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Economic Evaluation of the National Immunization Program of Rotavirus Vaccination for Children in Korea

Authors
 Hye-Young Kang  ;  Ki Hwan Kim  ;  Ji Hong Kim  ;  Hwang Min Kim  ;  Jinkyung Kim  ;  Mi-Sun Kim  ;  Antoine C. El Khoury  ;  Dong Soo Kim 
Citation
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH, Vol.25(2) : 145-158, 2013 
Journal Title
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH 
ISSN
 1010-5395 
Issue Date
2013
MeSH
Child, Preschool ; Cost of Illness ; Cost-Benefit Analysis ; Follow-Up Studies ; Humans ; Immunization Programs/economics* ; Infant ; Markov Chains ; Program Evaluation/economics ; Republic of Korea ; Rotavirus Infections/economics ; Rotavirus Infections/prevention & control* ; Rotavirus Vaccines/economics* ; Vaccines, Attenuated/economics
Keywords
cost-effectiveness ; rotavirus ; vaccination
Abstract
The authors assessed the cost-effectiveness of rotavirus vaccination to develop an evidence-based national immunization program in Korea. A Markov model was constructed to compare the costs and clinical outcomes of vaccination versus no vaccination. The birth cohort of 493189 infants in 2007 was followed until the age of 5 years. Korea-specific data for epidemiological characteristics and economic burden of rotavirus diarrhea were used for the modeled estimation. Efficacy of RotaTeq® was based on a recent clinical trial. Rotavirus vaccination would prevent 181238 symptomatic cases (reduction rate = 63.2%) over 5 years after birth. From the societal perspective, at a vaccination cost of 100000 Korean won (KW; 1 US$ ≈ 1200 KW) per dose, universal vaccination would cost 375 620 KW per case averted. The breakeven price of vaccine was 56061 KW. Rotavirus vaccination would reduce the burden of the disease substantially and be a cost-effective strategy to prevent rotavirus diarrhea in Korea.
Full Text
http://aph.sagepub.com/content/25/2/145.long
DOI
10.1177/1010539511416806
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ki Hwan(김기환)
Kim, Dong Soo(김동수)
Kim, Ji Hong(김지홍) ORCID logo https://orcid.org/0000-0001-5352-5423
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/87234
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