.subject.keywordLiving Donors*-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPlasma Substitutes/administration & dosage*-
dc.subject.keywordPlasma Substitutes/adverse effects-
dc.subject.keywordRenal Dialysis-
dc.subject.keywordReperfusion Injury/blood-
dc.subject.keywordReperfusion Injury/etiology-
dc.subject.keywordReperfusion Injury/physiopathology-
dc.subject.keywordReperfusion Injury/prevention & control*-
dc.subject.keywordRepublic of Korea-
dc.subject.keywordSodium Chloride/administration & dosage*-
dc.subject.keywordSodium Chloride/adverse effects-
dc.subject.keywordTime Factors-
dc.subject.keywordTreatment Outcome-
dc.subject.keywordUrination-
dc.subject.keywordYoung Adult-
dc.contributor.alternativeNameKim, So Yeon-
dc.contributor.alternativeNameKim, Shin Hyung-
dc.contributor.alternativeNameLee, Jeong Rim-
dc.contributor.alternativeNameChoi, Yong Seon-
dc.contributor.alternativeNameHuh, Kyu Ha-
dc.contributor.affiliatedAuthorKim, Shin Hyung-
dc.contributor.affiliatedAuthorLee, Jeong Rim-
dc.contributor.affiliatedAuthorChoi, Yong Seon-
dc.contributor.affiliatedAuthorHuh, Kyu Ha-
dc.contributor.affiliatedAuthorKim, So Yeon-
dc.rights.accessRightsnot free-
dc.citation.volume45-
dc.citation.number6-
dc.citation.startPage2191-
dc.citation.endPage2196-
dc.identifier.bibliographicCitationTRANSPLANTATION PROCEEDINGS, Vol.45(6) : 2191-2196, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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