Cited 114 times in
Prognostic value of myocardial circumferential strain for incident heart failure and cardiovascular events in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최의영 | - |
dc.date.accessioned | 2014-12-18T09:03:54Z | - |
dc.date.available | 2014-12-18T09:03:54Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0195-668X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/87466 | - |
dc.description.abstract | Left ventricular (LV) circumferential strain (Ecc) is a sensitive index of regional myocardial function. Currently, no studies have assessed its prognostic value in general population. We sought to investigate whether Ecc has a prognostic value for predicting incident heart failure (HF) and other major cardiovascular events in asymptomatic individuals without a history of previous cardiovascular diseases. METHODS AND RESULTS: We, prospectively, assessed incident HF and atherosclerotic events during a 5.5 ± 1.3-year period in 1768 asymptomatic individuals aged 45-84 (mean age 65 years; 47% female) who underwent tagged magnetic resonance imaging for strain determination. During the follow-up period, 39 (2.2%) participants experienced incident HF and 108 (6.1%) participants had atherosclerotic cardiovascular events. Average of peak Ecc of 12-LV segments (Ecc-global) and mid-slice (Ecc-mid) was -17.0 ± 2.4 and -17.5 ± 2.7%, respectively. Participants with average absolute Ecc-mid lower than -16.9% had a higher cumulative hazard of incident HF (log-rank test, P = 0.001). In cox regression analysis, Ecc-mid predicted incident HF independent of age, diabetes status, hypertension, interim myocardial infarction, LV mass index, and LV ejection fraction (hazard ratio 1.15 per 1%, 95% CI: 1.01-1.31, P = 0.03). This relationship remained significant after adjustment for LV-end-systolic wall stress into covariates. In addition, by adding Ecc-mid to risk factors, LV ejection fraction, and the LV mass index, both the global χ(2) value (76.6 vs. 82.4, P = 0.04) and category-less net-reclassification index (P = 0.01, SE = 0.18, z = 2.53) were augmented for predicting HF. Circumferential strain was also significantly related to the composite atherosclerotic cardiovascular events, but its relationship was attenuated after introducing the LV mass index. CONCLUSION: Circumferential shortening provides robust, independent, and incremental predictive value for incident HF in asymptomatic subjects without any history of previous clinical cardiovascular disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | EUROPEAN HEART JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Atherosclerosis/etiology* | - |
dc.subject.MESH | Atherosclerosis/physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Failure/etiology* | - |
dc.subject.MESH | Heart Failure/physiopathology | - |
dc.subject.MESH | Heart Rate/physiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Angiography | - |
dc.subject.MESH | Magnetic Resonance Imaging, Cine | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Contraction/physiology | - |
dc.subject.MESH | Myocardial Infarction/etiology | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prosthesis Failure | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Stress, Physiological/physiology | - |
dc.subject.MESH | Stroke Volume/physiology | - |
dc.subject.MESH | Ventricular Dysfunction, Left/etiology | - |
dc.subject.MESH | Ventricular Dysfunction, Left/physiopathology | - |
dc.title | Prognostic value of myocardial circumferential strain for incident heart failure and cardiovascular events in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Boaz D. Rosen | - |
dc.contributor.googleauthor | Veronica R.S. Fernandes | - |
dc.contributor.googleauthor | Raymond T. Yan | - |
dc.contributor.googleauthor | Kihei Yoneyama | - |
dc.contributor.googleauthor | Sirisha Donekal | - |
dc.contributor.googleauthor | Anders Opdahl | - |
dc.contributor.googleauthor | Andre L.C. Almeida | - |
dc.contributor.googleauthor | Colin O. Wu | - |
dc.contributor.googleauthor | Antoinette S. Gomes | - |
dc.contributor.googleauthor | David A. Bluemke | - |
dc.contributor.googleauthor | Joao A.C. Lima | - |
dc.identifier.doi | 10.1093/eurheartj/eht133 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04165 | - |
dc.relation.journalcode | J00805 | - |
dc.identifier.eissn | 1522-9645 | - |
dc.identifier.pmid | 23644181 | - |
dc.identifier.url | http://eurheartj.oxfordjournals.org/content/34/30/2354.long | - |
dc.subject.keyword | Cardiovascular events | - |
dc.subject.keyword | Heart failure | - |
dc.subject.keyword | Myocardial function | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 34 | - |
dc.citation.number | 30 | - |
dc.citation.startPage | 2354 | - |
dc.citation.endPage | 2361 | - |
dc.identifier.bibliographicCitation | EUROPEAN HEART JOURNAL, Vol.34(30) : 2354-2361, 2013 | - |
dc.identifier.rimsid | 34244 | - |
dc.type.rims | ART | - |
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