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아토피피부염과 피부 장벽 이상

DC Field Value Language
dc.contributor.author신정우-
dc.contributor.author이광훈-
dc.date.accessioned2014-12-18T09:06:40Z-
dc.date.available2014-12-18T09:06:40Z-
dc.date.issued2013-
dc.identifier.issn2288-0402-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87554-
dc.description.abstractAtopic dermatitis is a chronic relapsing eczematous dermatosis, which usually starts in childhood, and various causes are intricately associated with the development of the disease. Recently, various abnormalities in barrier function have been identified as the cause of atopic dermatitis. Loss-of-function mutation of filaggrin, a significant constituent of skin barrier, has been revealed as a cause for atopic dermatitis, and factors like enhanced protease activity, and decreased synthesis of the lipid lamellae especially ceramides also plays an important role in barrier dysfunction. Not only these genetic causes but also environmental factors are associated in barrier dysfunction, such as soap or detergents which increases skin pH, or proteases of dust mites or cockroaches which enhances epidermal barrier breakdown. Lately, skin barrier dysfunction is also thought to play an important role in the early stage of other allergic diseases such as asthma. Therefore, comprehension of the function of skin barrier can provide help in understanding various allergic diseases.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfALLERGY ASTHMA & RESPIRATORY DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title아토피피부염과 피부 장벽 이상-
dc.title.alternativeAtopic dermatitis and skin barrier dysfunction-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Dermatology (피부과학)-
dc.contributor.googleauthor김현정-
dc.contributor.googleauthor신정우-
dc.contributor.googleauthor이광훈-
dc.identifier.doi10.4168/aard.2013.1.1.20-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02149-
dc.contributor.localIdA02674-
dc.relation.journalcodeJ00065-
dc.identifier.pmidAtopic dermatitis ; Skin barrier ; Filaggrin ; Ceramide-
dc.subject.keywordAtopic dermatitis-
dc.subject.keywordSkin barrier-
dc.subject.keywordFilaggrin-
dc.subject.keywordCeramide-
dc.contributor.alternativeNameShin, Jung U-
dc.contributor.alternativeNameLee, Kwang Hoon-
dc.contributor.affiliatedAuthorShin, Jung U-
dc.contributor.affiliatedAuthorLee, Kwang Hoon-
dc.rights.accessRightsfree-
dc.citation.volume1-
dc.citation.number1-
dc.citation.startPage20-
dc.citation.endPage28-
dc.identifier.bibliographicCitationALLERGY ASTHMA & RESPIRATORY DISEASE, Vol.1(1) : 20-28, 2013-
dc.identifier.rimsid34304-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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