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Cited 27 times in

Risk Factors for Neurologic Complications of Hand, Foot and Mouth Disease in the Republic of Korea, 2009

DC FieldValueLanguage
dc.contributor.author김기환-
dc.contributor.author김동수-
dc.contributor.author김지홍-
dc.date.accessioned2014-12-18T09:01:15Z-
dc.date.available2014-12-18T09:01:15Z-
dc.date.issued2013-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87382-
dc.description.abstractIn 2009, the first outbreak of hand, foot and mouth disease (HFMD) or herpangina (HP) caused by enterovirus 71 occurred in the Republic of Korea. This study inquired into risk factors associated with complications of HFMD or HP. A retrospective medical records review was conducted on HFMD or HP patients for whom etiologic viruses had been verified in 2009. One hundred sixty-eight patients were examined for this investigation. Eighty patients were without complications while 88 were accompanied by complications, and 2 had expired. Enterovirus 71 subgenotype C4a was the most prevalent in number with 67 cases (54.9%). In the univariate analysis, the disease patterns of HFMD rather than HP, fever longer than 4 days, peak body temperature over 39℃, vomiting, headache, neurologic signs, serum glucose over 100 mg/dL, and having an enterovirus 71 as a causative virus were significant risk factors of the complications. After multiple logistic analysis, headache (Odds ratio [OR], 10.75; P < 0.001) and neurologic signs (OR, 42.76; P < 0.001) were found to be the most significant factors. Early detection and proper management of patients with aforementioned risk factors would be necessary in order to attain a better clinical outcome.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHBlood Glucose/analysis-
dc.subject.MESHBody Temperature-
dc.subject.MESHEnterovirus A, Human/genetics-
dc.subject.MESHEnterovirus A, Human/isolation & purification-
dc.subject.MESHFemale-
dc.subject.MESHFever/etiology-
dc.subject.MESHGenotype-
dc.subject.MESHHand, Foot and Mouth Disease/complications*-
dc.subject.MESHHand, Foot and Mouth Disease/virology-
dc.subject.MESHHeadache/etiology-
dc.subject.MESHHerpangina/complications*-
dc.subject.MESHHerpangina/virology-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOdds Ratio-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHVomiting/etiology-
dc.subject.MESHYoung Adult-
dc.titleRisk Factors for Neurologic Complications of Hand, Foot and Mouth Disease in the Republic of Korea, 2009-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorSeong Joon Kim-
dc.contributor.googleauthorJong-Hyun Kim-
dc.contributor.googleauthorJin-Han Kang-
dc.contributor.googleauthorDong Soo Kim-
dc.contributor.googleauthorKi Hwan Kim-
dc.contributor.googleauthorKyung-Hyo Kim-
dc.contributor.googleauthorYoung-Hoon Kim-
dc.contributor.googleauthorJu-Young Chung-
dc.contributor.googleauthorJoong Hyun Bin-
dc.contributor.googleauthorDa Eun Jung-
dc.contributor.googleauthorJi Hong Kim-
dc.contributor.googleauthorHwang Min Kim-
dc.contributor.googleauthorDoo-Sung Cheon-
dc.contributor.googleauthorByung Hak Kang-
dc.contributor.googleauthorSoon Young Seo-
dc.identifier.doi10.3346/jkms.2013.28.1.120-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01003-
dc.contributor.localIdA00344-
dc.contributor.localIdA00405-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid23341722-
dc.subject.keywordCoxsackievirus-
dc.subject.keywordEnterovirus A, Human-
dc.subject.keywordHand, Foot and Mouth Disease-
dc.subject.keywordHerpangina-
dc.subject.keywordRisk Factors-
dc.contributor.alternativeNameKim, Ki Hwan-
dc.contributor.alternativeNameKim, Dong Soo-
dc.contributor.alternativeNameKim, Ji Hong-
dc.contributor.affiliatedAuthorKim, Ji Hong-
dc.contributor.affiliatedAuthorKim, Ki Hwan-
dc.contributor.affiliatedAuthorKim, Dong Soo-
dc.rights.accessRightsfree-
dc.citation.volume28-
dc.citation.number1-
dc.citation.startPage120-
dc.citation.endPage127-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.28(1) : 120-127, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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