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Application of the Adjuvant! Online Model to Korean Breast Cancer Patients: An Assessment of Prognostic Accuracy and Development of an Alternative Prognostic Tool

DC FieldValueLanguage
dc.contributor.author남정모-
dc.contributor.author노재경-
dc.contributor.author라선영-
dc.contributor.author양우익-
dc.contributor.author이수현-
dc.contributor.author정민규-
dc.contributor.author정현철-
dc.contributor.author정희철-
dc.date.accessioned2014-12-18T08:57:57Z-
dc.date.available2014-12-18T08:57:57Z-
dc.date.issued2013-
dc.identifier.issn1068-9265-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87282-
dc.description.abstractBACKGROUND: Adjuvant! Online (AOL) is a Web-accessible risk-assessment model that predicts the mortality and the benefits of adjuvant therapy for breast cancer. METHODS: Using the Yonsei Tumor Registry database, patients with T1-3, N0-3, M0 breast cancer who were treated at the Yonsei Cancer Center between 1986 and 1999 were entered into AOL version 8.0 to calculate survival. RESULTS: The median age of the study population was 45 years (range, 23-76 years) and the median follow-up duration was 10.8 years (range, 0.1-25.9 years) for all 699 patients. AOL significantly overestimated overall survival (OS) (by 11.1 %, P < 0.001), breast cancer-specific survival (BCSS) (by 11.6 %, P < 0.001), and event free-free survival (EFS) (by 9.25 %, P < 0.001) in Korean patients. Therefore, we developed a Korean version of AOL (KAOL), which is a new model for prognosis based on AOL's parameters. The observed 10-year OS (61.4 %), BCSS (62.3 %), and EFS (59.1 %) and the KAOL predicted OS (61.5 %), BCSS (63.5 %) and EFS (57.6 %) were not different (P = 0.976, P = 0.771, and P = 0.674, respectively). CONCLUSIONS: AOL was not found to be suitable in Korean patients with breast cancer. The newly developed KAOL accurately predicted 10-year outcomes in Korean breast cancer patients.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfAnnals of Surgical Oncology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleApplication of the Adjuvant! Online Model to Korean Breast Cancer Patients: An Assessment of Prognostic Accuracy and Development of an Alternative Prognostic Tool-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorMinkyu Jung-
dc.contributor.googleauthorEun Hee Choi-
dc.contributor.googleauthorChung Mo Nam-
dc.contributor.googleauthorSun Young Rha-
dc.contributor.googleauthorHei Cheul Jeung-
dc.contributor.googleauthorSoo Hyun Lee-
dc.contributor.googleauthorWoo Ick Yang-
dc.contributor.googleauthorJae Kyung Roh-
dc.contributor.googleauthorHyun Cheol Chung-
dc.identifier.doi10.1245/s10434-013-2956-z-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01264-
dc.contributor.localIdA01290-
dc.contributor.localIdA02300-
dc.contributor.localIdA03606-
dc.contributor.localIdA03773-
dc.contributor.localIdA03794-
dc.contributor.localIdA01316-
dc.contributor.localIdA02898-
dc.relation.journalcodeJ00179-
dc.identifier.urlhttp://link.springer.com/article/10.1245%2Fs10434-013-2956-z-
dc.contributor.alternativeNameNam, Jung Mo-
dc.contributor.alternativeNameRoh, Jae Kyung-
dc.contributor.alternativeNameRha, Sun Young-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.alternativeNameLee, Soo Hyeon-
dc.contributor.alternativeNameJung, Min Kyu-
dc.contributor.alternativeNameChung, Hyun Cheol-
dc.contributor.alternativeNameJeung, Hei Cheul-
dc.contributor.affiliatedAuthorNam, Jung Mo-
dc.contributor.affiliatedAuthorRoh, Jae Kyung-
dc.contributor.affiliatedAuthorYang, Woo Ick-
dc.contributor.affiliatedAuthorJung, Min Kyu-
dc.contributor.affiliatedAuthorChung, Hyun Cheol-
dc.contributor.affiliatedAuthorJeung, Hei Cheul-
dc.contributor.affiliatedAuthorRha, Sun Young-
dc.contributor.affiliatedAuthorLee, Soo Hyeon-
dc.rights.accessRightsnot free-
dc.citation.volume20-
dc.citation.number8-
dc.citation.startPage2615-
dc.citation.endPage2624-
dc.identifier.bibliographicCitationAnnals of Surgical Oncology, Vol.20(8) : 2615-2624, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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